Journal of the Egyptian National Cancer Institute 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Role of thyroid transcription factor-1 and P63 immunocytochemistry in cytologic typing of non-small cell lung carcinomas
Conclusion TTF-1 achieved moderate sensitivity, and high specificity in the diagnosis of AC, while P63 was highly sensitive and specific for the diagnosis of SCC. Immunocytochemistry raised the sensitivity and specificity of FNAC in diagnosing AC and SCC using TTF-1 and P63, respectively. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
Breast cancer laterality among Egyptian patients and its association with treatments and survival
Conclusions Among Egyptian patients, the left breast is at greater risk of cancer than the right one. Despite right-sided tumors seemed more aggressive, Left-sided ones tend to confer worse survival than right-sided tumors. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
Role of cyclins A and E in endometrial carcinogenesis in breast cancer patients under tamoxifen treatment
Conclusion Cyclins A and E expression is involved in the carcinogenesis of endometrium in women with breast cancer and under tamoxifen-treatment. Follow up of the patients using these 2 markers is highly recommended starting from the 12th month. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
Role of Ki67 in predicting resistance to adjuvant tamoxifen in postmenopausal breast cancer patients
Conclusion High Ki67 expression is predictive of poor prognosis and of resistance to adjuvant tamoxifen therapy in postmenopausal BC. We recommend considering Ki67 as one of the risk factors that guide adjuvant treatment decisions. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
Role of glypican-3 immunocytochemistry in differentiating hepatocellular carcinoma from metastatic carcinoma of the liver utilizing fine needle aspiration cytology
Publication date: December 2013 Source:Journal of the Egyptian National Cancer Institute, Volume 25, Issue 4 Author(s): Mohamed Zaakook , Menar Ayoub , Eman Abu Sinna , Samar El-Sheikh (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
Systemic therapy for hepatocellular carcinoma (HCC): from bench to bedside
Publication date: December 2013 Source:Journal of the Egyptian National Cancer Institute, Volume 25, Issue 4 Author(s): Omar Abdel-Rahman Primary liver cancer is the fifth most common cancer worldwide and the third most common cause of cancer mortality. For patients with early resectable disease, surgical resection or transplantation is considered a potentially curative modality for hepatocellular carcinoma (HCC); on the other hand, for patients with unresectable or metastatic disease, treatment is essentially palliative and prior to the approval of sorafenib, there was no globally approved systemic treatment for pati...
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
Primary mucinous adenocarcinoma of the renal pelvis with carcinoma in situ in the ureter
Publication date: March 2014 Source:Journal of the Egyptian National Cancer Institute, Volume 26, Issue 1 Author(s): Mahmoud Abbas , Mario W. Kramer , Tilmann Spieker , Thomas R.W. Herrman , Axel S. Merseburger , Klaus-Michael Müller , Marcus A. Kuczyk , Jan U. Becker , Hans-Heinrich Kreipe Primary epithelial tumor of the renal pelvis is rare and only 100 cases are reported in the literature [1]. Histological examination of the tumor showed glands, cysts, and papillae lined by pseudostratified columnar epithelium with hyperchromatic nuclei. Scattered signet ring-type cells were also seen floating in large poo...
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
Prognostic value of IDH1 mutations identified with PCR-RFLP assay in acute myeloid leukemia patients
Conclusion IDH1 mutations are recurring genetic alterations in AML and they may have unfavorable impact on clinical outcome in adult AML. The PCR-RFLP method allows for a fast, inexpensive, and sensitive method for the detection of IDH1 mutations in AML. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
ERα and ERK1/2 MAP kinase expression in microdissected stromal and epithelial endometrial cells
Publication date: March 2014 Source:Journal of the Egyptian National Cancer Institute, Volume 26, Issue 1 Author(s): Said Abu Alkhair Mohamed , Ihab Shafek Atta , Brian G. Rowan , Mohamed Mokhtar Desouki Our previous published data detected higher expression of total and active mitogen activated protein kinase (MAPK) in the epithelial vs. stromal cells of the endometrium. In the present work we compared the expression of ERK1/2 MAPK and estrogen receptor α (ERα) in epithelial versus stromal cells in benign human endometrial tissues. Laser capture microdissection was used to separate glandular epithelium and strom...
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
Prognostic value of lymph node ratio in node-positive breast cancer in Egyptian patients
Conclusion The analysis of outcome of patients with early breast cancer in Egypt identified the adverse prognostic effects of high tumor grade, ER negativity and intermediate and high LNR on DFS. If the utility of the LNR is validated in other studies, it may replace the use of absolute number of axillary lymph nodes. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
Age at diagnosis in women with non-metastatic breast cancer: Is it related to prognosis?
Conclusion Young women were not found to have poorer prognosis, yet they presented with more ER negative tumors. Most of women presented with advanced stage and young women had higher recurrence rates. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
Basal cell hyperplasia (BCH) versus high grade prostatic intraepithelial neoplasia (HGPIN) in tiny prostatic needle biopsies: Unusual diagnostic dilemma
Publication date: March 2014 Source:Journal of the Egyptian National Cancer Institute, Volume 26, Issue 1 Author(s): Fatma El-Zahraa Salah El-Deen Yassin , Eman M.S. Muhammad , Mohammed Zaki , Mohammed Dyaa Saleem , Rabab Ahmed Ahmed Mohammed Background Histopathological differentiation between BCH and HGPIN in prostatic needle biopsies is a diagnostic challenge. The gold standard for detection of HGPIN and BCH is histopathological examination; however subjectivity in interpretation and tiny volume of obtained tissue hamper reliable diagnosis. Aims The aim of this study was to assess usefulness of using the p63 ...
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
Sorafenib for Egyptian patients with advanced hepatocellular carcinoma; single center experience
Conclusions In limited resource countries like Egypt, we suggest that the use of sorafenib for the treatment of advanced HCC cases should be restricted to a highly selected subgroup of patients with good performance and child A. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
Tamoxifen compared to best supportive care in advanced hepatocelluar carcinoma: A retrospective matched-cohort study
Conclusions Tamoxifen did not show any OS advantage in Egyptian patients with advanced HCC. Use of this drug is discouraged. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
Treatment outcomes of female germ cell tumors: The Egyptian National Cancer Institute experience
Conclusions Female GCTs rarely affect Egyptian females. They have good prognosis. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research
