Germline CDKN2A Mutation Status and Survival in Familial Melanoma Cases
Conclusions: CDKN2Amut cases had statistically significantly worse survival than nonmelanoma cancers and, intriguingly, also from melanoma, compared with melanoma cases with no CDKN2A mutations. Further studies are required to elucidate possible mechanisms behind increased carcinogen susceptibility and the more aggressive melanoma phenotype in CDKN2A mutation carriers.
Source: JNCI - Category: Cancer & Oncology Authors: Helgadottir, H., Höiom, V., Tuominen, R., Nielsen, K., Jönsson, G., Olsson, H., Hansson, J. Tags: Article Source Type: research
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