Scattered radiation to gonads: Role of testicular shielding for para-aortic and homolateral illiac nodal radiotherapy
Conclusions With proper testicular shielding, doses as low as 0.28% of the prescribed dose can be achieved. This low dose is believed to maintain the fertility of the patient. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

When would we advocate a total thyroidectomy in cases of hypopharyngeal carcinoma?
Conclusion We would advocate a total thyroidectomy in cases of advanced stages of hypopharyngeal carcinoma, bilateral tumors, postcricoid carcinoma and in all patients with definite radiological evidence of thyroid gland invasion. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Evaluation of the frequency and pattern of local recurrence following intersphincteric resection for ultra-low rectal cancer
Conclusion Intersphincteric resection with TME does not affect the local recurrence or overall survival rate in early rectal cancer T1-2 & 3, with preservation of bowel continuity and better life quality. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Comparing Prothrombin induced by vitamin K absence-II (PIVKA-II) with the oncofetal proteins Glypican-3, Alpha feto protein and Carcinoembryonic antigen in diagnosing hepatocellular carcinoma among Egyptian patients
Conclusion Glypican-3 is the only oncofetal antigen that showed comparable high diagnostic accuracy as PIVKA-II in diagnosing HCC among Egyptian patients. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Source, pattern and antibiotic resistance of blood stream infections in hematopoietic stem cell transplant recipients
Conclusion In one year duration, gram negative pathogens were the predominant causes of infection in HSCT recipients with high rates of MDROs in our institution. Gastroenteritis and central venous line infections are the main sources of bacteremia. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

A descriptive study of plasma cell dyscrasias in Egyptian population
Conclusion Long term follow up is required to further define the role of different therapeutic lines of treatment including ASCT in the various stages of PCD based on OS data. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Assessment of leptin and resistin levels in non-obese multiple myeloma patients and their relation with Ig level and disease stage
Conclusions Leptin may play a role in the pathogenesis of MM and its level may be changed in different stages. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

CDX2 gene expression in acute lymphoblastic leukemia
Publication date: June 2014 Source:Journal of the Egyptian National Cancer Institute, Volume 26, Issue 2 Author(s): Hanaa H. Arnaoaut , Doha A. Mokhtar , Rania M. Samy , Sahar A. Khames , Shereen A. Omar CDX genes are classically known as regulators of axial elongation during early embryogenesis. An unsuspected role for CDX genes has been revealed during hematopoietic development. The CDX gene family member CDX2 belongs to the most frequent aberrantly expressed proto-oncogenes in human acute leukemias and is highly leukemogenic in experimental models. We used reversed transcriptase polymerase chain reaction (RT-PC...
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Primitive neuroectodermal tumor masquerading meningioma
Publication date: Available online 29 August 2014 Source:Journal of the Egyptian National Cancer Institute Author(s): Vijay P. Joshi , Shirish Valsangkar , Anish Dekhne , Balaji Anvekar , Chakrapani Tumma , Amit Agrawal (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Rectal cancer in pregnancy: A diagnostic and therapeutic challenge
Conclusion This case suggests that colorectal cancer can mimic the signs and the symptoms of pregnancy and tends to present at an advanced stage in pregnant women. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Pelvic exenteration and composite sacral resection in the surgical treatment of locally recurrent rectal cancer
Conclusion Extended pelvic resection as pelvic exenteration and sacral resection for locally recurrent rectal cancer are effective procedures with tolerable mortality rate and acceptable outcome. The associated morbidity remains high and deserves vigilant follow up. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Isolated loco-regional recurrence after radical nephrectomy for renal cell carcinoma: A study of 22patients
Conclusion ILR after radical nephrectomy for RCC is more common with more advanced stages, where interval to recurrence tends to be shorter. The management should be surgical, which was possible in nearly 60% of cases. Complete excision was associated with better overall and disease free survival. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Skin sparing mastectomy: Technique and suggested methods of reconstruction
Conclusions Skin Sparing mastectomy through a circum-areolar incision has proven to be a safe and feasible option for the management of breast cancer in Egyptian women, offering them adequate oncologic control and optimum cosmetic outcome through preservation of the skin envelope of the breast when ever indicated. Our patients can benefit from safe surgery and have good cosmetic outcomeby applying different reconstructive techniques. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

The pattern of infection and antibiotics use in terminal cancer patients
Conclusions Our study revealed that antibiotic therapy for terminal cancer patients should be on a clear rationale. We need further study to clarify if there is survival effect with antibiotic use or not. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research

Weekly dose-dense paclitaxel and carboplatin in recurrent ovarian carcinoma: A phase II trial
Conclusion Weekly TC is active and well-tolerated in platinum-resistant and platinum-sensitive patients with recurrent EOC previously treated with TC given every 3weeks. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 12, 2014 Category: Cancer & Oncology Source Type: research