Cancer Stem Cell Hypothesis Evolves With Emerging Research
(Source: JNCI)
Source: JNCI - April 28, 2016 Category: Cancer & Oncology Authors: Brower, V. Tags: News Source Type: research

Stat Bite Number of New Melanoma of the Skin Cases By Race/Ethnicity & Sex (2008-2012)
(Source: JNCI)
Source: JNCI - April 28, 2016 Category: Cancer & Oncology Tags: News Source Type: research

Fighting Cancer Resistance
(Source: JNCI)
Source: JNCI - April 28, 2016 Category: Cancer & Oncology Authors: Ullman, K. Tags: News Source Type: research

Prostate Cancer: A New Twist on Active Surveillance
(Source: JNCI)
Source: JNCI - April 28, 2016 Category: Cancer & Oncology Authors: Delude, C. Tags: News Source Type: research

HPV 16 and its variants: minor genome variations make a big difference
(Source: JNCI)
Source: JNCI - April 28, 2016 Category: Cancer & Oncology Authors: von Knebel Doeberitz, M. Tags: Solicited Editorial Source Type: research

Risk Stratification and Intrinsic Subtype Classification of Breast Cancer: a Multi-Parameter Test to Rule Them All?
(Source: JNCI)
Source: JNCI - April 28, 2016 Category: Cancer & Oncology Authors: Natrajan, R., Weigelt, B. Tags: Solicited Editorial Source Type: research

HPV16 Sublineage Associations With Histology-Specific Cancer Risk Using HPV Whole-Genome Sequences in 3200 Women
Conclusions: Specific HPV16 variant sublineages strongly influence risk of histologic types of precancer and cancer, and viral genetic variation may help explain its unique carcinogenic properties. (Source: JNCI)
Source: JNCI - April 28, 2016 Category: Cancer & Oncology Authors: Mirabello, L., Yeager, M., Cullen, M., Boland, J. F., Chen, Z., Wentzensen, N., Zhang, X., Yu, K., Yang, Q., Mitchell, J., Roberson, D., Bass, S., Xiao, Y., Burdett, L., Raine-Bennett, T., Lorey, T., Castle, P. E., Burk, R. D., Schiffman, M. Tags: Article Source Type: research

Comparing Breast Cancer Multiparameter Tests in the OPTIMA Prelim Trial: No Test Is More Equal Than the Others
Conclusions: Existing evidence on the comparative prognostic information provided by different tests suggests that current multiparameter tests provide broadly equivalent risk information for the population of women with estrogen receptor (ER)–positive breast cancers. However, for the individual patient, tests may provide differing risk categorization and subtype information. (Source: JNCI)
Source: JNCI - April 28, 2016 Category: Cancer & Oncology Authors: Bartlett, J. M. S., Bayani, J., Marshall, A., Dunn, J. A., Campbell, A., Cunningham, C., Sobol, M. S., Hall, P. S., Poole, C. J., Cameron, D. A., Earl, H. M., Rea, D. W., Macpherson, I. R., Canney, P., Francis, A., McCabe, C., Pinder, S. E., Hughes-Davies Tags: Article Source Type: research

Improved biopsy efficiency with MR/ultrasound fusion-guided prostate biopsy
(Source: JNCI)
Source: JNCI - April 28, 2016 Category: Cancer & Oncology Authors: Kim, E. H., Andriole, G. L. Tags: Editorial Source Type: research

Efficiency of Prostate Cancer Diagnosis by MR/Ultrasound Fusion-Guided Biopsy vs Standard Extended-Sextant Biopsy for MR-Visible Lesions
Conclusion: In men with MR-visible prostate lesions, targeted biopsy is more efficient than standard biopsy, diagnosing a similar number of cancer cases and more high-grade cases while sampling 56.1% fewer biopsy cores. (Source: JNCI)
Source: JNCI - April 28, 2016 Category: Cancer & Oncology Authors: Siddiqui, M. M., George, A. K., Rubin, R., Rais-Bahrami, S., Parnes, H. L., Merino, M. J., Simon, R. M., Turkbey, B., Choyke, P. L., Wood, B. J., Pinto, P. A. Tags: Article Source Type: research

Breast Density: More Than Meets the Eye
(Source: JNCI)
Source: JNCI - April 28, 2016 Category: Cancer & Oncology Authors: Kerlikowske, K., Vachon, C. M. Tags: Solicited Editorial Source Type: research

Racial Differences in Quantitative Measures of Area and Volumetric Breast Density
Conclusions: After accounting for age, BMI, and other risk factors, black women had higher breast density than white women across all quantitative measures previously associated with breast cancer risk. These results may have implications for risk assessment and screening. (Source: JNCI)
Source: JNCI - April 28, 2016 Category: Cancer & Oncology Authors: McCarthy, A. M., Keller, B. M., Pantalone, L. M., Hsieh, M.-K., Synnestvedt, M., Conant, E. F., Armstrong, K., Kontos, D. Tags: Article Source Type: research

Estrobolome Disparities May Lead To Developing Biomarkers That Could Mitigate Cancer Risk
(Source: JNCI)
Source: JNCI - April 21, 2016 Category: Cancer & Oncology Tags: Memo to the Media Source Type: research

Estrobolome Disparities May Lead To Developing Bimoarkers That Could Mitigate Cancer Risk
(Source: JNCI)
Source: JNCI - April 21, 2016 Category: Cancer & Oncology Tags: Memo to the Media Source Type: research

The Intestinal Microbiome and Estrogen Receptor-Positive Female Breast Cancer
The huge communities of residential microbes, including bacteria, viruses, Archaea, and Eukaryotes, that colonize humans are increasingly recognized as playing important roles in health and disease. A complex populous ecosystem, the human gastrointestinal (GI) tract harbors up to 1011 bacterial cells per gram of luminal content, whose collective genome, the gut metagenome, contains a vastly greater number of individual genes than the human genome. In health, the function of the microbiome might be considered to be in dynamic equilibrium with the host, exerting both local and distant effects. However, ‘disequilibrium&...
Source: JNCI - April 21, 2016 Category: Cancer & Oncology Authors: Kwa, M., Plottel, C. S., Blaser, M. J., Adams, S. Tags: Review Source Type: research