Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Conclusions: Findings from this large prospective study support a role of oophorectomy for the prevention of premenopausal breast cancer in BRCA2, but not BRCA1 mutation carriers. These findings warrant further evaluation.

Source: JNCI - September 5, 2016 Category: Cancer & Oncology Authors: Kotsopoulos, J., Huzarski, T., Gronwald, J., Singer, C. F., Moller, P., Lynch, H. T., Armel, S., Karlan, B., Foulkes, W. D., Neuhausen, S. L., Senter, L., Tung, N., Weitzel, J. N., Eisen, A., Metcalfe, K., Eng, C., Pal, T., Evans, G., Sun, P., Lubinski, J Tags: Article Source Type: research