Journal of the Egyptian National Cancer Institute This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Small intestine and ovarian metastasis in a patient with a history of cardiac fibrosacoma
In this report, a 35year old woman a known case of cardiac fibrosarcoma was admitted to the emergency ward with abdominal pain and distention, bloody diarrhea, and recurrent nausea and vomiting. Jejuno-jejunal invagination was diagnosed at laparotomy along with tumoral involvement of the left ovary. Histopathological study showed that there was a fibrosarcoma compatible with the earlier diagnosis of primary cardiac tumor. We have described some aspects of diagnosis and treatment of this rare cause of intestinal intussusception. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - May 1, 2015 Category: Cancer & Oncology Source Type: research

Medullomyoblastoma treated with craniospinal radiation and adjuvant chemotherapy: Report of 4 cases and review of the literature
In this report, we describe the clinical features and treatment of 4 cases of MMB. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - April 29, 2015 Category: Cancer & Oncology Source Type: research

Bilateral clear cell sarcoma of the kidney
Publication date: Available online 28 April 2015 Source:Journal of the Egyptian National Cancer Institute Author(s): Wael Zekri , Dina Yehia , Maged M. Elshafie , Mohamed Saad Zaghloul , Naglaa El-Kinaai , Hala Taha , Amal Refaat , Alaa A. Younes , Ahmad Samir Alfaar Clear cell sarcoma of the kidney (CCSK) accounts for 2–5% of all pediatric renal malignancies, and is known for its propensity to metastasize to bone and other sites. We are reporting two cases with bilateral CCSK that were diagnosed at our institution. One patient initially presented with bilateral renal masses, as well as pulmonary, hepatic an...
Source: Journal of the Egyptian National Cancer Institute - April 29, 2015 Category: Cancer & Oncology Source Type: research

Non small cell carcinoma of lung with metachronous breast metastasis and cardiac tamponade: Unusual presentation of a common cancer
Conclusion The importance of this case is to highlight molecular profiling as an applicable tool to distinguish extra-mammary metastasis that masquerade as mammary neoplasm thereby preventing unnecessary need of surgery and radiation therapy. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - April 29, 2015 Category: Cancer & Oncology Source Type: research

Safety and feasibility of laparoscopic colo-rectal surgery for cancer at a tertiary center in a developing country: Egypt as an example
Conclusion Laparoscopic colorectal surgery for cancer in developing countries could be safe and feasible. Safe reuse of disposable expensive parts of some laparoscopic instruments could help in propagation of this technique in developing countries. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - April 25, 2015 Category: Cancer & Oncology Source Type: research

Clinical significance of anaplasia in childhood rhabdomyosarcoma
Conclusions The frequency of anaplasia in pediatric patients with rhabdomyosarcoma in our study was 17.1%. The presence of anaplasia had statistically significant worse clinical outcome. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - April 24, 2015 Category: Cancer & Oncology Source Type: research

Impact of imatinib interruption and duration of prior hydroxyurea on the treatment outcome in patients with chronic myeloid leukemia: Single institution experience
Conclusion Duration of prior hydroxyurea had no impact on response or progression free survival, while patients regular on imatinib had statistically significant difference with respect to major molecular response, complete molecular response and progression free survival compared to those who had periods of drug interruption, thus we need more governmental support to supply the drug without interruption to improve the outcome of therapy. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - April 14, 2015 Category: Cancer & Oncology Source Type: research

Diagnostic criteria of well differentiated thyroid tumor of uncertain malignant potential; a histomorphological and immunohistochemical appraisal
Conclusion The constellations of both major and minor criteria of malignancy are important clues for WDT-UMP diagnosis which could be ascertained by CK 19 immunostaining. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - March 21, 2015 Category: Cancer & Oncology Source Type: research

Long term survival with the combination of interferon and chemotherapy in metastatic melanoma
Publication date: Available online 12 March 2015 Source:Journal of the Egyptian National Cancer Institute Author(s): Bülent Karagöz , Oğuz Bilgi , Alpaslan Özgün , Levent Emirzeoğlu , Serkan Çelik , Ahmet Özet The prognosis of metastatic melanoma is poor. Pre-targeted treatment era, the combination of interferon-α (IF-α) plus chemotherapy had been used and have generally short response duration. Herein, we present a metastatic melanoma case that achieved long-term durable complete response (CR) IF-α plus chemotherapy and IF-α maintenance therapy and had lower Regulatory T (Treg) cells. A fifty-year ol...
Source: Journal of the Egyptian National Cancer Institute - March 13, 2015 Category: Cancer & Oncology Source Type: research

Exosomal protein interactors as emerging therapeutic targets in urothelial bladder cancer
Conclusions The importance of identifying interactors is that that they can be used as targets for therapy, for example, using Bevacizumab (avastin – an angiogenesis inhibitor) against NF2 to inhibit protein–protein interactions will inhibit tumor growth and progression by hindering the exosome biogenesis. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - February 26, 2015 Category: Cancer & Oncology Source Type: research

End-of-life palliative chemotherapy: Where do we stand?
Conclusion In our center; at the end of life, there is a gradual increase in the number of patients receiving chemotherapy which significantly increased cancer patients’ odds without clear predictive factors associated with its use, which calls into question the benefits of PCT in terminally ill cancer patients. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - February 26, 2015 Category: Cancer & Oncology Source Type: research

Holocord low grade astrocytoma – Role of radical irradiation and chemotherapy
We describe a case of a 14-year-old girl with holocord astrocytoma extending from cervicomedullary junction till lumbar spine, who recovered full neurological function following radical irradiation of entire spine followed by temozolomide-based chemotherapy. No grade 3/4 bone marrow morbidity was seen. Five years following treatment, she maintained normal neurological function and apparently normal pubertal and skeletal growth despite residual disease visible on imaging. Literature review of existing reports of holocord astrocytomas highlighting management and outcome is presented. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - February 22, 2015 Category: Cancer & Oncology Source Type: research

Prevalence and chemotherapy-induced reactivation of occult hepatitis B virus among hepatitis B surface antigen negative patients with diffuse large B-cell lymphoma: Significance of hepatitis B core antibodies screening
Conclusion The study concluded that anti-HBc screening is mandatory before chemotherapy. HBsAg-negative/anti-HBc-positive patients should be closely observed for signs of HBV reactivation through the regular monitoring of ALT. Prophylaxis lamivudine is recommended for anti-HBc positive patients before chemotherapy. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - February 22, 2015 Category: Cancer & Oncology Source Type: research

Oesophageal perforation during neo-adjuvant brachytherapy for oesophageal squamous cell carcinoma
Publication date: Available online 21 February 2015 Source:Journal of the Egyptian National Cancer Institute Author(s): Maryam H. Esfehani , Habibollah Mahmoodzadeh , Ramesh Omranipour Neo-adjuvant brachytherapy (NBT) for oesophageal cancer is under rapid development in recent years and more reports are required to elucidate its complications and drawbacks. Here, we report a case treated for NBT whose oesophagus was perforated during the procedure and mention necessary precautions to avoid it. A 73year old male whose upper gastrointestinal endoscopy showed a lesion extending from 29cm to 33cm of the incisors with a ...
Source: Journal of the Egyptian National Cancer Institute - February 22, 2015 Category: Cancer & Oncology Source Type: research

Radiation induced depigmentation disorder in two patients with breast cancer: Exploring a rare accompaniment
Publication date: Available online 21 February 2015 Source:Journal of the Egyptian National Cancer Institute Author(s): Ahitagni Biswas , Pritee B. Chaudhari , Pramod Kumar Julka , Goura Kishor Rath Radiation induced depigmentation disorder is a rare accompaniment. We herein report two patients of bilateral breast cancer developing depigmentation disorder, initially confined to the radiation portal with subsequent generalization within few months of completion of whole breast radiotherapy. Both these patients had no prior history of vitiligo or other autoimmune disorder. This brief report highlights the importance ...
Source: Journal of the Egyptian National Cancer Institute - February 22, 2015 Category: Cancer & Oncology Source Type: research