Limfohistiocytoza hemofagocytarna u dzieci
Publication date: Available online 13 October 2016 Source:Acta Haematologica Polonica Author(s): Magdalena Wołowiec, Iwona Malinowska Hemophagocytic lymphohistiocytosis (HLH) is a heterogenic syndrome characterized by an acute, life-threatening inflammation due to a highly stimulated but ineffective immune response. Depending on the etiology, HLH is divided into primary (genetic) and secondary (acquired) forms. Primary HLH can be divided into familial HLH and HLH associated with other genetic disorders. Secondary HLH usually occurs in the context of a severe infection, rheumatic disease, or malignancy. HLH in children...
Source: Acta Haematologica Polonica - October 14, 2016 Category: Hematology Source Type: research
Association of rs1319868, rs1567811 and rs8041224 of IGF1R gene with infection among sickle cell anemia Tunisian patients
Conclusion These significant associations of IGF1R SNPs with infection suggest that this gene could play an important role in the immune function in SCA. (Source: Acta Haematologica Polonica)
Source: Acta Haematologica Polonica - October 14, 2016 Category: Hematology Source Type: research
Precursor B-lymphoblastic lymphoma mimicking: An acute subdural hematoma
Conclusion Subdural lymphoma can present as a neurosurgical emergency, and lymphoma should be considered as a rare but possible diagnosis before operation. (Source: Acta Haematologica Polonica)
Source: Acta Haematologica Polonica - October 14, 2016 Category: Hematology Source Type: research
Analiza mutacji talasemii alfa u chorych diagnozowanych w Instytucie Hematologii i Transfuzjologii
Conclusions Molecular analysis of the alpha-globin cluster is required for a correct diagnosis in patients with normal or reduced level of HbA2. The results of the study show that due to the progressive migration of the population and globalization, thalassemia must be included in the differential diagnosis of anemia in Poland. (Source: Acta Haematologica Polonica)
Source: Acta Haematologica Polonica - October 14, 2016 Category: Hematology Source Type: research
Retrospektywna analiza skuteczno ści nilotynibu i dazatynibu w drugiej linii terapii przewlekłej białaczki szpikowej w polskich ośrodkach hematologicznych
In conclusion, the results of our analysis indicate that nilotinib and dasatinib have comparable and satisfactory efficacy in the treatment of CML patients refractory or intolerant to imatinib. Our findings support current strategy of choice of IKT-2G according to drug toxicity profile and risk of specific adverse events in an individual patient. (Source: Acta Haematologica Polonica)
Source: Acta Haematologica Polonica - August 17, 2016 Category: Hematology Source Type: research
Monocyty z ekspresj ą Tie-2 u chorych na przewlekłą białaczkę limfocytową
Publication date: Available online 16 August 2016 Source:Acta Haematologica Polonica Author(s): Agnieszka Bojarska-Junak, Piotr Grundszok, Małgorzata Waldowska, Justyna Woś, Sylwia Chocholska, Iwona Hus, Wioleta Kowalska, Katarzyna Gęca, Waldemar Tomczak, Jacek Roliński Introduction In peripheral blood, monocytes form a heterogeneous population of cells. One particular subset of circulating monocytes is expressing the angiopoietin receptor Tie-2 (Tie2-expressing monocyte; TEM). TEM are characterized by tumor promoting properties. However, the role of TEM in chronic lymphocytic leukemia (CLL) immunopathogene...
Source: Acta Haematologica Polonica - August 16, 2016 Category: Hematology Source Type: research
Rekomendacje diagnostyczne i terapeutyczne dla przewlek łej białaczki limfocytowej w 2016 r – Raport Grupy Roboczej PTHiT i PALG-CLL
Publication date: Available online 16 August 2016 Source:Acta Haematologica Polonica Author(s): Tadeusz Robak, Iwona Hus, Krzysztof Giannopoulos, Jerzy Błoński, Krzysztof Jamroziak, Jacek Roliński, Piotr Smolewski, Dariusz Wołowiec The management of patients with chronic lymphocytic leukaemia (CLL) is currently undergoing improvements, particularly because of novel therapies. Purine analogs based immuno-chemotherapy, particularly fludarabine combined with cyclophosphamide and rituximab (FCR), is still the current standard of care for first line therapy in younger, fit patients. However, its use in older, co-m...
Source: Acta Haematologica Polonica - August 16, 2016 Category: Hematology Source Type: research
Stres siateczki śródplazmatycznej i stres oksydacyjny w ostrych białaczkach szpikowych
Publication date: Available online 6 August 2016 Source:Acta Haematologica Polonica Author(s): Justyna Chlebowska Use of differentiation-inducing agents (all-trans retinoic acid and arsenic trioxide) that degradate fusion PML-RARα receptor have revolutionized management of acute promyelocytic (APL) leukemia in 2008. However, despite significant advances in the treatment of APL, the cure rates of patients suffering with other acute myeloid leukemia (AML) subtypes are still not satisfying. Abnormal reactive oxygen species levels and constitutive expression of ER stress marker proteins are characteristic of AML. AML patie...
Source: Acta Haematologica Polonica - August 7, 2016 Category: Hematology Source Type: research
Jak nie b łądzić we mgle – rzecz o współpracy klinika–patomorfologia
Publication date: September 2015 Source:Acta Haematologica Polonica, Volume 46, Supplement 1 Author(s): R. Maryniak, R. Koktysz, J. Patera (Source: Acta Haematologica Polonica)
Source: Acta Haematologica Polonica - July 20, 2016 Category: Hematology Source Type: research
Znaczenie rokownicze rearan żacji genu MECOM (EVI1) u pacjentów z przewlekłą białaczką szpikową
Publication date: September 2015 Source:Acta Haematologica Polonica, Volume 46, Supplement 1 Author(s): A. Stefaniak, A. Kulikowska, A. Pastwińska, E. Chmarzyńska-Mróz, K. Pawelec, M. Matysiak, M. Paluszewska, M. Tormanowska, W.W. Jędrzejczak, B. Ratajczak, M. Jarmuż-Szymczak, M. Lewandowska, L. Gil, M. Komarnicki, K. Borkowska, B. Pieńkowska-Grela, O. Haus, A. Jaśkowiec, S. Stąpor, E. Bodzenta, B. Górnicka (Source: Acta Haematologica Polonica)
Source: Acta Haematologica Polonica - July 20, 2016 Category: Hematology Source Type: research
Wp ływ wielkości klonu z aberracjami w technice FISH na rokowanie u chorych z przewlekłą białaczką limfocytową
Publication date: September 2015 Source:Acta Haematologica Polonica, Volume 46, Supplement 1 Author(s): M. Jakóbczyk, J. Komenda, E. Zdzilowska, K. Kamska, A. Dyrka, S. Czekalska, M. Piotrowska, A.B. Skotnicki (Source: Acta Haematologica Polonica)
Source: Acta Haematologica Polonica - July 20, 2016 Category: Hematology Source Type: research
Udoskonalenie diagnostyki talasemii oraz analiza mutacji wyst ępujących u polskich chorych
Publication date: September 2015 Source:Acta Haematologica Polonica, Volume 46, Supplement 1 Author(s): J. Skulimowska, E. Klimczak-Jajor, P. Turowski, H. Pyl, K. Guz, J. Spychalska, E. Gołaszewska, M. Uhrynowska, E. Mendek-Czajkowska, E. Brojer (Source: Acta Haematologica Polonica)
Source: Acta Haematologica Polonica - July 20, 2016 Category: Hematology Source Type: research
Molekularne monitorowanie leczenia przewlek łej białaczki szpikowej – czynniki prognostyczne i dynamika odpowiedzi
Publication date: September 2015 Source:Acta Haematologica Polonica, Volume 46, Supplement 1 Author(s): M. Gniot, K. Lewandowski, M. Lewandowska, A. Lehmann-Kopydłowska, R. Kroll-Balcerzak, A. Balcerzak, M. Iwoła, M. Komarnicki (Source: Acta Haematologica Polonica)
Source: Acta Haematologica Polonica - July 20, 2016 Category: Hematology Source Type: research
Nowoczesna diagnostyka i monitorowanie ostrych bia łaczek wg standardów EuroFlow
Publication date: September 2015 Source:Acta Haematologica Polonica, Volume 46, Supplement 1 Author(s): T. Szczepański (Source: Acta Haematologica Polonica)
Source: Acta Haematologica Polonica - July 20, 2016 Category: Hematology Source Type: research
Fizjoterapia po zabiegu endoprotezoplastyki stawu skokowego u pacjenta chorego na hemofili ę – opis przypadku
Conclusions Function of the ankle joint significantly improved, the level of pain decreased and time needed to complete the TUG test shortened. The range of motion as well as strength of the muscles acting on the ankle joint improved slightly. (Source: Acta Haematologica Polonica)
Source: Acta Haematologica Polonica - July 20, 2016 Category: Hematology Source Type: research
