Gleason score and the risk of cause-specific and all-cause mortality following radiation with or without 6 months of androgen deprivation therapy for men with unfavorable-risk prostate cancer

Conclusion While ADT reduced PCSM risk overall, survival was not prolonged in men with GS 9/10 due to ADT-driven increased OCM, which supports the hypothesis that older men with significant comorbidity may not experience prolonged survival when ADT is added to RT.
Source: Journal of Radiation Oncology - Category: Cancer & Oncology Source Type: research