Surgical management of a rare case of giant penile cancer.
We present a case of a patient with a giant primary penile cancer managed with radical penectomy, bilateral inguinal lymphadenectomy and perineal urethrostomy, who experienced disease recurrence 6 months after surgery and died with metastatic disease after denial of further treatment. The management of our case was challenging due to the extremely late diagnosis, the huge dimensions and the infiltrative nature of the tumour; however, from a histopathological perspective, the cancer itself did not display any microscopic peculiarity. Our case highlights that such bulky penile tumors can still occur in current urologic pract...
Source: Minerva Urologica e Nefrologica - November 15, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Phase I study of a new tablet based image guided surgical system in robotic assisted radical prostatectomy.
Authors: Kratiras Z, Gavazzi A, Belba A, Willis B, Chew S, Allen C, Amoroso P, Dasgupta P
Abstract
Robotic assisted radical prostatectomy is, currently, the most commonly utilized procedure for the treatment of localized prostate cancer. Image-guided surgical systems have been proposed in the literature as a valuable tool for the better utilization of the preoperative data in theatre. In this Phase 1 trial, we tested the feasibility and safety of a new, cutting - edge tablet based surgical imaging system designed for Robotic assisted radical prostatectomy (RARP). It utilizes the preoperative MRI images of ...
Source: Minerva Urologica e Nefrologica - November 15, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
R.U.G. technique: replacement of the ureter with gonadal vein. A cadaveric study.
CONCLUSIONS: The RUG technique resulted in an adequate, safe and easy-to-perform surgical alternative.
PMID: 30421594 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - November 15, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Cold ischemia technique during robotic partial nephrectomy: a propensity score-matched comparison with open approach.
CONCLUSIONS: In our experience, cold ischemia technique can be effectively reproduced during RPN, with a potential advantage in terms of blood loss, complications rate and hospital stay over the traditional OPN procedure.
PMID: 30421595 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - November 15, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Intraoperative assessment of ureteral and graft reperfusion during robotic kidney transplantation with indocyanine green fluorescence videography: a pilot study and systematic review of the literature.
CONCLUSIONS: IFV during RAKT is feasible and safe and provides a reliable assessment of graft reperfusion. Larger studies are needed to standardize the technique and to evaluate the association between fluorescence signal, ultrasound parameters and postoperative kidney function.
PMID: 30421596 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - November 15, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
The role of side-specific biopsy and dominant tumor location at radical prostatectomy in predicting the side of nodal metastases in organ confined prostate cancer: is lymphatic spread really unpredictable?
CONCLUSIONS: Our results suggest confirmed that a unilateral LN dissection limited to the tumor-bearing side of the gland evaluated by biopsy specimens should not be recommended due to the substantial risk of missing contralateral LNMs.
PMID: 30421597 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - November 15, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
BCG unresponsive in patients with NMIBC: what the urologists must know. A review of the current literature.
Authors: Moschini M, Zamboni S, Mattei A, Amparore D, Fiori C, De Dominicis C, Esperto F
Abstract
Transurethral resection of bladder (TURB) with adjuvant intravesical bacillus Calmette-Guerin (BCG) remains the gold standard therapy for intermediate and high risk non-muscle invasive bladder cancer (NMIBC). However, this disease is burdened with a high risk of recurrence or progression. For this reason, we sought to review and summarize the current evidence with a non-systematic Medline/Pubmed literature search, regarding optimal treatment in BCG-failure patients. Radical cystectomy (RC) should be considered...
Source: Minerva Urologica e Nefrologica - November 15, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Prostate specific antigen levels and proportion of biopsy positive cores are independent predictors of upgrading patterns in low risk prostate cancer.
CONCLUSIONS: PSA and BPC were both independent predictors of tumour upgrading in low risk PCA. BPC associated with the risk of intermediate tumour upgrading patterns, but showed a low discrimination power. PSA associated with high upgrading patterns and showed a fair discrimination power in the model. Tumour upgrading risk patterns should be evaluated in low risk PCA patients before treatment.
PMID: 30298710 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - October 10, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Intraprostatic Injections for LUTS/BPH treatment.
CONCLUSIONS: Intraprostatic injections are still to be considered investigational for the minimally invasive management of LUTS/BPE patients. Emerging data suggest a possible role of new agents in the near future when definitive data of ongoing RCTs will be available.
PMID: 30298711 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - October 10, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Biological bases of radical prostatectomy in the management of prostate cancer patients with oligometastatic disease.
Authors: Dalla Volta A, Antonelli A, Simeone C, Berruti A
PMID: 30298712 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - October 10, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Ischemia time and beyond: the concept of global renal damage.
Authors: Mir MC, Autorino R, Porpiglia F
PMID: 30256078 [PubMed - in process] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - September 27, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Improved prediction of nephron-sparing surgery versus radical nephrectomy by the optimized R.E.N.A.L. (optR.E.N.A.L.) score in patients undergoing surgery for renal masses.
CONCLUSIONS: optR.E.N.A.L. represents a promising improvement of the preexisting R.E.N.A.L. score with higher predictive ability for nephrectomy type than established MS and may serve as a benchmarking tool for nephrectomy assessment and comparison of surgical strategies.
PMID: 30256079 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - September 27, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Long-term oncologic and functional outcomes after robot-assisted partial nephrectomy in elderly patients.
CONCLUSIONS: In a high-volume center, robot-assisted approach is feasible and safe in surgical fit elderly patients with good long-term oncologic outcomes.
PMID: 30230293 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - September 20, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Adherence to hormonal deprivation therapy in prostate cancer in clinical practice: a retrospective, single-centre study.
CONCLUSIONS: Adherence to ADT was optimal, probably owing to its balanced side effect and benefit profile. Patient's death was the most frequent reason for discontinuation.
PMID: 30230294 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - September 20, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
Cigarette smoking is not associated with prostate cancer diagnosis and agressiveness: a cross sectional italian study.
CONCLUSIONS: In our cross-sectional study, smoking is not predictive of PCa or high-grade disease. Further studies should evaluate if smoking could influence PCa diagnosis and aggressiveness.
PMID: 30230295 [PubMed - as supplied by publisher] (Source: Minerva Urologica e Nefrologica)
Source: Minerva Urologica e Nefrologica - September 20, 2018 Category: Urology & Nephrology Tags: Minerva Urol Nefrol Source Type: research
