Prognostic value of IDH1 mutations identified with PCR-RFLP assay in acute myeloid leukemia patients

Conclusion IDH1 mutations are recurring genetic alterations in AML and they may have unfavorable impact on clinical outcome in adult AML. The PCR-RFLP method allows for a fast, inexpensive, and sensitive method for the detection of IDH1 mutations in AML.
Source: Journal of the Egyptian National Cancer Institute - Category: Cancer & Oncology Source Type: research