ECNP Calendar of Events
(Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - February 1, 2018 Category: Psychiatry & Psychology Source Type: research
Contents
(Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - February 1, 2018 Category: Psychiatry & Psychology Source Type: research
From neuroscience to evidence based psychological treatments – The promise and the challenge, ECNP March 2016, Nice, France
This ECNP meeting was designed to build bridges between different constituencies of mental illness treatment researchers from a range of backgrounds with a specific focus on enhancing the development of novel, evidence based, psychological treatments. In particular we wished to explore the potential for basic neuroscience to support the development of more effective psychological treatments, just as this approach is starting to illuminate the actions of drugs. To fulfil this aim, a selection of clinical psychologists, psychiatrists and neuroscientists were invited to sit at the same table. (Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - January 19, 2018 Category: Psychiatry & Psychology Authors: Guy M. Goodwin, Emily A. Holmes, Erik Andersson, Michael Browning, Andrew Jones, Johanna Lass-Hennemann, Kristoffer NT M ånsson, Carolin Moessnang, Elske Salemink, Alvaro Sanchez, Linda van Zutphen, Renée M. Visser Source Type: research
Selective attention to smoking cues in former smokers
Repeated drug use modifies the emotional and cognitive processing of drug-associated cues. These changes are supposed to persist even after prolonged abstinence. Several studies demonstrated that smoking cues selectively attract the attention of smokers, but empirical evidence for such an attentional bias among successful quitters is inconclusive. Here, we investigated whether attentional biases persist after smoking cessation. Thirty-eight former smokers, 34 current smokers, and 29 non-smokers participated in a single experimental session. (Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - January 19, 2018 Category: Psychiatry & Psychology Authors: Anne K. Rehme, Katharina Bey, Ingo Frommann, Karin Mogg, Brendan P. Bradley, Julia Bludau, Verena Block, Birgitta Str äter, Christian G. Schütz, Michael Wagner Source Type: research
The effect of 5-HTTLPR and a serotonergic multi-marker score on amygdala, prefrontal and anterior cingulate cortex reactivity and habituation in a large, healthy fMRI cohort
Major depressive disorder (MDD) is characterized by low mood for at least two weeks. Impaired emotion regulation has been suggested to be the consequence of dysfunctional serotonergic regulation of limbic and prefrontal regions, especially the amygdala, the anterior cingulate cortex (ACC) and the prefrontal cortex (PFC). The impact of genetic variation on brain function can be investigated with intermediate phenotypes. A suggested intermediate phenotype of MDD is emotion recognition: The 5-HTTLPR polymorphism of SLC6A4 as well as other serotonergic genes have been associated with amygdala and prefrontal function during emo...
Source: European Neuropsychopharmacology - January 19, 2018 Category: Psychiatry & Psychology Authors: J.H. Piel, T.A. Lett, C. Wackerhagen, M.M. Plichta, S. Mohnke, O. Grimm, N. Romanczuk-Seiferth, F. Degenhardt, H. Tost, S. Witt, M. N öthen, M. Rietschel, A. Heinz, A. Meyer-Lindenberg, H. Walter, S. Erk Source Type: research
Gray and white matter changes and their relation to illness trajectory in first episode psychosis
Previous works have studied structural brain characteristics in first-episode psychosis (FEP), but few have focused on the relation between brain differences and illness trajectories. The aim of this study is to analyze gray and white matter changes in FEP patients and their relation with one-year clinical outcomes. A sample of 41 FEP patients and 41 healthy controls (HC), matched by age and educational level was scanned with a 3T MRI during the first month of illness onset. One year later, patients were assigned to two illness trajectories (schizophrenia and non-schizophrenia). (Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - January 12, 2018 Category: Psychiatry & Psychology Authors: Alejandro Keymer-Gausset, Anna Alonso-Sol ís, Iluminada Corripio, Rosa B. Sauras-Quetcuti, Edith Pomarol-Clotet, Erick J. Canales-Rodriguez, Eva Grasa-Bello, Enric Álvarez, Maria J. Portella Source Type: research
Epigenetic regulation of the kappa opioid receptor gene by an insertion –deletion in the promoter region
Preclinical and clinical studies have demonstrated that the kappa opioid receptor (KOR) regulates reward, hedonic tone and emotions. At therapeutic level, on-going clinical trials are assessing the potential of targeting the KOR for the management of depression, anxiety disorders and substance use disorders. However, genetic polymorphisms in the KOR gene that potentially contribute to its implication in these phenotypes have been poorly studied. Here we investigated an insertion –deletion in the promoter region of KOR (rs35566036), recently associated with alcohol addiction, in a cohort of depressed subjects who died by ...
Source: European Neuropsychopharmacology - January 11, 2018 Category: Psychiatry & Psychology Authors: Pierre-Eric Lutz, Daniel Almeida, Raoul Belzeaux, Ipek Yalcin, Gustavo Turecki Tags: Short Communication Source Type: research
Cortical folding abnormalities in patients with schizophrenia who have persistent auditory verbal hallucinations
In schizophrenia temporal cortical volume loss differs between patients presenting with persistent auditory verbal hallucinations (pAVH) in contrast to those without hallucinatory symptoms (nAVH). However, it is unknown whether this deficit reflects a neural signature of neurodevelopmental origin or if abnormal temporal cortical volume is reflective of factors which may be relevant at later stages of the disorder. Here, we tested the hypothesis that local gyrification index (LGI) in regions of the temporal cortex differs between patients with pAVH (n=10) and healthy controls (n=14), and that abnormal temporal LGI discrimin...
Source: European Neuropsychopharmacology - January 2, 2018 Category: Psychiatry & Psychology Authors: Katharina M. Kubera, Philipp A. Thomann, Dusan Hirjak, Anja Barth, Fabio Sambataro, Nenad Vasic, Nadine D. Wolf, Karel Frasch, R. Christian Wolf Source Type: research
Factors associated with direct health care costs in schizophrenia: Results from the FACE-SZ French dataset
There is a lack of data on health care consumption of patients suffering from schizophrenia, as well as on the related health care costs. Factors associated with health care costs have not been widely studied, whereas knowledge on this topic would allow identifying risk factors and delineating strategies to improve patients ’ health and follow-up, likely to also decrease health care costs. The aim of this study was to estimate the average direct health care cost of patients with schizophrenia in France and to identify the factors associated with this cost. (Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - January 1, 2018 Category: Psychiatry & Psychology Authors: Charles Laidi, Am élie Prigent, Alice Plas, Marion Leboyer, Guillaume Fond, Karine Chevreul, FACE-SCZ Group Source Type: research
Editorial Board
(Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - January 1, 2018 Category: Psychiatry & Psychology Source Type: research
ECNP Calendar of Events
(Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - January 1, 2018 Category: Psychiatry & Psychology Source Type: research
Contents
(Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - January 1, 2018 Category: Psychiatry & Psychology Source Type: research
Contents Continued
(Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - January 1, 2018 Category: Psychiatry & Psychology Source Type: research
Serotonin transporter gene expression predicts the worsening of suicidal ideation and suicide attempts along a long-term follow-up of a Major Depressive Episode
The quest for biomarkers in suicidal behaviors has been elusive so far, despite their potential utility in clinical practice. One of the most robust biological findings in suicidal behaviors is the alteration of the serotonin transporter function in suicidal individuals. Our main objective was to investigate the predictive value of the serotonin transporter gene expression (SLC6A4) for suicidal ideation and as secondary, for suicide attempts in individuals with a major depressive episode (MDE). A 30-week prospective study was conducted on 148 patients with a MDE and 100 healthy controls including 4 evaluation times (0, 2, ...
Source: European Neuropsychopharmacology - December 27, 2017 Category: Psychiatry & Psychology Authors: Julia-Lou Consoloni, El Ch érif Ibrahim, Marie-Noëlle Lefebvre, Xavier Zendjidjian, Emilie Olié, Pascale Mazzola-Pomietto, Thomas Desmidt, Ludovic Samalin, Pierre-Michel Llorca, Mocrane Abbar, Jorge Lopez-Castroman, Emmanuel Haffen, Karine Baumstarck, Source Type: research
Transdiagnostic deviant facial recognition for implicit negative emotion in autism and schizophrenia
Impaired facial affect recognition (FAR) is observed in schizophrenia and autism spectrum disorder (ASD) and has been linked to amygdala and fusiform gyrus dysfunction. ASD patient's impairments seem to be more pronounced during implicit rather than explicit FAR, whereas for schizophrenia data are inconsistent. However, there are no studies comparing both patient groups in an identical design. The aim of this three-group study was to identify (i) whether FAR alterations are equally present in both groups, (ii) whether they are present rather during implicit or explicit FAR, (iii) and whether they are conveyed by similar or...
Source: European Neuropsychopharmacology - December 21, 2017 Category: Psychiatry & Psychology Authors: Angela Ciaramidaro, Sven B ölte, Sabine Schlitt, Daniela Hainz, Fritz Poustka, Bernhard Weber, Christine Freitag, Henrik Walter Source Type: research
