Three-dimensional conformal planning using low-segment multi-criteria optimization for hippocampal avoidance whole brain radiotherapy

Conclusion All dosimetric parameters of MCO-3D plans met the criteria of at least acceptable variation per RTOG 0933. The statistic comparison results showed that there were some minor statistical differences between MCO-IMRT and MCO-3D; however, the biological difference was not of clinical importance. This may be helpful in cases where there is denial of patient’s medical insurance coverage due to the use of IMRT for HA-WBRT.
Source: Journal of Radiation Oncology - Category: Cancer & Oncology Source Type: research