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Isolated skeletal muscle metastatic deposit in a patient with micropapillary carcinoma thyroid identified by 18F FDG PET CT
We report the identification of an isolated FDG avid muscle deposit in a treated case of micropapillary carcinoma of the right lobe and widely invasive follicular carcinoma of the left lobe thyroid gland. Patient was found to have an elevated thyroglobulin level with negative iodine scan (TENIS syndrome) on follow up at 6months. An 18F FDG PET CT (18 fluorine-fluorodeoxyglucose positron emission computed tomography) whole body study revealed a solitary FDG avid deltoid muscle deposit which was histopathologically confirmed to be metastatic papillary carcinoma. While follicular carcinoma is known to have distant metastases,...
Source: Journal of the Egyptian National Cancer Institute - February 17, 2015 Category: Cancer & Oncology Source Type: research

Dosimetric prospective study comparing 2D and 3D planning for irradiation of supraclavicular and infraclavicular regions in breast cancer patients
Conclusions From the present study we concluded that the coverage of the supraclavicular and infraclavicular PTV is significantly worse with the 2D technique using a single oblique field at a fixed depth of 3cm for all patients despite their different builts. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - January 25, 2015 Category: Cancer & Oncology Source Type: research

Sphincter saving and abdomino-perineal resections following neoadjuvant chemoradiation in locally advanced low rectal cancer
Conclusion In low rectal cancer, the sphincter preservation appears to have nearly the same oncologic outcome compared to APR, this might be attributed to the small sample size and short follow up period. However, patients with sphincter preservation have certainly demonstrated an indisputable better functional outcome, in terms of stoma avoidance and adequate continence. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - December 8, 2014 Category: Cancer & Oncology Source Type: research

Expression of a disintegrin and metalloprotease 8 and endostatin in human osteosarcoma: Implication in tumor progression and prognosis
Conclusion Our data suggest that ADAM8 and endostatin play a role in osteosarcoma progression. High ADAM8 expression serves as a reliable marker for poor prognosis in osteosarcoma patients. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - December 4, 2014 Category: Cancer & Oncology Source Type: research

Outcome of different oncoplastic surgical (OPs) techniques for centrally located breast cancer (CLBC)
Conclusion Multiple oncoplastic breast surgery techniques can be used for the resection of CLBC with satisfying cosmetic outcomes. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 16, 2014 Category: Cancer & Oncology Source Type: research

Comparison of abdominoperineal resection and low anterior resection in lower and middle rectal cancer
Conclusion LAR can provide comparable local control, disease free and overall survival rates compared with APR in eligible patients with lower and middle rectal cancer. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Transarterial chemoembolization for the treatment of hepatocellular carcinoma: A single center experience including 221 patients
Conclusion TACE produces reasonable responses and fair survival rates in locally advanced HCC but with noticeable toxicities. Proper patients’ selection and prompt liver support are mandates for improving TACE outcomes. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

The prognostic significance of minimal residual disease in adult Egyptian patients with precursor acute lymphoblastic leukemia
Conclusion MRD by FCM is a strong independent predictor of outcome in terms of DFS and OS and is a powerful informative parameter in guiding individual treatment in ALL patients. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Angiomyolipoma of the kidney: Clinicopathological and immunohistochemical study
Conclusion AMLs have characteristic clinicopathological and immunohistochemical features and their recognition is crucial for proper diagnosis and treatment. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Groin recurrence in patients with early vulvar cancer following superficial inguinal node dissection
Conclusion Carcinoma of the vulva with the following criteria (size of tumor is greater than 3cm, depth of invasion greater than 5mm, and high grade tumors) is at high risk of recurrence. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

CCAAT/enhancer binding protein α gene expression in Egyptian patients with acute myeloid leukemia
Conclusion We conclude that the majority of the AML patients analyzed, express low levels of C/EBPa mRNA. However, a subset of patients represented by the M3 subtype, express higher levels of C/EBPa. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Small intestinal cancers among adults in an Egyptian district: A clinicopathological study using a population-based cancer registry
Conclusions SICs in Gharbiah, Egypt are characterized by predominance of female gender and adenocarcinoma histology. One year survival is 64% with a poor outcome for adenocarcinoma and duodenal subsite. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Gastric diffuse large B cell lymphoma presenting as paraneoplastic cerebellar degeneration: Case report and review of literature
We report a case of PCD associated with gastric diffuse large B-cell lymphoma (DLBCL) in a patient who presented with acute onset of giddiness and double vision and had complete remission of the gastric lesion and marked improvement of cerebellar syndrome with rituximab-based combination chemotherapy. A brief review of the literature is also presented. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

DJ-1 and androgen receptor immunohistochemical expression in prostatic carcinoma: A possible role in carcinogenesis
Conclusion AR nuclear expression was consistently present in benign and adenocarcinoma epithelium. But, there may be limited clinical use for AR expression in localized carcinoma due to its constant heterogeneity. DJ-1 with its oncogenic properties, specificity for prostatic carcinoma and homogenous expression gives an ideal complementary role to AR in the detection and treatment of prostatic carcinomas. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Outcome of fertility preserving surgery in early stage ovarian cancer
Conclusion Fertility preserving surgery can be considered a safe treatment strategy in patients with stage IA, G1 or G2 ovarian carcinoma. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research