Congenital aortic valve repair using CorMatrix ®: A histologic evaluation
ConclusionsOur results suggest a mixed immunological response of remodeling and inflammation following the implantation. The expected process of seeding/migration and remodeling of the bioscaffold into the typical 3‐layered architecture were not observed in our explanted specimens. (Source: Xenotransplantation)
Source: Xenotransplantation - September 22, 2017 Category: Transplant Surgery Authors: Michael Hofmann, Martin O. Schmiady, Barbara E. Burkhardt, Hitendu H. Dave, Michael H übler, Oliver Kretschmar, Peter K. Bode Tags: BRIEF COMMUNICATION Source Type: research
Xenotransplantation literature update, July/August 2017
(Source: Xenotransplantation)
Source: Xenotransplantation - September 11, 2017 Category: Transplant Surgery Authors: Mohammed Ezelerab, Christopher Burlak Tags: LITERATURE UPDATE Source Type: research
IXA 2017 ‐ Abstracts of the 14th Congress of the International Xenotransplantation Association, Baltimore, USA
(Source: Xenotransplantation)
Source: Xenotransplantation - September 11, 2017 Category: Transplant Surgery Tags: ABSTRACT Source Type: research
David J. G. White, PhD, FRCPath
(Source: Xenotransplantation)
Source: Xenotransplantation - September 11, 2017 Category: Transplant Surgery Authors: Emanuele Cozzi, Richard N. Pierson, John Wallwork, David K.C. Cooper, Peter J. Friend, Agnes Azimzadeh, Leo Buhler, Peter Cowan Tags: IN MEMORIAM Source Type: research
Issue Information
(Source: Xenotransplantation)
Source: Xenotransplantation - September 11, 2017 Category: Transplant Surgery Tags: ISSUE INFORMATION Source Type: research
Cover Image, Volume 24, Issue 5
Abstracts of the 14th congress of the International Xenotransplantation Association, Baltimore, USA, September 20 – 23, 2017, Xenotransplantation. 2017;24:e12328. https://doi.org/10.1111/xen.12328 (Source: Xenotransplantation)
Source: Xenotransplantation - September 11, 2017 Category: Transplant Surgery Tags: COVER IMAGE Source Type: research
Miscellaneous
(Source: Xenotransplantation)
Source: Xenotransplantation - September 1, 2017 Category: Transplant Surgery Authors: David K. C. Cooper, Peter Cowan, Jay A. Fishman, Bernhard J. Hering, Muhammad M. Mohiuddin, Richard N. Pierson, David H. Sachs, Henk ‐Jan Schuurman, John U. Dennis, Ralf R. Tönjes Tags: MISCELLANEOUS Source Type: research
Meeting report: The first international conference on xenotransplantation in Chengdu, China
(Source: Xenotransplantation)
Source: Xenotransplantation - September 1, 2017 Category: Transplant Surgery Authors: Xiang Li, Yi Wang, Shaoping Deng Tags: Miscellaneous Source Type: research
Xenotransplantation literature update, September ‐October 2017
(Source: Xenotransplantation)
Source: Xenotransplantation - September 1, 2017 Category: Transplant Surgery Authors: Eric M. Walters, Christopher Burlak Tags: LITERATURE UPDATE Source Type: research
Enhanced effect of human mesenchymal stem cells expressing human TNF ‐αR‐Fc and HO‐1 gene on porcine islet xenotransplantation in humanized mice
ConclusionsOur results suggest that HO‐1/sTNF‐αR‐MSCs are efficient tools for porcine islet xenotransplantation, and this study may provide basic information for pre‐clinical animal models and future clinical trials of porcine islet xenotransplantation. (Source: Xenotransplantation)
Source: Xenotransplantation - September 1, 2017 Category: Transplant Surgery Authors: Han ‐Sin Lee, Sanghyun Song, Du Yeon Shin, Geun‐Soo Kim, Jong‐Hyun Lee, Chan Woo Cho, Kyo Won Lee, Hyojun Park, Curie Ahn, Jaeseok Yang, Heung‐Mo Yang, Jae Berm Park, Sung‐Joo Kim Tags: ORIGINAL ARTICLE Source Type: research
Inactivation of porcine endogenous retrovirus in pigs using CRISPR ‐Cas9, editorial commentary
(Source: Xenotransplantation)
Source: Xenotransplantation - September 1, 2017 Category: Transplant Surgery Authors: Linda Scobie, Joachim Denner, Henk ‐Jan Schuurman Tags: COMMENTARY Source Type: research
Low anti ‐pig antibody levels are key to the success of solid organ xenotransplantation: But is this sufficient?
(Source: Xenotransplantation)
Source: Xenotransplantation - September 1, 2017 Category: Transplant Surgery Authors: David K. C. Cooper, Mohamed B. Ezzelarab, Hidetaka Hara Tags: COMMENTARY Source Type: research
Different approaches to heart valve decellularization: A comprehensive overview of the past 30 years
This article presents a review of 30 years of decellularization approaches adopted in cardiovascular tissue engineering, with a focus on the use, either individually or in combination, of different detergents. The safety and efficacy of cell‐removal procedures are specifically reported and discussed, as well as the structure and biomechanics of the treated extracellular matrix (ECM). Detergent residues within the ECM, production of hyaluronan fragments, safe removal of cellular debris, and the persistence of the alpha‐Gal epitope after the decellularization treatments are of particular interest as parameters for the i...
Source: Xenotransplantation - September 1, 2017 Category: Transplant Surgery Authors: Filippo Naso, Alessandro Gandaglia Tags: REVIEW ARTICLE Source Type: research
Ex vivo ‐expanded baboon CD39 + regulatory T cells prevent rejection of porcine islet xenografts in NOD‐SCID IL‐2rγ−/− mice reconstituted with baboon peripheral blood mononuclear cells
ConclusionOur data supports the capacity of ex vivo expanded CD39+ baboon Treg to suppress islet xenograft rejection in primatized mice, suggesting it has potential as an adjunctive immunotherapy in preclinical NHP models of xenotransplantation. (Source: Xenotransplantation)
Source: Xenotransplantation - September 1, 2017 Category: Transplant Surgery Authors: Dandan Huang, Ya Wang, Wayne J. Hawthorne, Min Hu, Joanne Hawkes, Heather Burns, Sussan Davies, Feng Gao, Yi Vee Chew, Shounan Yi, Philip J. O'Connell Tags: ORIGINAL ARTICLE Source Type: research
Comprehensive evaluation of decellularized porcine corneal after clinical transplantation
Abstract
Corneal disease is the second most common blinding disease in the world. The shortage of cornea donors has become the greatest challenge in curing corneal disease. Decellularized porcine corneas have the potential to be clinically applied as a substitute for human cornea in lamellar keratoplasty. Porcine corneas will help relieve the cornea donor shortage. To comprehensively evaluate the characteristics of the grafts and the effect of the decellularized porcine cornea on the host cornea after clinical transplantation, we assessed the microstructure of the transplanted decellularized porcine corneal tissues. Throug...
Source: Xenotransplantation - September 1, 2017 Category: Transplant Surgery Authors: Yan Shi, Timur Bikkuzin, Zhen Song, Xin Jin, Hao Jin, Xinlei Li, Hong Zhang Tags: BRIEF COMMUNICATION Source Type: research
