Central Nervous System Pseudoprogression in a Patient Treated with PD-1 Checkpoint Inhibitor
No abstract available (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Case Reports Source Type: research
Durable Response to Tyrosine Kinase Inhibitor Therapy in a Lung Cancer Patient Harboring Epidermal Growth Factor Receptor Tandem Kinase Domain Duplication
No abstract available (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Case Reports Source Type: research
A Rare Subglottic Capillary Hemangioma
No abstract available (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Image of the Month Source Type: research
Challenging Lung Carcinoma with Coexistent ΔNp63/p40 and Thyroid Transcription Factor-1 Labeling Within the Same Individual Tumor Cells
No abstract available (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Image of the Month Source Type: research
Cystic Mediastinal Thymic Lymphangioma Mimicking Echinococcal Cyst
No abstract available (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Image of the Month Source Type: research
Conditional Survival of Esophageal Cancer: An Analysis from the SEER Registry (1988–2011)
Conclusions: Conditional survival showed improving prognosis over time. Patients with advanced stage had the most dramatic improvement. Clinicians, caregivers, and patients with esophageal cancer can feel encouraged by the improving prognosis with each year survived. This information has practical implications regarding longitudinal follow-up guidelines and survivorship planning. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Postchemoradiotherapy Pathologic Stage Classified by the American Joint Committee on the Cancer Staging System Predicts Prognosis of Patients with Locally Advanced Esophageal Squamous Cell Carcinoma
Conclusions: The post-CRT pathologic stage classified by American Joint Committee on Cancer, 7th edition staging system predicted the survival of locally advanced ESCC patients who underwent preoperative paclitaxel and cisplatin-based CRT followed by esophagectomy. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Survival Benefit of Surgery after Chemoradiotherapy for Stage III (N0–2) Non–Small-Cell Lung Cancer Is Dependent on Pathologic Nodal Response
Conclusions: Surgical patients with complete nodal clearance experienced superior survival, but those with RND fared no better than CRT alone. Mediastinal response may play an important role in the decision to proceed with surgical resection after CRT for stage III NSCLC. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Evaluating Cryoablation of Metastatic Lung Tumors in Patients—Safety and Efficacy: The ECLIPSE Trial—Interim Analysis at 1 Year
Conclusion: Cryoablation is a safe and effective treatment for pulmonary metastases with preserved quality of life following intervention. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Safety and Immunogenicity of MAGE-A3 Cancer Immunotherapeutic with or without Adjuvant Chemotherapy in Patients with Resected Stage IB to III MAGE-A3-Positive Non–Small-Cell Lung Cancer
Conclusion: In resected and unresectable NSCLC patients and irrespective of whether standard chemotherapy was concurrent or not, MAGE-A3 immunotherapeutic is well tolerated and induces MAGE-A3-specific immune responses. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Targeted Therapy for Patients with BRAF-Mutant Lung Cancer: Results from the European EURAF Cohort
Conclusions: These results confirm the activity of targeted therapy in patients with BRAF-mutant lung adenocarcinoma. Further trials are warranted to study combination therapies and drug resistance mechanisms. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Negative Thyroid Transcription Factor 1 Expression Defines an Unfavorable Subgroup of Lung Adenocarcinomas
Conclusions: TTF1– correlated with solid and invasive mucinous subtypes of lung adenocarcinoma and lower frequency of EGFR mutations. It defines a subgroup of lung adenocarcinomas with unfavorable outcomes. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Early Prediction of Response to Tyrosine Kinase Inhibitors by Quantification of EGFR Mutations in Plasma of NSCLC Patients
Conclusions: Quantification of EGFR mutations from plasma with a standardized PCR test is feasible. To our knowledge, this is the first study showing a strong correlation between the EGFR SQI in the first days of treatment and clinical response with relevant implications for patient management. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Somatic Mutation Spectrum of Non–Small-Cell Lung Cancer in African Americans: A Pooled Analysis
Conclusions: We demonstrated that NSCLC from AAs has a different pattern of somatic driver mutations than from Caucasians. The majority of driver alterations in this group are yet to be described, which will require more comprehensive panels and assessment of noncanonical alterations. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
Impact of an Interactive On-line Tool on Therapeutic Decision-Making for Patients with Advanced Non–Small-Cell Lung Cancer
Conclusion: This online tool for treatment decision-making resulted in a positive influence on clinician’s decisions. This approach offers opportunities for improving quality of care and meets an educational need in application of new therapeutic paradigms. (Source: Journal of Thoracic Oncology)
Source: Journal of Thoracic Oncology - September 26, 2015 Category: Cancer & Oncology Tags: Original Articles Source Type: research
