Clinical Cases in Mineral and Bone Metabolism 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Bone health in menopausal women: a role for General Practitioners.
Authors: Michieli R, Musto M
Abstract
General Practitioners (GPs) are in a prime location to assess patient health needs, knowing clinical history, living habits and risk factors. GPs can identify in healthy people those in which prevention could be useful, in order to avoid or delay some diseases. For this purpose GPs need to change their care model from a waiting model to a proactive model, in order to identify health needs before the development of diseases.
PMID: 28740528 [PubMed] (Source: Clinical Cases in Mineral and Bone Metabolism)
Source: Clinical Cases in Mineral and Bone Metabolism - July 27, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
Legg-Calv é-Perthes disease: classifications and prognostic factors.
CONCLUSION: Clinical factors of poor prognosis are overweight, female sex, age exceeding 6 years old, and lack of hip abduction. Radiologically, Herring's classification is consensual because of its high prognostic value and very good reproducibility. The other signs of femoral head "at-risk" and the assessment of the reduction in abduction of the femoral head in the acetabulum are also prognostic of late evolution. MRI seems to be a future tool in assessing the fate of hips in LCPD. It is likely that a better understanding of LCPD etiology would precise the prognosis of this disease.
PMID: 28740529 [PubMed] (Sourc...
Source: Clinical Cases in Mineral and Bone Metabolism - July 27, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
Transient osteoporosis of the hip with a contralateral delayed involvement: a case report.
We describe a case of non-simultaneous bilateral hip pain with bone marrow edema occurring in an adult male, with the contralateral hip being involved 12 years later after the onset of symptoms. On the basis of clinical and imaging findings, together with a complete resolution after conservative management, a post-hoc diagnosis of metachronous bilateral transient osteoporosis of the hip (TOH) was made. Non-simultaneous bilateral presentation of TOH is exceptional, and contralateral involvement with a 12-year delay has never been previously described.
PMID: 28740530 [PubMed] (Source: Clinical Cases in Mineral and Bone Metabolism)
Source: Clinical Cases in Mineral and Bone Metabolism - July 27, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
A case report: hypercalcemia due to vitamin supplementation in a patient with neurofibromatosis.
Authors: Crone M, Fogarty K
Abstract
A 54-year-old female with history of neurofibromatosis who presented with severe hypercalcemia and renal failure secondary to over supplementation of calcium and vitamin D.
PMID: 28740531 [PubMed] (Source: Clinical Cases in Mineral and Bone Metabolism)
Source: Clinical Cases in Mineral and Bone Metabolism - July 27, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
Is this a seizure?
We describe a case of a 65-year-old woman admitted to the hospital for suspected of epileptic crisis. She was affected by diabetes and hiatal hernia for which she was taking Proton Pump Inhibitors (PPIs) for about 8 years. She showed hypocalcaemia, hypomagnesaemia, hyperparathyroidism and severe hypovitaminosis D. We exclude malabsorption and magnesium loss. After restored vitamin D levels, stopped use of PPI, start calcium and magnesium supplementation normal values of the ions were restored. This case underlies the importance of evaluate magnesium routinely, other than calcium and vitamin D, and use PPI more carefully.
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Source: Clinical Cases in Mineral and Bone Metabolism - July 27, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
Histological and micro Computed Tomography analysis of a femoral stress fracture associated with prolonged bisphosphonate use.
CONCLUSION: Increased porosity of the cortex and accumulation of microdamage might have lead to a stress fracture and ultimately a complete AFF.
PMID: 28740533 [PubMed] (Source: Clinical Cases in Mineral and Bone Metabolism)
Source: Clinical Cases in Mineral and Bone Metabolism - July 27, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
Primary hyperparathyroidism associated to thrombocytopenia: an issue to consider?
Authors: De Keukeleire S, Muylle K, Tsoumalis G, Vermeulen S, Vogelaers D
Abstract
Primary hyperparathyroidism (PHPT) is probably the most common endocrine disorder of the parathyroid glands, causing hypercalcemia. It is diagnosed often in persons with elevated serum calcium levels. However, hematological manifestations, such as thrombocytopenia are less known. In this case we describe the possible association of PHPT with reversible thrombocytopenia after parathyroidectomy. This hematological abnormality can be included in the spectrum of possible causes, including seemingly non-specific symptoms, in the ...
Source: Clinical Cases in Mineral and Bone Metabolism - July 27, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
Acute severe diarrhoea and hyponatremia after zoledronic acid infusion: an acute phase reaction.
We describe a case of acute watery diarrhoea complicated by severe hyponatremia and hypotension following ZA infusion. The patient needed intensive care for four days. To the best of our knowledge, this type of acute diarrhoea complicated by severe hyponatremia, following ZA infusion, is not reported so far. Strong temporal relation with ZA administration makes it the most likely cause. Furthermore, all laboratory and imaging parameters indicate that the secretory diarrhoea may be a component of acute phase reaction. According to World Health Organization (WHO) causality scale, ZA was a probable cause of acute watery diarr...
Source: Clinical Cases in Mineral and Bone Metabolism - July 27, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
LoCa LoPa myelopathy: is prevention better than cure?
We present a patient of primary hypoparathyroidism who had extensive calcification of brain parenchyma, and was suffering from chronic, generalised and progressive stiffness of body due to cervical compressive myelopathy, caused by calcification of posterior longitudinal ligament and ligamentum flavum. By presenting this case we wanted to emphasize the usefulness of meticulous clinical examination to differentiate the stiffness caused by myelopathy from that which is caused by possible coexisting extrapyramidal disorder. This case presentation also builds the hypothesis that early diagnosis and institution of early and app...
Source: Clinical Cases in Mineral and Bone Metabolism - July 27, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
From the Editor-in-Chief.
Authors: Brandi ML
PMID: 28228776 [PubMed - in process] (Source: Clinical Cases in Mineral and Bone Metabolism)
Source: Clinical Cases in Mineral and Bone Metabolism - February 24, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
Natural mineral waters: chemical characteristics and health effects.
Authors: Quattrini S, Pampaloni B, Brandi ML
Abstract
Water contributes significantly to health and a daily intake of 1.5 to 2 liters of water should be guaranteed, because a good hydration is essential to maintain the body water equilibrium, although needs may vary among people. However, worldwide population is far from the Recommended Allowance for water intake. Among the waters for human uses, there are 'waters (treated or not), intended for drinking, used for the food and beverages preparation or for other domestic purposes' and natural mineral waters, that are 'originated from an aquifer or undergroun...
Source: Clinical Cases in Mineral and Bone Metabolism - February 24, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
Microelements for bone boost: the last but not the least.
Authors: Pepa GD, Brandi ML
Abstract
Osteoporosis is a major public health problem affects many millions of people around the world. It is a metabolic bone disease characterized by loss of bone mass and strength, resulting in increased risk of fractures. Several lifestyle factors are considered to be important determinants of it and nutrition can potentially have a positive impact on bone health, in the development and maintenance of bone mass and in the prevention of osteoporosis. There are potentially numerous nutrients and dietary components that can influence bone health, and these range from the macro...
Source: Clinical Cases in Mineral and Bone Metabolism - February 24, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
A retrospective study on screening and management of osteoporosis in breast cancer women treated with aromatase inhibitors in Libya.
This study aimed to improve the medical assistance given to patients under AI treatment to minimize secondary osteoporosis. Fifty Libyan postmenopausal women treated with AI to fight breast cancer were selected from attendants Tripoli Medical Center (TMC), Oncology Department during year 2014. A closed questionnaire was requested from each women including data about age, age at AI therapy, and types of AI, age at bone densitometry measurement, onset and symptoms of osteoporosis, treatment of osteoporosis and measurement of vitamin D and calcium supplement given. The study revealed a poor consideration given to apply the re...
Source: Clinical Cases in Mineral and Bone Metabolism - February 24, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
The relationship between vitamin D receptor (VDR) polymorphism and the occurrence of osteoporosis in menopausal Iranian women.
CONCLUSION: The relationship between the genotypes and osteoporosis, cancers, and mineral metabolism disorders has been studied for a long time. Although there has been a significant relation between the aforementioned genotypes and osteoporosis or reduced mineral density-related bone fractures in some studied, some other studies have opposing results. Therefore, it is only possible to reach an acceptable conclusion by studying the haplotype of the polymorphisms in subjects.
PMID: 28228780 [PubMed - in process] (Source: Clinical Cases in Mineral and Bone Metabolism)
Source: Clinical Cases in Mineral and Bone Metabolism - February 24, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
Denosumab is really effective in the treatment of osteoporosis secondary to hypogonadism in prostate carcinoma patients? A prospective randomized multicenter international study.
CONCLUSION: In our study denosumab and alendronate showed similar clinical efficacy in the therapy of ADT-related osteoporosis in men with prostate carcinoma; both drugs provided significant improvements in back pain and general health conditions. Denosumab showed significant increase of BTMs and BMD than alendronate with lower rate of new vertebral fractures.
PMID: 28228781 [PubMed - in process] (Source: Clinical Cases in Mineral and Bone Metabolism)
Source: Clinical Cases in Mineral and Bone Metabolism - February 24, 2017 Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research
