Editorial Board
(Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - June 20, 2017 Category: Psychiatry & Psychology Source Type: research
ECNP Calendar of Events
(Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - June 20, 2017 Category: Psychiatry & Psychology Source Type: research
Contents
(Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - June 20, 2017 Category: Psychiatry & Psychology Source Type: research
Postpartum estrogen withdrawal impairs GABAergic inhibition and LTD induction in basolateral amygdala complex via down-regulation of GPR30
In this study, ovariectomized (OVX) mice were treated with co-administration of estradiol benzoate and progesterone (E2/P4) followed by administration of E2 alone (E2) and a subsequent E2 withdrawal (EW) to mimic the hormonal changes during pregnancy and postpartum. The objective of this study was to investigate the influence of E2 withdrawal after hormone-simulated pregnancy on synaptic function and plasticity in basolateral amygdala complex (BLA). (Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - June 13, 2017 Category: Psychiatry & Psychology Authors: Rong Yang, Baofeng Zhang, Tingting Chen, Suyun Zhang, Ling Chen Source Type: research
Alpha1-adrenergic receptor blockade in the VTA modulates fear memories and stress responses
Activity of the ventral tegmental area (VTA) and its terminals has been implicated in the Pavlovian associative learning of both stressful and rewarding stimuli. However, the role of the VTA noradrenergic signaling in fear responses remains unclear. We aimed to examine how alpha1-adrenergic receptor ( α1-AR) signaling in the VTA affects conditioned fear. The role of α1-AR was assessed using the micro-infusions into the VTA of the selective antagonists (0.1–1µg/0.5µl prazosin and 1µg/0.5µl terazosin) in acquisition and expression of fear memory. (Source: European Neuropsychopharmacology)
Source: European Neuropsychopharmacology - June 13, 2017 Category: Psychiatry & Psychology Authors: Wojciech B. Solecki, Klaudia Szklarczyk, Kamil Pradel, Grzegorz Dobrza ński, Ryszard Przewłocki Source Type: research
