Skeletal Tuberculosis Following Proximal Tibia Fracture
Over the past several years, there has been a rise in incidence of tuberculosis in both developing and developed countries. Tuberculosis complicating a fracture is uncommon. In this article, we report the case of a 10-year-old patient with a proximal tibia fracture who developed discharging wound over the fracture site after 2 weeks of initial trauma. The fracture was showing no signs of healing. A diagnosis of tuberculosis of proximal tibia was made on the basis of polymerase chain reaction and histology. After antituberculous treatment was started, the sinus healed and the fracture united. To the best of our knowledge, s...
Source: The International Journal of Lower Extremity Wounds - March 15, 2013 Category: Surgery Authors: Meena, S., Rastogi, D., Barwar, N., Morey, V., Goyal, N. Tags: Case Report Source Type: research

Calcific Myonecrosis of the Leg Treated by Debridement and Limited Access Dressing
We report 2 cases of calcific myonecrosis involving the anterior compartment of the leg that presented to us in an advanced stage of multiple sinuses discharging calcific material. Incision and drainage had been attempted at a local hospital prior to presentation at our hospital resulting in a non healing wound. Both patients had a history of antecedent trauma to the leg a few years ago. Patients were treated by thorough debridement of the involved muscles in the anterior compartment. Limited access dressing (LAD) was used to manage the dead space left after debridement. After application of the LAD, the wound was covered ...
Source: The International Journal of Lower Extremity Wounds - March 15, 2013 Category: Surgery Authors: Sreenivas, T., Nandish Kumar, K. C., Menon, J., Nataraj, A. R. Tags: Case Report Source Type: research

Total Hip Replacement in an Ipsilateral Above-the-Knee Amputation: Surgical Technique, Rehabilitation, and Review of the Literature
In this article, we present a case report of a 62-year-old patient who previously underwent an above-the-knee amputation for vascular disease and we performed a total hip replacement on him because of hip osteoarthritis. As the only postoperative complication, the patient developed a methicillin-resistant Staphylococcus aureus surgical site infection, which was successfully treated. The surgical technique and the postoperative rehabilitation program are described in detail in an attempt to detect and face the challenges that patients with major lower limb amputations may present. The literature is reviewed and all known ca...
Source: The International Journal of Lower Extremity Wounds - March 15, 2013 Category: Surgery Authors: Malagelada, F., Coll Rivas, M., Jimenez Obach, A., Auleda, J., Guirao, L., Pleguezuelos, E. Tags: Case Report Source Type: research

Factor V Leiden Mutation-Related Chronic Skin Ulcers
Chronic skin ulcers require extensive, systemic differential diagnosis; thus, they are difficult to diagnose and treat. Transient or persistent hypercoagulable states are among the rare causes of skin ulcers. Here, we present the case of a 27-year-old woman patient with recurrent, nonhealing skin ulcers of 8 years’ duration, who had been treated unsuccessfully with various medications under different diagnoses at different clinics. On admission, a skin biopsy demonstrated occlusive vasculopathy, and the search for an inherited hypercoagulable state revealed a heterozygous factor V Leiden mutation. The patient was tre...
Source: The International Journal of Lower Extremity Wounds - March 15, 2013 Category: Surgery Authors: Kayatas, K., Cebeci, F., Karatoprak, C., Benzer, M., Demirtunc, R., Demirkesen, C. Tags: Case Report Source Type: research

A Chronic Leg Ulcer Presenting With Charcot-Marie-Tooth Disease and Type 2 Diabetes: A Case Report
This article reports a man who presented with the symptoms mentioned above and also with a leg ulcer and type 2 diabetes. He was diagnosed with CMT disease based on family history and genetic testing. A skin defect in the left leg had manifested for more than 1 year, and results of initial fasting plasma glucose revealed type 2 diabetes. The evolution of these manifestations, coupled with a slowly progressive weakness, numbness, muscular wasting, and sensory impairment, strongly suggested the co-occurrence of 3 different diseases in the same individual. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - March 15, 2013 Category: Surgery Authors: Ren, H., You, C., Han, C. Tags: Case Report Source Type: research

Evaluation of the Effects of Homologous Platelet Gel on Healing Lower Extremity Wounds in Patients With Diabetes
The treatment of chronic diabetic wounds remains complicated, despite new insight into the cellular and molecular basis of wound healing and cutaneous regeneration. A growing body of clinical trials has shown that platelet release has a notable effectiveness on refractory ulcer healing. However, patients with chronic diabetic ulcers usually have poor general health, and the large-volume blood absence required to produce autologous platelet-rich plasma often causes adverse effects. To overcome the limitation, the homologous platelet gel (PG) from healthy donor was used for the treatment of chronic diabetic lower extremity w...
Source: The International Journal of Lower Extremity Wounds - March 15, 2013 Category: Surgery Authors: Shan, G.-Q., Zhang, Y.-N., Ma, J., Li, Y.-H., Zuo, D.-M., Qiu, J.-l., Cheng, B., Chen, Z.-L. Tags: Case Report Source Type: research

Wireless Electrical Stimulation: An Innovative Powerful Tool for the Treatment of a Complicated Chronic Ulcer
We present here the implementation of a new wireless electrical stimulation technique for the treatment of a complicated chronic ulcer of the lower limb. The device is transferring charges to the wound, without any contact with it, creating a microcurrent that is able to generate the current of injury. The results suggest that this easy-to-use method is an effective therapeutic option for chronic ulcers. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - March 15, 2013 Category: Surgery Authors: Castana, O., Dimitrouli, A., Argyrakos, T., Theodorakopoulou, E., Stampolidis, N., Papadopoulos, E., Pallantzas, A., Stasinopoulos, I., Poulas, K. Tags: Case Report Source Type: research

PICO: A Revelation In Topical Negative Pressure Therapy?
The authors present the case of a 23-year-old paratrooper who was admitted to intensive therapy unit with florid meningococcal septicemia. Being young, fit, and well, he survived this acute episode with supportive therapy, antibiotics, and inotropes. He made a good recovery and was left with multiple wounds all over his body predominantly on the extensor aspects of his upper and lower limbs and torso. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - March 15, 2013 Category: Surgery Authors: Ahmad, Z., Davis, M., Das-Gupta, R. Tags: Case Report Source Type: research

Interobserver and Intraobserver Reproducibility of Plain X-Rays in the Diagnosis of Diabetic Foot Osteomyelitis
The purpose of this study was to analyze the interobserver and intraobserver variability in plain radiography in the diagnosis of diabetic foot osteomyelitis. A prospective observational study was performed from October 1, 2009, to July 31, 2011, on patients with diabetic foot ulcers, with clinically suspected osteomyelitis who were admitted to the Diabetic Foot Unit of the Complutense University of Madrid. Two professional groups examined 123 plain X-rays, each group comprising 3 different levels of clinical experience. To analyze intraobserver variability, 2 months later plain X-rays were reanalyzed by one of the clinica...
Source: The International Journal of Lower Extremity Wounds - March 15, 2013 Category: Surgery Authors: Alvaro-Afonso, F. J., Lazaro-Martinez, J. L., Aragon-Sanchez, J., Garcia-Morales, E., Cecilia-Matilla, A., Beneit-Montesinos, J. V. Tags: Translational Research Source Type: research

Increased Skin Inflammation and Blood Vessel Density in Human and Experimental Diabetes
Systemic inflammation is associated with impaired wound healing in diabetes mellitus (DM) patients. Using immunohistochemistry techniques, the authors investigated changes in skin inflammation and skin blood vessels in human and experimental diabetes. Comparing to the non-DM human subjects, the total number of inflammatory cells per biopsy and the number of inflammatory cells around blood vessels, a strong indication of inflammation, were higher in DM subjects irrespective of their risk for developing diabetic foot ulcer. Inflammatory cell infiltration was robustly increased in all DM animal models compared with their non-...
Source: The International Journal of Lower Extremity Wounds - March 15, 2013 Category: Surgery Authors: Tellechea, A., Kafanas, A., Leal, E. C., Tecilazich, F., Kuchibhotla, S., Auster, M. E., Kontoes, I., Paolino, J., Carvalho, E., Nabzdyk, L. P., Veves, A. Tags: Clinical and Experimental Science Source Type: research

Random thoughts
(Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - March 15, 2013 Category: Surgery Authors: Mani, R. Tags: Editorial Source Type: research