HPV16 Sublineage Associations With Histology-Specific Cancer Risk Using HPV Whole-Genome Sequences in 3200 Women

Conclusions: Specific HPV16 variant sublineages strongly influence risk of histologic types of precancer and cancer, and viral genetic variation may help explain its unique carcinogenic properties.

Source: JNCI - April 28, 2016 Category: Cancer & Oncology Authors: Mirabello, L., Yeager, M., Cullen, M., Boland, J. F., Chen, Z., Wentzensen, N., Zhang, X., Yu, K., Yang, Q., Mitchell, J., Roberson, D., Bass, S., Xiao, Y., Burdett, L., Raine-Bennett, T., Lorey, T., Castle, P. E., Burk, R. D., Schiffman, M. Tags: Article Source Type: research