Improving overall survival with post-mastectomy radiotherapy in a group of early-stage breast cancer: the number of negative lymph nodes sufficient to eliminate post-mastectomy radiotherapy
ConclusionAccording to the results of the current study on node-negative T1-T2 breast cancer patients, PMRT can overcome the inferior outcome of a suboptimal dissection and improve OS and is therefore recommended as a cutoff point if less than 4 nodes have been examined. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - August 30, 2016 Category: Cancer & Oncology Source Type: research
The impact of weight loss on setup accuracy for head and neck cancer patients in the era of image guided radiation therapy
ConclusionsIn the era of daily KV imaging for head and neck cancer, minimal shifts are needed despite significant weight loss. When weight loss is present, therapists and physicians should pay most attention to the LR dimension to ensure accurate treatment setup. This study suggests despite significant weight loss, daily KV imaging offers a high fidelity and reproducibility. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - August 23, 2016 Category: Cancer & Oncology Source Type: research
Long-term outcomes of stereotactic body radiation therapy (SBRT) with fiducial tracking for inoperable stage I non-small cell lung cancer (NSCLC)
ConclusionsDespite reduced treatment margins and lack of patient immobilization, SBRT with fiducial-based tumor tracking achieves clinically comparable long-term outcomes to other linac-based SBRT approaches. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - August 19, 2016 Category: Cancer & Oncology Source Type: research
Novel predictors of esophageal toxicity with stereotactic body radiation therapy for central lung tumors
ConclusionsPrevious thoracic RT, multiple-site irradiation, and percent esophageal overlap with 39 and 50 Gy isodose lines were most significantly associated with ET. These predictive factors can risk stratify SBRT patients for ET, and the dosimetric factors should be considered in treatment planning to decrease the risk of ET. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - August 16, 2016 Category: Cancer & Oncology Source Type: research
Changes in quality of life after radiation therapy for localized prostate cancer after dissemination of intensity modulated radiation therapy
ConclusionsHRQOL as measured by mental component scores were improved among prostate cancer patients in the era of IMRT compared to prior. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - August 9, 2016 Category: Cancer & Oncology Source Type: research
A comparison of dosimetric parameters in PET-based active bone marrow volume and total bone volume in prediction of hematologic toxicity in cervical cancer patients treated with chemoradiation
ConclusionA lower volume of ABM at a baseline (<1201 mL) was highly predictive of grade 3+ hematologic toxicity. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - August 9, 2016 Category: Cancer & Oncology Source Type: research
Dosimetric verification of dental stent efficacy in head and neck radiation therapy using modern radiation therapy techniques: quality of life and treatment compliance implications
ConclusionsThis approximately 40 % dose reduction implies that patients’ oral mucosae adjacent to dental fixtures could receive more than 100 Gy during a course of definitive radiotherapy to the head and neck without dental stents. In this era of increasing IMRT/VMAT utilization, our results emphasize the value of stent use to improve morbidity and reduce treatment breaks for patients undergoing head and neck radiotherapy. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - August 7, 2016 Category: Cancer & Oncology Source Type: research
Pancreatic cancer: a review with future directions
< h3 class= " a-plus-plus " > Abstract < /h3 > < p class= " a-plus-plus " > Pancreatic cancer continues to be one of the most deadly cancers in the USA, causing over 41,780 deaths per year. Due to the nonspecific signs and symptoms of the disease, it typically presents late in the disease course, making curative therapy very difficult. Despite great improvements in imaging, such as CT, MRI/MRCP, and PET scans, there is still no truly effective screening method, and lesions are often found at sizes that are not amenable to resection. Major improvements have also been made in treatment options for pancreatic cancer, such as ...
Source: Journal of Radiation Oncology - July 29, 2016 Category: Cancer & Oncology Source Type: research
A new imaging/therapy platform by using external radionuclide ( 192 Ir) part 2: data acquisition and analysis for breast imaging
Conclusion < /h3 > < p class= " a-plus-plus " > The < sup class= " a-plus-plus " > 192 < /sup > Ir radionuclide can be used as a possible external radiation source for breast imaging. This study provides the evidence that building a new imaging/therapy dual-function platform using a single < sup class= " a-plus-plus " > 192 < /sup > Ir source is feasible. < /p > < /span > (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - July 26, 2016 Category: Cancer & Oncology Source Type: research
Three-dimensional conformal planning using low-segment multi-criteria optimization for hippocampal avoidance whole brain radiotherapy
Conclusion
All dosimetric parameters of MCO-3D plans met the criteria of at least acceptable variation per RTOG 0933. The statistic comparison results showed that there were some minor statistical differences between MCO-IMRT and MCO-3D; however, the biological difference was not of clinical importance. This may be helpful in cases where there is denial of patient’s medical insurance coverage due to the use of IMRT for HA-WBRT. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - July 15, 2016 Category: Cancer & Oncology Source Type: research
Gleason score and the risk of cause-specific and all-cause mortality following radiation with or without 6 months of androgen deprivation therapy for men with unfavorable-risk prostate cancer
Conclusion
While ADT reduced PCSM risk overall, survival was not prolonged in men with GS 9/10 due to ADT-driven increased OCM, which supports the hypothesis that older men with significant comorbidity may not experience prolonged survival when ADT is added to RT. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - June 28, 2016 Category: Cancer & Oncology Source Type: research
Contemporary management of large-volume arteriovenous malformations: a clinician ’s review
< h3 class= " a-plus-plus " > Abstract < /h3 > < p class= " a-plus-plus " > Arteriovenous malformations (AVMs) represent a heterogeneous group of lesions, and as such, there exist several treatment options and approaches depending on size, location, grading, and symptoms. Large-volume AVMs represent a particularly challenging subset of AVMs with controversy over the very classification with definitions based on size, volume, and Spetzler-Martin grade. With regards to treatment paradigms, the natural history of these lesions is an important foundation upon which management principles have been built. At this time, managemen...
Source: Journal of Radiation Oncology - June 26, 2016 Category: Cancer & Oncology Source Type: research
Contemporary management of large-volume arteriovenous malformations: a clinician’s review
Abstract
Arteriovenous malformations (AVMs) represent a heterogeneous group of lesions, and as such, there exist several treatment options and approaches depending on size, location, grading, and symptoms. Large-volume AVMs represent a particularly challenging subset of AVMs with controversy over the very classification with definitions based on size, volume, and Spetzler-Martin grade. With regards to treatment paradigms, the natural history of these lesions is an important foundation upon which management principles have been built. At this time, management options range from observation with medical man...
Source: Journal of Radiation Oncology - June 26, 2016 Category: Cancer & Oncology Source Type: research
Predictors of post-treatment symptomatic pneumonitis in lung SBRT patients through decision tree analysis
Conclusion
Based on this retrospective analysis, post-treatment symptomatic pneumonitis was successfully predicted by this developed decision tree using 4 readily available clinical and dosimetric factors. Using this decision tree, it is possible to identify lung SBRT patients at higher risk of developing symptomatic pneumonitis. These findings warrant validation with an external dataset and subsequent testing in a prospective study. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - June 2, 2016 Category: Cancer & Oncology Source Type: research
The proceedings of acro 2016
(Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - May 13, 2016 Category: Cancer & Oncology Source Type: research
