GSEA of mouse and human mitochondriomes reveals fatty acid oxidation in astrocytes
Glia, EarlyView. (Source: Glia)
Source: Glia - March 25, 2018 Category: Neurology Source Type: research
Postnatal maturation of microglia is associated with alternative activation and activated TGF β signaling
Glia, EarlyView. (Source: Glia)
Source: Glia - March 25, 2018 Category: Neurology Source Type: research
Influence of white matter injury on gray matter reactive gliosis upon stab wound in the adult murine cerebral cortex
Glia, EarlyView. (Source: Glia)
Source: Glia - March 24, 2018 Category: Neurology Source Type: research
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Glia, Ahead of Print. (Source: Glia)
Source: Glia - March 24, 2018 Category: Neurology Source Type: research
CXCL12 ‐mediated feedback from granule neurons regulates generation and positioning of new neurons in the dentate gyrus
We report that granule neurons (GN) upregulate CXCL12 and CXCR7 during dentate gyrus maturation in the second postnatal week. To test whether GN‐derived CXCL12 regulates neurogenesis and if neuronal CXCR7 receptors influence this process, we conditionally deleted Cxcl12 and Cxcr7 from the granule cell layer. Cxcl12 deletion resulted in lower numbers, increased dispersion and abnormal dendritic growth of immature GN and reduced neurogenesis. Cxcr7 ablation caused an increase in progenitor proliferation and progenitor numbers and reduced dispersion of immature GN. Thus, we provide a new mechanism where CXCL12‐signals fro...
Source: Glia - March 14, 2018 Category: Neurology Authors: Philipp Abe, Hannah M. W üst, Sebastian J. Arnold, Serge A. van de Pavert, Ralf Stumm Tags: RESEARCH ARTICLE Source Type: research
CXCL12 ‐mediated feedback from granule neurons regulates generation and positioning of new neurons in the dentate gyrus
Glia, EarlyView. (Source: Glia)
Source: Glia - March 14, 2018 Category: Neurology Source Type: research
Issue Information ‐ Table of Contents
Glia,Volume 66, Issue 5, Page 903-906, May 2018. (Source: Glia)
Source: Glia - March 14, 2018 Category: Neurology Source Type: research
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Glia, Ahead of Print. (Source: Glia)
Source: Glia - March 14, 2018 Category: Neurology Source Type: research
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Glia,Volume 66, Issue 5, Page 903-906, May 2018. (Source: Glia)
Source: Glia - March 14, 2018 Category: Neurology Source Type: research
Issue Information ‐ Table of Contents
(Source: Glia)
Source: Glia - March 14, 2018 Category: Neurology Tags: ISSUE INFORMATION ‐ TABLE OF CONTENTS Source Type: research
In vivo imaging of Α7 nicotinic receptors as a novel method to monitor neuroinflammation after cerebral ischemia
Abstract
In vivo positron emission tomography (PET) imaging of nicotinic acetylcholine receptors (nAChRs) is a promising tool for the imaging evaluation of neurologic and neurodegenerative diseases. However, the role of α7 nAChRs after brain diseases such as cerebral ischemia and its involvement in inflammatory reaction is still largely unknown. In vivo and ex vivo evaluation of α7 nAChRs expression after transient middle cerebral artery occlusion (MCAO) was carried out using PET imaging with [11C]NS14492 and immunohistochemistry (IHC). Pharmacological activation of α7 receptors was evaluated with magnetic resonance ima...
Source: Glia - March 12, 2018 Category: Neurology Authors: Lorena Col ás, Maria Domercq, Pedro Ramos‐Cabrer, Ana Palma, Vanessa Gómez‐Vallejo, Daniel Padro, Sandra Plaza‐García, Krishna R. Pulagam, Makoto Higuchi, Carlos Matute, Jordi Llop, Abraham Martín Tags: RESEARCH ARTICLE Source Type: research
In vivo imaging of Α7 nicotinic receptors as a novel method to monitor neuroinflammation after cerebral ischemia
Glia, EarlyView. (Source: Glia)
Source: Glia - March 12, 2018 Category: Neurology Source Type: research
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Glia, Ahead of Print. (Source: Glia)
Source: Glia - March 12, 2018 Category: Neurology Source Type: research
Draper ‐mediated JNK signaling is required for glial phagocytosis of apoptotic neurons during Drosophila metamorphosis
This study thus reveals that SIMU unexpectedly is not involved in glial phagocytosis of apoptotic neurons during metamorphosis and highlights the novel role of dJNK signaling in developmental apoptotic cell clearance downstream of Draper.
Main Points
A novel role of JNK signaling in glial phagocytosis during CNS development.
Draper, but not SIMU, is required for glial phagocytosis of apoptotic neurons during metamorphosis.
Draper induces dJNK signaling and an additional pathway in pupal glia. (Source: Glia)
Source: Glia - March 9, 2018 Category: Neurology Authors: Reut Hilu ‐Dadia, Ketty Hakim‐Mishnaevski, Flonia Levy‐Adam, Estee Kurant Tags: RESEARCH ARTICLE Source Type: research
Draper ‐mediated JNK signaling is required for glial phagocytosis of apoptotic neurons during Drosophila metamorphosis
Glia, EarlyView. (Source: Glia)
Source: Glia - March 9, 2018 Category: Neurology Source Type: research
