PDQ (Physician Data Query)
(Source: JNCI)
Source: JNCI - September 13, 2016 Category: Cancer & Oncology Tags: NEWS Source Type: research
Erratum
(Source: JNCI)
Source: JNCI - September 13, 2016 Category: Cancer & Oncology Tags: ERRATUM Source Type: research
Relationship Between Increased Fucosylation and Metastatic Potential in Colorectal Cancer
Conclusions: Thus, fucose-bound liposomes carrying anticancer drugs provide a new strategy for the treatment of CRC patients. (Source: JNCI)
Source: JNCI - September 13, 2016 Category: Cancer & Oncology Authors: Osuga, T., Takimoto, R., Ono, M., Hirakawa, M., Yoshida, M., Okagawa, Y., Uemura, N., Arihara, Y., Sato, Y., Tamura, F., Sato, T., Iyama, S., Miyanishi, K., Takada, K., Hayashi, T., Kobune, M., Kato, J. Tags: ARTICLES Source Type: research
Erratum
(Source: JNCI)
Source: JNCI - September 13, 2016 Category: Cancer & Oncology Tags: ERRATUM Source Type: research
Table of Contents
(Source: JNCI)
Source: JNCI - September 13, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research
Subscription
(Source: JNCI)
Source: JNCI - September 13, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research
Editorial Board
(Source: JNCI)
Source: JNCI - September 13, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research
Cover
(Source: JNCI)
Source: JNCI - September 13, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research
Selective Activation of Anticancer Chemotherapy by Cancer-Associated Fibroblasts in the Tumor Microenvironment
Conclusions: The demonstration of selective activation of PL-rGO by FAP on CAFs suggests that PL-rGO may serve as a tumor microenvironment–responsive anticancer chemotherapy system. (Source: JNCI)
Source: JNCI - September 10, 2016 Category: Cancer & Oncology Authors: Kim, M.-G., Shon, Y., Kim, J., Oh, Y.-K. Tags: Research Article Source Type: research
Effects of In Utero Exposure to Ethinyl Estradiol on Tamoxifen Resistance and Breast Cancer Recurrence in a Preclinical Model
Conclusions: Resistance to TAM may be preprogrammed by in utero exposure to high estrogen levels and mediated through reversible epigenetic alterations in genes associated with epithelial-mesenchymal transition and tumor immune responses. (Source: JNCI)
Source: JNCI - September 7, 2016 Category: Cancer & Oncology Authors: Hilakivi-Clarke, L., Wärri, A., Bouker, K. B., Zhang, X., Cook, K. L., Jin, L., Zwart, A., Nguyen, N., Hu, R., Cruz, M. I., de Assis, S., Wang, X., Xuan, J., Wang, Y., Wehrenberg, B., Clarke, R. Tags: Article Source Type: research
Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
Conclusions: Findings from this large prospective study support a role of oophorectomy for the prevention of premenopausal breast cancer in BRCA2, but not BRCA1 mutation carriers. These findings warrant further evaluation. (Source: JNCI)
Source: JNCI - September 5, 2016 Category: Cancer & Oncology Authors: Kotsopoulos, J., Huzarski, T., Gronwald, J., Singer, C. F., Moller, P., Lynch, H. T., Armel, S., Karlan, B., Foulkes, W. D., Neuhausen, S. L., Senter, L., Tung, N., Weitzel, J. N., Eisen, A., Metcalfe, K., Eng, C., Pal, T., Evans, G., Sun, P., Lubinski, J Tags: Article Source Type: research
Response
(Source: JNCI)
Source: JNCI - August 30, 2016 Category: Cancer & Oncology Authors: Spurdle, A. B., Domchek, S., Robson, M., Buys, S., Radice, P., de la Hoya, M., Devilee, P., Monteiro, A. N. A., Southey, M., Eccles, D., Couch, F. J., Goldgar, D. E., on behalf of all authors Tags: Response Source Type: research
RE: BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers
(Source: JNCI)
Source: JNCI - August 30, 2016 Category: Cancer & Oncology Authors: Arbustini, E., Sgarella, A., Ferrari, A., Grasso, D., Cassani, C., Lucioni, M., Di Giulio, G., Grasso, M. Tags: Correspondence Source Type: research
Adverse Clinical Outcome Associated With Mutations That Typify African American Colorectal Cancers
African Americans have the highest incidence and mortality from colorectal cancer (CRC) of any US racial group. We recently described a panel of 15 genes that are statistically significantly more likely to be mutated in CRCs from African Americans than in Caucasians (AA-CRC genes). The current study investigated the outcomes associated with these mutations in African American CRCs (AA-CRCs). In a cohort of 66 patients with stage I-III CRCs, eight of 27 CRCs with AA-CRC gene mutations (Mut+) developed metastatic disease vs only four of 39 mutation-negative (Mut-) cases (P = .03, Cox regression model with two-sided Wald test...
Source: JNCI - August 30, 2016 Category: Cancer & Oncology Authors: Wang, Z., Li, L., Guda, K., Chen, Z., Barnholtz-Sloan, J., Park, Y. S., Markowitz, S. D., Willis, J. Tags: Brief Communication Source Type: research
