Radiation induced liver disease: A clinical update

Publication date: Available online 20 August 2015 Source:Journal of the Egyptian National Cancer Institute Author(s): R. Benson, R. Madan, R. Kilambi, S. Chander Radiation-induced liver disease (RILD) or radiation hepatitis is a sub-acute form of liver injury due to radiation. It is one of the most dreaded complications of radiation which prevents radiation dose escalation and re-irradiation for hepatobiliary or upper gastrointestinal malignancies. This complication should be kept in mind whenever a patient is planned for irradiation of these malignancies. Although, incidence of RILD is decreasing due to better knowledge of liver tolerance, improved investigation modalities and modern radiation delivery techniques, treatment options are still limited. In this review article, we have focussed on patho-physiology, risk factors, prevention and management of RILD.
Source: Journal of the Egyptian National Cancer Institute - Category: Cancer & Oncology Source Type: research