The International Journal of Lower Extremity Wounds This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A Rare Cause of Lower Extremity Ulcers: Prolidase Deficiency
This study describes 4 patients with recurrent leg ulcerations and abnormal facies who were first clinically suspected of prolidase deficiency and then biochemically confirmed. Two siblings and 2 other patients were admitted to our clinic at different times, and they had some common features such as chronic leg and foot ulcers recalcitrant to treatment, consanguineous parents, facial dysmorphism, mental retardation, and widespread telangiectasias. Physical examination and detection of low prolidase level in blood finally led us to the diagnose of ulcers secondary to prolidase deficiency. Prolidase deficiency is a rare geno...
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Adısen, E., Erduran, F. B., Ezgü, F. S., Kasapkara, C. S., Besio, R., Forlino, A., Gürer, M. A. Tags: Case Reports Source Type: research

Novel Use of Synthetic Acellular Dermal Matrix for Coverage of a Tibial Defect Following Resection of an Osteochondroma: A Case Report
The application of an artificial dermal matrix (Integra Life Sciences, Plainsboro, NJ) in the management of substantial burn injuries has been extensively documented. Use of an artificial dermal matrix has resulted in excellent outcomes and is free of the morbidity associated with harvesting free-tissue flaps. However, coverage of bony defects where the periosteum has been removed is often challenging. In the current report, we present a case wherein the use of an acellular synthetic dermis combined with split-thickness skin grafting resulted in successful coverage of a tibial defect following resection of an osteochondrom...
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Shamian, B., Hinds, R. M., Capo, J. T. Tags: Case Reports Source Type: research

Amantadine-Induced Livedo Racemosa
Although livedo reticularis is a known adverse effect of amantadine, only limited studies have addressed this association. Livedo racemosa in contrast to livedo reticularis is characterized by a striking violaceous netlike pattern of the skin similar to livedo reticularis with a different histopathology and morphology (irregular, broken circular segments). In this case report, we present 2 cases of livedo racemosa and edema of lower extremities following amantadine treatment. The cutaneous biopsies in both cases showed intraluminal thrombi in subcutaneous blood vessels without evidence of vasculitis, which is consistent wi...
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Criado, P. R., Alavi, A., Valente, N. Y. S., Sotto, M. N. Tags: Case Reports Source Type: research

Combating Superbug Without Antibiotic on a Postamputation Wound in a Patient With Diabetic Foot
We present a diabetic patient with a postamputation wound infected by multidrug-resistant Acinetobacter baumannii/haemolyticus, which was resistant to almost all antibiotics. As the clinical response to antimicrobial therapy was poor, antibiotic was discontinued. Autologous platelet-rich gel with anticoagulation, negative pressure wound therapy, and improvement of microcirculation were used successfully to eradicate infection of the superbug and achieve final wound closure. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Sun, S., Wang, C., Chen, D., Cen, S., Lv, X., Wen, X., Liu, M., Lu, W., Zhao, J., Ran, X. Tags: Case Reports Source Type: research

Compartment Syndrome After Varicose Vein Surgery Evidenced by CT Images
A 21-year-old man developed compartment syndrome after a varicose vein surgery. Because of a lack of appropriate diagnostic apparatus, it was not possible to measure calf pressure. The only diagnostic tool available was computed tomography (CT). With the aid of CT, faster diagnosis of the compartment syndrome was possible, leading to appropriate management. By providing unique CT images of a patient before and after having compartment syndrome and after a fasciotomy, this study could add valuable references for diagnosis of compartment syndrome using CT. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Wang, S.-M., Kim, M. Tags: Case Reports Source Type: research

Complicated Skin and Skin Structure Infection After Erysipelas: Urgent Need for Antibiosis and Surgery
We report on a 65-year-old woman with leg ulcer who developed an absceding and necrotizing panniculitis of the affected leg complicating erysipelas. Escherichia coli and Pseudomonas aeruginosa were identified. Debridement and surgical removal of inflamed subcutaneous adipose tissue was decisive to interrupt the process. Wound bed preparation was realized by vacuum-assisted closure. Final wound closure was done by split-skin mesh graft. Complicated skin and skin structure infections need a combined approach of intensified antibiosis and surgery to save life. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Wollina, U., Langner, D., Heinig, B., Schönlebe, J., Nowak, A. Tags: Case Reports Source Type: research

Efficacy of a New Heparan Sulfate Mimetic Dressing in the Healing of Foot and Lower Extremity Ulcerations in Type 2 Diabetes: A Case Series
In conclusion, these results, although preliminary, are encouraging and suggest adequate efficacy and safety of the new product in difficult-to-heal foot and lower extremity ulcerations in type 2 diabetes. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Papanas, N., Demetzos, C., Pippa, N., Maltezos, E., Tentolouris, N. Tags: Case Reports Source Type: research

The Point Prevalence of Malignancy in a Wound Clinic
This study was a retrospective investigation of patients with chronic leg ulcers in a North American tertiary wound clinic. Between January 2011 and September 2013, a total of 1189 patients with lower extremity wounds, including 726 patients with leg wounds, were identified. A total of 124 of the 726 had undergone a biopsy of their atypical wound, 16.1% (20/124) of which were malignant. Patients with malignant wounds were older than patients with nonmalignant leg wounds (P < .0001), and the common location of the malignant wound was the anterior shin (odds ratio = 3.5). The limitation of this analysis is the lack of dis...
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Ghasemi, F., Anooshirvani, N., Sibbald, R. G., Alavi, A. Tags: Clinical and Translational Research Source Type: research

Knowledge, Attitude, and Practice in the Management of Mixed Arteriovenous Leg Ulcers
Leg ulceration is a chronic health condition that constitutes a significant disease burden. In this cross-sectional descriptive study, a sample of wound care clinicians were asked to respond to a web-based survey. Based on a review of literature and recommended best practices in the management of mixed arteriovenous (AV) ulcers, a questionnaire was developed to examine the knowledge, attitude, and practice pattern in the management of AV ulcers. A total of 436 clinicians participated in the survey. A number of assessment techniques were perceived to be relevant for the assessment of AV ulcers; medical history and the appea...
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Woo, K. Y., Sears, K. Tags: Clinical and Translational Research Source Type: research

Effectiveness of Platelet-Rich Plasma to Enhance Healing of Diabetic Foot Ulcers in Patients With Concomitant Peripheral Arterial Disease and Critical Limb Ischemia
In conclusion, PRP could serve as a useful adjunct during management of diabetic foot ulcers even in diabetic patients with unreconstructable arterial disease. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Kontopodis, N., Tavlas, E., Papadopoulos, G., Pantidis, D., Kafetzakis, A., Chalkiadakis, G., Ioannou, C. Tags: Clinical and Translational Research Source Type: research

Higher Levels of Serum Triglycerides Were Associated With Postoperative Deep Vein Thrombosis After Total Hip Arthroplasty in Patients With Nontraumatic Osteonecrosis of the Femoral Head
This retrospective study aimed to evaluate the association of serum lipids and deep vein thrombosis (DVT) risk following total hip arthroplasty (THA) in patients with nontraumatic osteonecrosis of the femoral head (ONFH). A total of 224 nontraumatic ONFH patients were enrolled. Serum levels of triglycerides (TG), total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol were detected preoperatively. All the patients underwent unilateral lower extremity venography on postoperative days 3 to 5 for DVT screening. In females, patients who were venogram positive for DVT had a higher serum ...
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Xu, Z., Dai, X., Yao, Y., Shi, D., Chen, D., Dai, J., Teng, H., Jiang, Q. Tags: Clinical and Translational Research Source Type: research

Repairing Pretibial and Foot Soft Tissue Defects With Reverse Transplantation of the Medial Crural Fasciocutaneous Flap
In conclusion, the medial crural fasciocutaneous flap is a safe and effective clinical intervention for the reconstruction of soft tissue defects of the pretibial area and foot. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Wu, J., Wu, J., Gong, X., Ding, Z., Lin, B., Chen, Z., Guo, Z. Tags: Clinical and Translational Research Source Type: research

Prevalence and Correlates of Lower-Extremity Amputation in Patients With Diabetic Foot Ulcer in Jeddah, Saudi Arabia
This cross-sectional study investigated the prevalence and correlates of lower-extremity amputation (LEA) in a Saudi population with diabetic foot ulcer. The study population consisted of 91 participants, with a median age of 55.0 years. Biomarkers were measured following standard protocols. Local symptoms of foot ulcer, including peripheral neuropathy (PN), peripheral artery disease (PAD), and foot infection were diagnosed by standard objective diagnostic tools or diagnosed clinically by a specialized surgeon. The severity of foot ulcer was classified according to the Wagner wound classification system. The prevalence of ...
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Wang, D. D., Jamjoom, R. A., Alzahrani, A. H., Hu, F. B., Alzahrani, H. A. Tags: Clinical and Translational Research Source Type: research

Predictors of Outcomes in Diabetic Foot Osteomyelitis Treated Initially With Conservative (Nonsurgical) Medical Management: A Retrospective Study
The optimal way to manage diabetic foot osteomyelitis remains uncertain, with debate in the literature as to whether it should be managed conservatively (ie, nonsurgically) or surgically. We aimed to identify clinical variables that influence outcomes of nonsurgical management in diabetic foot osteomyelitis. We conducted a retrospective study of consecutive patients with diabetes presenting to a tertiary center between 2007 and 2011 with foot osteomyelitis initially treated with nonsurgical management. Remission was defined as wound healing with no clinical or radiological signs of osteomyelitis at the initial or contiguou...
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Zeun, P., Gooday, C., Nunney, I., Dhatariya, K. Tags: Clinical and Translational Research Source Type: research

Innovation, Translation, and Cooperation
The 9th Wound Healing and Tissue Repair and Regeneration Annual Meeting of Chinese Tissue Repair Society was hold in Wuhan, China. This meeting was focused on the innovation, translation application, and cooperation in wound care both in China and other countries. More than 400 delegates took part in this meeting and communicated successfully. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - March 1, 2016 Category: Surgery Authors: Fu, X. Tags: Seminar Review Source Type: research