Whiteboard patient tracking system improves radiation oncology treatment planning workflow
ConclusionsWhiteboard implementation resulted in a significant decrease in time from CT simulation date to contour approval and plan approval. When used effectively, an automated whiteboard system facilitates improved workflow. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - May 5, 2019 Category: Cancer & Oncology Source Type: research
Changes in prostate-specific antigen midway through salvage radiotherapy may be associated with long-term outcomes
ConclusionsPSA changes by the midpoint of SRT predict long-term prostate cancer control with increases in PSA associated with decreased freedom from disease progression. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - May 1, 2019 Category: Cancer & Oncology Source Type: research
Lymphopenia as a predictor of survival in chemoradiation-treated stage III non-small-cell lung cancer (NSCLC): a multi-center retrospective analysis
ConclusionsHD RT in stage III NSCLC patients is associated with worse survival. Lower nadir lymphocyte counts, independent of dose of radiation, were not associated with decrease in survival. These findings need further validation in larger studies and in patients treated with immune therapy. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - April 28, 2019 Category: Cancer & Oncology Source Type: research
Adjuvant chemoradiation in resected gallbladder cancer: a prognostic index model for predicting overall survival
ConclusionOverall results after multimodality treatment of GBC are promising. A risk model was generated to determine a prognostic index for individual patients with GBC. Classification of risk factors for death has contributed to propose a prognostic index that could allow us to guide risk-adapted tailored treatment. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - March 25, 2019 Category: Cancer & Oncology Source Type: research
Correction to: Stereotactic body radiation therapy for non-small cell lung cancer patients with prior history of thoracic surgery and/or radiation therapy: the influence of smoking, size, and central location on risk of complications
The article Stereotactic body radiation therapy for non-small cell lung cancer patients with prior history of thoracic surgery and/or radiation therapy: the influence of smoking, size, and central location on risk of complications. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - March 22, 2019 Category: Cancer & Oncology Source Type: research
Comparison of deep inspiration breath hold and free breathing technique in left breast cancer irradiation: a dosimetric evaluation in 40 patients
ConclusionOur study confirms the DIBH technique advantage in reducing cardiac and pulmonary doses for tangentially treated left-sided breast cancer patients. Further research is warranted to evaluate potential long-term clinical implications of these relevant dosimetry results. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - March 18, 2019 Category: Cancer & Oncology Source Type: research
Reconstructed and real proton radiographs for image-guidance in proton beam therapy
AbstractOne of the major challenges to proton beam therapy at this time is the uncertainty of the true range of a clinical treatment proton beam as it traverses the various tissues and organs in a human body. This uncertainty necessitates the addition of greater “margins” to the planning target volume along the direction of the beam to ensure safety and tumor target coverage.Proton radiography holds promise as both an image-guidance method for proton beam therapy and as a means of estimating particle beam range in the clinic. In this brief report, we present some of the first real and reconstructed proton radiographs u...
Source: Journal of Radiation Oncology - March 18, 2019 Category: Cancer & Oncology Source Type: research
Use of the neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) for prognostication of patients with early-stage non-small cell lung cancer (NSCLC) treated with stereotactic body radiation therapy (SBRT): a systematic review
ConclusionNLR and PLR appear to be relevant prognostic factors for OS following lung SBRT in stage I NSCLC. They may serve as accessible and inexpensive tests to aid in clinical decision-making but prospective validation is necessary. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - March 18, 2019 Category: Cancer & Oncology Source Type: research
Prostate radiotherapy effects on testosterone levels: an empirical investigation
ConclusionEmpirical evidence does not support the hypothesis that incidental exposure of the testicular Leydig cells from scattered photons and/or daily portal imaging affects testosterone levels. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - March 17, 2019 Category: Cancer & Oncology Source Type: research
Targeted therapy combined with thoracic radiotherapy for non-small cell lung cancer
ConclusionsIn this review, we summarize the recent literature about the use of molecularly targeted agents with concurrent RT in NSCLC patients. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - March 13, 2019 Category: Cancer & Oncology Source Type: research
Rectal wall delineation in patients with a rectal displacement device in place during prostate cancer radiotherapy
(Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - March 6, 2019 Category: Cancer & Oncology Source Type: research
Reduced acute and late toxicities with intensity-modulated radiation therapy compared to three-dimensional conformal radiation therapy in post-operative gastric cancer
ConclusionsUse of IMRT in post-operative gastric cancer is associated with reduced acute and late toxicities. Consideration should be given for prospective evaluation in the future. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - February 14, 2019 Category: Cancer & Oncology Source Type: research
Radiotherapy for parotid malignancies: patterns of care and impact on overall survival
ConclusionsOur data suggests that PORT was associated with improved survival. Additionally, some subgroups may receive additional benefit and patients with small (T1), low-grade disease may be able to forgo PORT. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - February 2, 2019 Category: Cancer & Oncology Source Type: research
Volume effects in radiosurgical spinal cord dose tolerance: how small is too small?
ConclusionsDmax has greater variability compared to D0.03 cc, D0.1 cc, and D1 cc, potentially creating risks when used for guidance for spinal cord. D0.03 cc may be an attractive alternative with higher reliability while its limits could be obtained by scaling the reported Dmax limit by a factor of 0.93. This may help guide treatment planning and aid in discovering true dose constraints for spine SBRT. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - January 31, 2019 Category: Cancer & Oncology Source Type: research
Ductal carcinoma in situ (DCIS) breast cancer treated with 3-week accelerated hypofractionated whole-breast radiation therapy and concomitant boost
ConclusionThe HF schedule with CB in DCIS patients is well tolerated and associated with excellent clinical outcomes. This schedule affords the benefit of delivering higher dose to the lumpectomy site without protracting overall treatment time. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - January 26, 2019 Category: Cancer & Oncology Source Type: research
