The use of stereotactic radiosurgery for benign spinal tumors: single institution experience
ConclusionThe results of SRS for benign tumors of the spine appear to be promising, and as a result SRS may have a role in treating benign spinal tumors for patients who are not surgical candidates. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - March 4, 2018 Category: Cancer & Oncology Source Type: research
Assessment of contouring resource use and awareness of contouring guidelines among radiation oncologists
ConclusionThis study provides information to guide further development and implementation of contouring resources, with radiation oncologists preferring resources that are atlas-based and can be accessed quickly and easily. Both self-reported and objectively tested awareness of consensus contouring guidelines was low, reflecting a need for better guideline dissemination. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - February 8, 2018 Category: Cancer & Oncology Source Type: research
Pediatric high-grade glioma: a review of biology, prognosis, and treatment
AbstractThe incidence of high-grade gliomas (HGGs) in children is significantly lower than in adults, with less than 400 children diagnosed every year in the USA. While the histopathology of HGGs in children is very similar to those in adults, their biology is very different. Recent studies have led to an exponential increase in our understanding of the biology of these tumors, with the identification of distinct epigenetic subtypes, each with characteristic clinical and molecular profiles. The 2016 WHO classification of central nervous system tumors has recognized the most common subtype, with the poorest prognosis —“...
Source: Journal of Radiation Oncology - February 3, 2018 Category: Cancer & Oncology Source Type: research
Association of conformality index and post-treatment radiation pneumonitis in early-stage non-small cell lung cancer treated with stereotactic body radiotherapy
ConclusionsAdhering to recommended CI50 values does not significantly decrease the incidence of clinically significant RP in patients with NSCLC treated with SBRT. To the authors ’ knowledge, this observation has not been published previously. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - January 18, 2018 Category: Cancer & Oncology Source Type: research
Does histology dictate outcomes of locally advanced rectal adenocarcinoma with complete pathological response following neoadjuvant chemoradiation?
ConclusionHistological subtype does not affect the long-term outcomes in patients who achieve pathological complete response to preoperative chemoradiation. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - January 8, 2018 Category: Cancer & Oncology Source Type: research
Comparison between CT- and MRI-derived head and neck cancer target volumes using an integrated MRI-tri- 60 Co teletherapy device
ConclusionSignificant differences in GTV extent were noted between MRI- and CT-derived ViewRay images. The implications for treatment planning are discussed. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - January 4, 2018 Category: Cancer & Oncology Source Type: research
Effect of BioZorb ® surgical marker placement on post-operative radiation boost target volume
ConclusionThe BioZorb ® arm showed statistically significant reductions in CTV and PTV but not ipsilateral lung or heart irradiation. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - January 3, 2018 Category: Cancer & Oncology Source Type: research
Preoperative short-course radiotherapy in rectal cancer patients: results and prognostic factors
ConclusionsPreoperative short-course radiotherapy followed by total mesorectal excision and adjuvant chemotherapy allows to achieve excellent local control and favorable survival rates. The treatment-induced toxicity is acceptable. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - December 20, 2017 Category: Cancer & Oncology Source Type: research
Intraoperative radiation therapy as part of planned monotherapy for early-stage breast cancer
ConclusionsThe results of our series suggest the feasibility of utilizing IORT in a community-based cancer center with a high degree of local control, and patient satisfaction with regard to cosmesis. While the results of this series suggest that IORT may be a promising modality, longer follow-up is warranted to better understand exactly which clinicopathological features can predict long-term locoregional disease control. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - December 19, 2017 Category: Cancer & Oncology Source Type: research
Prognostic factors affecting overall survival and local control in meningioma patients treated with radiotherapy or combined radiotherapy and surgery
ConclusionsWe confirm that meningioma grade is prognostic for OS and LC. Gender and PR status were prognostic with respect to LC, with significantly better LC in women and patients with strong PR expression. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - December 17, 2017 Category: Cancer & Oncology Source Type: research
Image-guided adaptive radiotherapy improves acute toxicity during intensity-modulated radiation therapy for head and neck cancer
ConclusionThe use of an image-guided adaptive radiotherapy strategy reduced the incidence of high-grade skin toxicity and oral mucositis in the acute setting. Further studies are needed to better define which subset of patients may benefit the most. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - December 9, 2017 Category: Cancer & Oncology Source Type: research
Pre-treatment peer-review: enhancing value through increased efficiency and effectiveness of radiation oncology peer review
ConclusionThe addition of comprehensive pre-treatment peer review proved valuable and effective. The introduction of pre-treatment peer review resulted in an almost 50% reduction in on-treatment chart round changes. This reduction provides value in both patient safety and clinical efficiency. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - December 8, 2017 Category: Cancer & Oncology Source Type: research
Overcoming barriers to radiotherapy in at-risk urban populations: primary language as a driver of initiation disparity
ConclusionPatient primary language does not have an effect on radiotherapy initiation time in an urban safety net hospital. At-risk urban patient populations face barriers to treatment that may confound previously reported differences in English- and non-English-speaking patients. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - November 8, 2017 Category: Cancer & Oncology Source Type: research
Stereotactic radiosurgery for multiple myeloma of the spine
ConclusionSRS appears to be effective in the treatment of MM of the spine. To the best of our knowledge, this is the largest such experience reported. (Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - November 7, 2017 Category: Cancer & Oncology Source Type: research
First Annual Report of the Resident Committee of the American College of Radiation Oncology
(Source: Journal of Radiation Oncology)
Source: Journal of Radiation Oncology - October 24, 2017 Category: Cancer & Oncology Source Type: research
