A Milestone for the Journal of Thoracic Oncology
No abstract available (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - November 24, 2015 Category: Cancer & Oncology Tags: Editorials Source Type: research
In This Issue/Research Watch/News In Brief/News from the IASLC Tobacco Control Committee
No abstract available (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - November 24, 2015 Category: Cancer & Oncology Tags: In This Issue/Research Watch/News In Brief/News from the IASLC Tobacco Control Committee Source Type: research
Pruritus as a Paraneoplastic Symptom of Thymoma
No abstract available (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 24, 2015 Category: Cancer & Oncology Tags: Case Report Source Type: research
Patient-Reported Outcomes and Quality of Life in PROFILE 1007: A Randomized Trial of Crizotinib Compared with Chemotherapy in Previously Treated Patients with ALK-Positive Advanced Non–Small-Cell Lung Cancer: Erratum
No abstract available (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 24, 2015 Category: Cancer & Oncology Tags: Erratum Source Type: research
An Uncommon Presentation of Brain Metastases in a Lung Cancer Patient
No abstract available (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 24, 2015 Category: Cancer & Oncology Tags: Image of the Month Source Type: research
Spontaneous Pulmonary Torsion Secondary to Left Upper Lobe Malignancy
No abstract available (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 24, 2015 Category: Cancer & Oncology Tags: Image of the Month Source Type: research
Clinical Implications of Variant ALK FISH Rearrangement Patterns
Conclusions: Patients with 5′ deletion on ALK FISH harbor features less typical of ALK-rearranged tumors, potentially indicating that some cases with this variant are false positives. Corroborative testing with IHC or NGS may be beneficial. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 24, 2015 Category: Cancer & Oncology Tags: Brief Report Source Type: research
Impact of Positive Nodal Metastases in Patients with Thymic Carcinoma and Thymic Neuroendocrine Tumors
Conclusions: Nodal status seems to be an important prognostic factor in patients with thymic carcinoma and thymic neuroendocrine tumors. Nodal sampling should be performed during resection of these thymic malignancies. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 24, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
A New Prognostic Score Supporting Treatment Allocation for Multimodality Therapy for Malignant Pleural Mesothelioma: A Review of 12 Years’ Experience
Conclusion: Patients receiving induction chemotherapy followed by EPP for MPM of all histological subtypes and irrespective of nodal status showed a median survival of 22 months. A prognostic score is proposed to help patient allocation for surgery after validation in an independent cohort. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 24, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Survival After Sublobar Resection versus Lobectomy for Clinical Stage IA Lung Cancer: An Analysis from the National Cancer Data Base
Conclusion: In this large national-level, clinically diverse sample of clinical T1A NSCLC patients, wedge and segmental resections were shown to have significantly worse OS compared with lobectomy. Further patients undergoing sublobar resection were more likely to have inadequate lymphadenectomy and positive margins. Ongoing prospective study taking into account LN upstaging and margin status is still needed. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 24, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Treatment and Prognosis of Isolated Local Relapse after Stereotactic Body Radiotherapy for Clinical Stage I Non–Small-Cell Lung Cancer: Importance of Salvage Surgery
Conclusions: It was confirmed that our patient selection for salvage surgery for isolated LR was associated with favorable survival outcomes. Operability based on multidisciplinary conferences, rather than measurable patient characteristics, is essential for appropriate patient selection for salvage surgery. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 24, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Impact of a Contralateral Tumor Nodule on Survival in Non–Small-Cell Lung Cancer
Conclusions: Contralateral tumors in NSCLC carry a more favorable prognosis than other M1a or M1b disease. Primary tumor size and N stage may help distinguish M1a-contra patients with hematogenous metastasis from those with a synchronous, second primary. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 24, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Pattern of Failure Analysis in Metastatic EGFR-Mutant Lung Cancer Treated with Tyrosine Kinase Inhibitors to Identify Candidates for Consolidation Stereotactic Body Radiation Therapy
Conclusion: Initial progression of TKI-treated cancers occurred predominantly in original disease sites. Consolidation SBRT was judged feasible in a subset of patients following maximum TKI response and may have prevented oligoprogression in most of these. In addition, we hypothesize that consolidation SBRT for residual disease could delay subsequent metastatic reseeding. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 24, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Clinicopathological and Survival Analysis of Japanese Patients with Resected Non–Small-Cell Lung Cancer Harboring NKX2-1, SETDB1, MET, HER2, SOX2, FGFR1, or PIK3CA Gene Amplification
Conclusions: The amplification status differed among the histological types of NSCLC. NKX2-1 amplification was an independent and the most practically important predictor of a poor prognosis among Japanese patients with AC. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 24, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Refining Prognosis in Lung Cancer: A Report on the Quality and Relevance of Clinical Prognostic Tools
Conclusions: Prognostic tools will contribute more meaningfully to the practice of personalized medicine if better study design and analysis approaches are used in their development and validation. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - October 24, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
