Bulbous epiphysis and popcorn calcification as related to growth plate differentiation in osteogenesis imperfecta.

CONCLUSION: The mutation identified here had been previously described twice in OI patients and no previous correlation with bulbous epiphyseal deformity was described. The occurrence of this bone dysplasia focuses attention on alterations in normal growth plate differentiation and the subsequent effect on endochondral bone formation in OI. PMID: 26604951 [PubMed - as supplied by publisher]
Source: Clinical Cases in Mineral and Bone Metabolism - Category: Orthopaedics Tags: Clin Cases Miner Bone Metab Source Type: research