"P < 0.05" Might Not Mean What You Think: American Statistical Association Clarifies P Values
(Source: JNCI)
Source: JNCI - August 9, 2016 Category: Cancer & Oncology Authors: Grabowski, B. Tags: NEWS Source Type: research

Engineered T Cells Improve Pancreatic Cancer Outcomes in Mice
(Source: JNCI)
Source: JNCI - August 9, 2016 Category: Cancer & Oncology Authors: Fillon, M. Tags: NEWS Source Type: research

Table of Contents
(Source: JNCI)
Source: JNCI - August 9, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research

Subscription
(Source: JNCI)
Source: JNCI - August 9, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research

Editorial Board
(Source: JNCI)
Source: JNCI - August 9, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research

Cover
(Source: JNCI)
Source: JNCI - August 9, 2016 Category: Cancer & Oncology Tags: Cover / Standing Material Source Type: research

Long-term Outcome of an Organ Preservation Program After Neoadjuvant Treatment for Rectal Cancer
Conclusions: Organ preservation appears oncologically safe for selected rectal cancer patients with a cCR or near cCR after neoadjuvant chemoradiation when applying strict selection criteria and frequent follow-up, including endoscopy and MRI. The low colostomy rate and the good long-term functional outcome warrant discussing this option with the patient as an alternative to major surgery. (Source: JNCI)
Source: JNCI - August 9, 2016 Category: Cancer & Oncology Authors: Martens, M. H., Maas, M., Heijnen, L. A., Lambregts, D. M. J., Leijtens, J. W. A., Stassen, L. P. S., Breukink, S. O., Hoff, C., Belgers, E. J., Melenhorst, J., Jansen, R., Buijsen, J., Hoofwijk, T. G. M., Beets-Tan, R. G. H., Beets, G. L. Tags: Article Source Type: research

RE: HABP2 G534E Mutation in Familial Nonmedullary Thyroid Cancer
(Source: JNCI)
Source: JNCI - July 13, 2016 Category: Cancer & Oncology Authors: Simeone, P., Alberti, S. Tags: Correspondence Source Type: research

Eradication of Helicobacter pylori and Gastric Cancer: A Systematic Review and Meta-analysis of Cohort Studies
Conclusions: This systematic review and meta-analysis indicates that eradication therapy for H. pylori prevents gastric cancer. There was insufficient literature for meta-analysis of MALT lymphoma or esophageal cancer. (Source: JNCI)
Source: JNCI - July 13, 2016 Category: Cancer & Oncology Authors: Doorakkers, E., Lagergren, J., Engstrand, L., Brusselaers, N. Tags: Review Source Type: research

Repeat Prostate-Specific Antigen Tests Before Prostate Biopsy Decisions
Despite limited scientific support, a repeat prostate-specific antigen (PSA) test before prostate biopsy decisions is common. We analyzed biopsy outcomes in 1686 men from the STHLM3 study with PSA 3-10 ng/mL and two PSA tests taken within eight weeks and before prostate biopsy using percentages and multinomial logistic regression. We found that omitting prostate biopsy for men with PSA values decreasing to PSAs of 3 ng/mL or less would save 16.8% of biopsy procedures, while missing 5.4% of the cancers with Gleason scores (GSs) of 7 or higher. The proportion of cancers with GSs of 6 or lower was independent of the first PSA...
Source: JNCI - July 13, 2016 Category: Cancer & Oncology Authors: Nordström, T., Adolfsson, J., Grönberg, H., Eklund, M. Tags: Brief Communication Source Type: research

Family History and Probability of Prostate Cancer, Differentiated by Risk Category: A Nationwide Population-Based Study
Conclusions: The age-specific probabilities of non-low- and high-risk cancer presented here are more informative than relative risks of any prostate cancer and more suitable to use for counseling men with a family history of prostate cancer. (Source: JNCI)
Source: JNCI - July 9, 2016 Category: Cancer & Oncology Authors: Bratt, O., Drevin, L., Akre, O., Garmo, H., Stattin, P. Tags: Article Source Type: research

Comparison of EndoPredict and EPclin With Oncotype DX Recurrence Score for Prediction of Risk of Distant Recurrence After Endocrine Therapy
Conclusions: EP and EPclin were highly prognostic for DR in endocrine-treated patients with ER+, HER2-negative disease. EPclin provided more prognostic information than RS. This was partly but not entirely because of EPclin integrating molecular data with nodal status and tumor size. (Source: JNCI)
Source: JNCI - July 9, 2016 Category: Cancer & Oncology Authors: Buus, R., Sestak, I., Kronenwett, R., Denkert, C., Dubsky, P., Krappmann, K., Scheer, M., Petry, C., Cuzick, J., Dowsett, M. Tags: Article Source Type: research

Response
(Source: JNCI)
Source: JNCI - July 6, 2016 Category: Cancer & Oncology Authors: Lunghi, A., Antonuzzo, L., Laffi, A., Giommoni, E., Di Costanzo, F. Tags: Response Source Type: research

RE: Regorafenib Also Can Cause Osteonecrosis of the Jaw
(Source: JNCI)
Source: JNCI - July 6, 2016 Category: Cancer & Oncology Authors: Fusco, V., Campisi, G., Numico, G., Migliorati, C. A., Santini, D., Bedogni, A. Tags: Correspondence Source Type: research

Distribution and Patterns of Industry-Related Payments to Oncologists in 2014
Conclusions: In 2014, industry-oncologist financial relationships were common, and their impact on oncology practice should be further explored. (Source: JNCI)
Source: JNCI - July 6, 2016 Category: Cancer & Oncology Authors: Marshall, D. C., Moy, B., Jackson, M. E., Mackey, T. K., Hattangadi-Gluth, J. A. Tags: Article Source Type: research