PDQ (Physician Data Query)
(Source: JNCI)
Source: JNCI - July 1, 2016 Category: Cancer & Oncology Tags: News Source Type: research
High Glycemic Index Associated With Increased Lung Cancer Risk
(Source: JNCI)
Source: JNCI - July 1, 2016 Category: Cancer & Oncology Authors: Rochman, S. Tags: News Source Type: research
Everolimus Effectively Treats Neuroendocrine Tumors of Gut and Lungs
(Source: JNCI)
Source: JNCI - July 1, 2016 Category: Cancer & Oncology Authors: Ullman, K. Tags: News Source Type: research
Deciding on Therapy: New Tools Factor In Cost of Care
(Source: JNCI)
Source: JNCI - July 1, 2016 Category: Cancer & Oncology Authors: McNeil, C. Tags: News Source Type: research
Genomic Analysis of Immune Cell Infiltrates Across 11 Tumor Types
Conclusions: These data support existing studies suggesting that in diverse tissue types, heterogeneous immune infiltrates are present and typically portend an improved prognosis. In some tumor types, BCR diversity was also associated with survival. Quantitative genomic signatures of immune cells warrant further testing as prognostic markers and potential biomarkers of response to cancer immunotherapy. (Source: JNCI)
Source: JNCI - June 21, 2016 Category: Cancer & Oncology Authors: Iglesia, M. D., Parker, J. S., Hoadley, K. A., Serody, J. S., Perou, C. M., Vincent, B. G. Tags: Article Source Type: research
Table_of_Contents
(Source: JNCI)
Source: JNCI - June 13, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research
Editorial_Board
(Source: JNCI)
Source: JNCI - June 13, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research
Cover
(Source: JNCI)
Source: JNCI - June 13, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research
Effect Modification by Time Since Blood Draw on the Association Between Circulating Fatty Acids and Prostate Cancer Risk
A recent meta-analysis suggested that circulating fatty acids do not play an important role in prostate carcinogenesis. We hypothesized that the relation between circulating fatty acids and prostate cancer (PCa) risk is modified by time between blood draw and diagnosis. We tested this hypothesis in a prospective case-control study of 476 PCa cases and matched control subjects nested in the Physicians’ Health Study. The previously reported associations between fatty acids and PCa in this cohort were dramatically stronger among men diagnosed 10 or more years after blood collection. Statistically significant effect modi...
Source: JNCI - June 12, 2016 Category: Cancer & Oncology Authors: Yang, M., Sesso, H. D., Colditz, G. A., Ma, J., Stampfer, M. J., Chavarro, J. E. Tags: Brief Communication Source Type: research
Molecularly Defined Adult Granulosa Cell Tumor of the Ovary: The Clinical Phenotype
The histopathologic features of adult granulosa cell tumors (AGCTs) are relatively nonspecific, resulting in misdiagnosis of other cancers as AGCT, a problem that has not been well characterized. FOXL2 mutation testing was used to stratify 336 AGCTs from three European centers into three categories: 1) FOXL2 mutant molecularly defined AGCT (MD-AGCT) (n = 256 of 336), 2) FOXL2 wild-type AGCT (n = 17 of 336), 3) misdiagnosed other tumor types (n = 63 of 336). All statistical tests were two-sided. The overall and disease-specific survival of the misdiagnosed cases was lower than in the MD-AGCTs (P < .001). The misdiagnosed...
Source: JNCI - June 12, 2016 Category: Cancer & Oncology Authors: McConechy, M. K., Färkkilä, A., Horlings, H. M., Talhouk, A., Unkila-Kallio, L., van Meurs, H. S., Yang, W., Rozenberg, N., Andersson, N., Zaby, K., Bryk, S., Bützow, R., Halfwerk, J. B. G., Hooijer, G. K. J., van de Vijver, M. J., Tags: Brief Communication Source Type: research
Germline CDKN2A Mutation Status and Survival in Familial Melanoma Cases
Conclusions: CDKN2Amut cases had statistically significantly worse survival than nonmelanoma cancers and, intriguingly, also from melanoma, compared with melanoma cases with no CDKN2A mutations. Further studies are required to elucidate possible mechanisms behind increased carcinogen susceptibility and the more aggressive melanoma phenotype in CDKN2A mutation carriers. (Source: JNCI)
Source: JNCI - June 9, 2016 Category: Cancer & Oncology Authors: Helgadottir, H., Höiom, V., Tuominen, R., Nielsen, K., Jönsson, G., Olsson, H., Hansson, J. Tags: Article Source Type: research
Sweetened beverage consumption linked to elevated risk of biliary tract and gallbladder cancer
(Source: JNCI)
Source: JNCI - June 7, 2016 Category: Cancer & Oncology Tags: Memo to the Media Source Type: research
Sweetened Beverage Consumption and Risk of Biliary Tract and Gallbladder Cancer in a Prospective Study
Conclusions: These findings support the hypothesis that high consumption of sweetened beverages may increase the risk of BTC, particularly gallbladder cancer. (Source: JNCI)
Source: JNCI - June 7, 2016 Category: Cancer & Oncology Authors: Larsson, S. C., Giovannucci, E. L., Wolk, A. Tags: Article Source Type: research
Stat Bite Number of New Cases of Pancreatic Cancer by Age Group (2008-2012)
(Source: JNCI)
Source: JNCI - June 1, 2016 Category: Cancer & Oncology Tags: News Source Type: research
Heterogeneous and Rare: Toward Histology-Specific Treatment of Soft-Tissue Sarcoma
(Source: JNCI)
Source: JNCI - June 1, 2016 Category: Cancer & Oncology Authors: Azvolinsky, A. Tags: news Source Type: research
