Clinical Implications of Variant ALK FISH Rearrangement Patterns

Conclusions: Patients with 5′ deletion on ALK FISH harbor features less typical of ALK-rearranged tumors, potentially indicating that some cases with this variant are false positives. Corroborative testing with IHC or NGS may be beneficial.
Source: Journal of Thoracic Oncology - Category: Cancer & Oncology Tags: Brief Report Source Type: research