Journal of the Egyptian National Cancer Institute This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

An accelerated hypofractionated schedule with a daily concomitant boost after breast conservation surgery: the feasibility and toxicity
Conclusions Accelerated hypofractionated radiotherapy for early breast cancer with concomitant electron boost seems to be feasible providing consistent clinical results with acceptable toxicity profile. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - January 29, 2016 Category: Cancer & Oncology Source Type: research

Corrigendum to “Outcome of pediatric parameningeal rhabdomyosarcoma. The Children Cancer Hospital, Egypt experience” [J. Egyptian Natl. Cancer Inst. 25 (2013) 79–86]
Publication date: Available online 13 January 2016 Source:Journal of the Egyptian National Cancer Institute Author(s): Hany Abdel Rahman, Mohamed Sedky, Inas Mohsen, Hala Taha, Iman Loaye, Mohamed S. Zaghloul, Madiha El Wakeel, Rania M. Labib (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - January 14, 2016 Category: Cancer & Oncology Source Type: research

Molecular classification of colorectal cancer: Current perspectives and controversies
Conclusion For CRC, a broad molecular classification is “still missing”. There is a real hope that the evolving application of molecular techniques to diagnosis, risk-stratification and management of CRC will be translated to reduce disease burden and improve the survival. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - January 12, 2016 Category: Cancer & Oncology Source Type: research

The role of Napsin-A and Desmocollin-3 in classifying poorly differentiating non-small cell lung carcinoma
Conclusion Napsin-A, and Desmocollin-3 were sensitive and specific markers for the diagnosis of AC and SCC, respectively. Both markers allowed classification of 54/60 cases into either AC or SCC. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - December 20, 2015 Category: Cancer & Oncology Source Type: research

Immunohistochemical analysis of O6-methylguanine-DNA methyltransferase (MGMT) protein expression as prognostic marker in glioblastoma patients treated with radiation therapy with concomitant and adjuvant Temozolomide
Conclusions MGMT expression was identified as positive prognostic factor in patients with newly diagnosed glioblastoma who underwent surgical resection followed by adjuvant radiotherapy and concomitant oral TMZ chemotherapy (the Stupp protocol). (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - December 11, 2015 Category: Cancer & Oncology Source Type: research

Brain abscess mimicking brain metastasis in breast cancer
Publication date: Available online 23 November 2015 Source:Journal of the Egyptian National Cancer Institute Author(s): Pooja Khullar, Niloy R. Datta, Inderjeet Kaur Wahi, Sabeena Kataria 61year old female presented with chief complaints of headache for 30days, fever for 10days, altered behavior for 10days and convulsion for 2days. She was diagnosed and treated as a case of carcinoma of left breast 5years ago. MRI brain showed a lobulated lesion in the left frontal lobe. She came to our hospital for whole brain radiation as a diagnosed case of carcinoma of breast with brain metastasis. Review of MRI brain scan,...
Source: Journal of the Egyptian National Cancer Institute - November 23, 2015 Category: Cancer & Oncology Source Type: research

Invasive lobular carcinoma of the male breast: A rare histology of an uncommon disease
We report a case of locally advanced lobular carcinoma of breast in a 60year old male. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - November 1, 2015 Category: Cancer & Oncology Source Type: research

Detection of human mammaglobin A mRNA in peripheral blood of breast cancer patients before treatment and association with metastasis
Conclusion This study provides additional evidence of the presence of MGA in the peripheral blood of breast cancer patients, and its applicability as an efficient biomarker for breast cancer (High specificity and PPV). To our knowledge, this is the first study to assess the expression of MGA mRNA in peripheral blood obtained from the Brazilian population. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - October 17, 2015 Category: Cancer & Oncology Source Type: research

Clinical presentation of intraocular retinoblastoma; 5-year hospital-based registry in Egypt
Conclusion In Egypt, retinoblastoma patients present more frequently with advanced disease. There is an ever-increasing need to develop a national team dedicated to studying disease significance and formulating a national awareness program. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - October 17, 2015 Category: Cancer & Oncology Source Type: research

Relationship of obesity with serum concentrations of leptin, CRP and IL-6 in breast cancer survivors
Conclusions In conclusion, high leptin levels and alteration in acute phase proteins in obese patients may exaggerate the inflammation status. As inflammation has the potential to increase the susceptibility of the patients to metastasis development, it is necessary to decline its rate. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - October 13, 2015 Category: Cancer & Oncology Source Type: research

Targeted radiotherapy potentiates the cytotoxicity of a novel anti-human DR5 monoclonal antibody and the adenovirus encoding soluble TRAIL in prostate cancer
Publication date: Available online 16 September 2015 Source:Journal of the Egyptian National Cancer Institute Author(s): Waleed Arafat, Tong Zhou, George E. Naoum, Donald J. Buchsbaum TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) induces a death signal following binding to death receptors (DR4, DR5). We have developed a novel anti-human DR-5 monoclonal antibody (TRA-8) and adenoviral encoding TRAIL (Ad/TRAIL). Herein, we are testing the combined effect of radiotherapy and TRA-8 or Ad TRAIL in prostate cancer cells. Human prostate cancer cell lines LnCap, PC-3 and DU145 were used in this study....
Source: Journal of the Egyptian National Cancer Institute - September 17, 2015 Category: Cancer & Oncology Source Type: research

Radiation induced liver disease: A clinical update
Publication date: Available online 20 August 2015 Source:Journal of the Egyptian National Cancer Institute Author(s): R. Benson, R. Madan, R. Kilambi, S. Chander Radiation-induced liver disease (RILD) or radiation hepatitis is a sub-acute form of liver injury due to radiation. It is one of the most dreaded complications of radiation which prevents radiation dose escalation and re-irradiation for hepatobiliary or upper gastrointestinal malignancies. This complication should be kept in mind whenever a patient is planned for irradiation of these malignancies. Although, incidence of RILD is decreasing due to better...
Source: Journal of the Egyptian National Cancer Institute - August 21, 2015 Category: Cancer & Oncology Source Type: research

Radiation induced heart disease: Pathogenesis, management and review literature
Publication date: Available online 18 August 2015 Source:Journal of the Egyptian National Cancer Institute Author(s): R. Madan, R. Benson, D.N. Sharma, P.K. Julka, G.K. Rath Radiation therapy (RT) is a very important part of multimodality cancer therapy. Addition of RT improves survival in many cancers, but there are some accompaniments of radiation. One of them is radiation induced heart disease (RIHD). RT for mediastinal lymphoma, breast, lung and oesophageal cancer is associated with the development of RIHD. The problem can be intensified with the addition of chemotherapy. Therapeutic modalities for RIHD a...
Source: Journal of the Egyptian National Cancer Institute - August 19, 2015 Category: Cancer & Oncology Source Type: research

Adjuvant radiotherapy in the treatment of gall bladder carcinoma: What is the current evidence
Publication date: Available online 8 August 2015 Source:Journal of the Egyptian National Cancer Institute Author(s): Supriya Mallick, Rony Benson, K.P. Haresh, P.K. Julka, G.K. Rath Gall bladder carcinoma (GBC) is considered the fifth most common one of the most aggressive gastro intestinal tract malignancies. Owing to their large incidence randomised controlled trials have hardly been conducted to look into their optimum treatment. Over the years surgical resection has been considered the only curative treatment of these tumors. However, the outcome still remains guarded. The predominant pattern of failure i...
Source: Journal of the Egyptian National Cancer Institute - August 9, 2015 Category: Cancer & Oncology Source Type: research

Intracranial fibrosarcoma treated with adjuvant radiation and temozolomide: Report of a case and review of all published cases
Conclusion Fibrosarcoma is a rare disease with dismal prognosis. Surgery remains the cornerstone of therapy. Radiation confers long term disease control and survival. Chemotherapy needs to be evaluated for these tumours to improve survival. (Source: Journal of the Egyptian National Cancer Institute)
Source: Journal of the Egyptian National Cancer Institute - August 4, 2015 Category: Cancer & Oncology Source Type: research