Clinical Cases in Mineral and Bone Metabolism This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Danio rerio: the Janus of the bone from embryo to scale.
Authors: Mariotti M, Carnovali M, Banfi G Abstract Danio rerio (zebrafish), like the Roman god Janus, is an old animal model which is recently emerged and looks to the future with an increasing scientific success. Unlike other traditional animal models, zebrafish represents a versatile way to approach the study of the skeleton. Transparency of the larval stage, genetic manipulability and unique anatomical structures (scales) makes zebrafish a powerful and versatile instrument to investigate the bone tissue in terms of structure and function. Like Janus, zebrafish offers two different faces, or better, two ...
Source: Clinical Cases in Mineral and Bone Metabolism - December 2, 2015 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research

Periodontal disease in Paget's disease of bone.
Authors: Nuti N, Ferrari M Abstract A 59-year-old man suffering from Paget's disease of bone and periodontal disease was examined in anticipation of bisphosphonate treatment. The previous therapy with clodronate resulted ineffective and markers of bone turnover were markedly elevated. Periodontal disease was correctly approached and treated with an excellent outcome. 5 mg zoledronate iv infusion induced a remarkable reduction of bone markers which persisted on time within the normal range. After zoledronate treatment no signs of osteonecrosis of the jaw (ONJ) were observed. A correct management of periodon...
Source: Clinical Cases in Mineral and Bone Metabolism - December 2, 2015 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research

Primary hyperparathyroidism presenting with acute pancreatitis and asymptomatic bone involvement.
Authors: Saif A Abstract A 15-year-old female patient presented to the emergency room with vomiting and abdominal pain. She had two similar attacks in the previous three months both of them were diagnosed as pancreatitis in two different hospitals. On admission, her serum calcium and parathyroid hormone levels were very high. CT scan revealed left inferior parathyroid adenoma. Investigations to rule out possible multiple endocrine neoplasia were all negative. The patient was managed by intravenous fluids and furosemide to lower her serum calcium level. Then, left inferior parathyroidectomy was done. Postop...
Source: Clinical Cases in Mineral and Bone Metabolism - December 2, 2015 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research

Bulbous epiphysis and popcorn calcification as related to growth plate differentiation in osteogenesis imperfecta.
CONCLUSION: The mutation identified here had been previously described twice in OI patients and no previous correlation with bulbous epiphyseal deformity was described. The occurrence of this bone dysplasia focuses attention on alterations in normal growth plate differentiation and the subsequent effect on endochondral bone formation in OI. PMID: 26604951 [PubMed - as supplied by publisher] (Source: Clinical Cases in Mineral and Bone Metabolism)
Source: Clinical Cases in Mineral and Bone Metabolism - December 2, 2015 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research