The International Journal of Lower Extremity Wounds This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Book Review: Fast Facts About Pressure Ulcer Care for Nurses: How to Prevent, Detect, and Resolve Them in a Nutshell
(Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - September 16, 2014 Category: Surgery Authors: Fletcher, J. Tags: Book Review Source Type: research

The Use of Negative Pressure in Critical Necrotizing Fasciitis Treatment: A Case Presentation
In conclusion, negative pressure treatment may help diminish toxin absorbance, detach gangrene tissue, and preserve sparing vital tissue. This case suggests the value of combined use of negative pressure therapy and conservative debridement in critically ill patients with extensive necrotizing fasciitis. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - September 16, 2014 Category: Surgery Authors: Ge, K., Xu, B., Wu, J.-J., Wu, M., Lu, S., Xie, T. Tags: Case Reports Source Type: research

Is Immobilization of the Ankle and Metatarsophalangeal Joint Effective in Suppressing the Spread of Infection in Diabetic Foot Ulcers?
Diabetics with foot-related problems might eventually need to undergo major or minor amputation because of infection or cellulites. It has been suggested that immobilization of the ankle and the metatarsophalangeal joint suppresses the spread of infection; however, there is no evidence to support this inference. Here, we demonstrate by histological analysis how the immobilization works. The tendon from the amputated toe is harvested, and a hematoxylin–eosin stained paraffin-embedded section is prepared and analyzed. Necrosis occurred in only a single fiber of the tendon, and intact and necrotic or infected tendon fib...
Source: The International Journal of Lower Extremity Wounds - September 16, 2014 Category: Surgery Authors: Sakakibara, S., Tsuji, Y., Hashikawa, K., Terashi, H. Tags: Case Reports Source Type: research

Lipid-Colloid Dressing Shows Improved Reepithelialization, Pain Relief, and Corneal Barrier Function in Split-Thickness Skin-Graft Donor Wound Healing
Donor-site wound healing was tested with a nonadherent petrolatum- and hydrocolloid-impregnated polyester, a lipid-colloid dressing, and a nonadherent polyester dressing, supplemented with petrolatum manually by a physician onsite. Ten patients, 1 woman and 9 men (22 to 79 years old; average 58.4 ± 17.54 years), were enrolled in this prospective comparison study. The split-thickness skin graft was 14.5 ± 7.49 cm long x 8.2 ± 4.07 cm wide (5.5-27 cm long and 4.0-14.0 wide) and 14/1000 inches (0.356 mm) deep. The degree of reepithelialization in lipid-colloid dressing was significantly better than that i...
Source: The International Journal of Lower Extremity Wounds - September 16, 2014 Category: Surgery Authors: Tanaka, K., Akita, S., Yoshimoto, H., Houbara, S., Hirano, A. Tags: Clinical and Experimental Research Source Type: research

Minor Amputation and Palliative Wound Care as a Strategy to Avoid Major Amputation in Patients With Foot Infections and Severe Peripheral Arterial Disease
Foot infections occurring in patients with severe peripheral arterial disease (PAD) who are not considered candidates for revascularization and limb salvage efforts are generally treated with major amputations. Herein we describe our early experiences in managing foot infections with minor amputations and palliative wound care as a strategy to avoid the functional disability often associated with major amputations. Patients with severe PAD that underwent minor amputations and subsequent palliative wound care for moderate/severe infections were paired with age-matched controls with PAD that underwent primary major amputatio...
Source: The International Journal of Lower Extremity Wounds - September 16, 2014 Category: Surgery Authors: Barshes, N. R., Gold, B., Garcia, A., Bechara, C. F., Pisimisis, G., Kougias, P. Tags: Clinical and Translational Research Source Type: research

Clinical Outcomes of Multidrug Resistant Pseudomonas aeruginosa Infection and the Relationship With Type III Secretion System in Patients With Diabetic Foot
The objective was to analyze the clinical outcomes of multidrug resistant Pseudomonas aeruginosa (MDRPA) infection and determine the relationship between type III secretion system (TTSS) and MDRPA in diabetic foot (DF) patients. A total of 117 patients infected with P aeruginosa were recruited and grouped into MDRPA and non-MDRPA group according to antimicrobial susceptibility testing. TTSS genes were detected by polymerase chain reaction (PCR). Potential risk factors for MDRPA infection were examined using univariate and multivariate analyses. Clinical outcomes were compared on the basis of MDRPA or TTSS virulence gene. P...
Source: The International Journal of Lower Extremity Wounds - September 16, 2014 Category: Surgery Authors: Zhang, J., Chu, Y., Wang, P., Ji, X., Li, X., Wang, C., Peng, Y. Tags: Clinical and Translational Research Source Type: research

Gender Differences of Lower Extremity Amputation Risk in Patients With Diabetic Foot: A Meta-Analysis
In conclusion, our meta-analysis indicates that men with diabetic foot have about one half increased amputation risk than women with diabetic foot. Men with diabetes should receive more complete follow-up and more adequate health education. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - September 16, 2014 Category: Surgery Authors: Tang, Z.-Q., Chen, H.-L., Zhao, F.-F. Tags: Clinical and Translational Research Source Type: research

High Matrix Metalloproteinase Levels Are Associated With Dermal Graft Failure in Diabetic Foot Ulcers
The aim of our study is to analyze factors, including matrix metalloproteinase (MMP) levels, that could influence the integration of dermal grafts in diabetic foot ulcers. From September 2012 to September 2013, 35 diabetic patients with IIA lesion (Texas Wound Classification) and an extensive foot tissue loss were considered suitable for dermal graft. Before the enrollment we ensured the best local conditions: adequate blood supply, control of infection, and offloading. The MMP level of each lesion was evaluated blindly before the application of dermal substitutes. At 1-month follow-up, we analyzed the correlation between ...
Source: The International Journal of Lower Extremity Wounds - September 16, 2014 Category: Surgery Authors: Izzo, V., Meloni, M., Vainieri, E., Giurato, L., Ruotolo, V., Uccioli, L. Tags: Clinical and Translational Research Source Type: research

Role of Polymeric Biomaterials as Wound Healing Agents
In uncontrolled hemorrhage, the main cause of death on the battlefield and in accidents, half of the deaths are caused by severe blood loss. Polymeric biomaterials have great potential in the control of severe hemorrhage from trauma, which is the second leading cause of death in the civilian community following central nervous system injuries. The intent of this article is to provide a review on currently available biopolymers used as wound dressing agents and to describe their best use as it relates to the condition and type of the wound (acute, chronic, superficial, and full thickness) and the phases of the wound healing...
Source: The International Journal of Lower Extremity Wounds - September 16, 2014 Category: Surgery Authors: Agrawal, P., Soni, S., Mittal, G., Bhatnagar, A. Tags: Original Review Source Type: research

Transformation of the Multidisciplinary Diabetic Foot Clinic Into a Multidisciplinary Diabetic Foot Day Unit: Results From a Service Evaluation
The natural history of the diabetic foot is aggressive and complex. To counteract this, we describe the transformation of a Multidisciplinary Diabetic Foot Clinic into a Multidisciplinary Diabetic Foot Day Unit, which delivers an emergency open access system for patients, with a "one-stop," same day service in which investigations are performed, results reviewed and treatment implemented. It also provides joint clinics with vascular, orthopaedic, and plastic surgeons and specialized clinics for casting of complex neuropathic feet and for the administration of intravenous or intramuscular antibiotics on the same day. The ai...
Source: The International Journal of Lower Extremity Wounds - September 16, 2014 Category: Surgery Authors: Manu, C. A., Mustafa, O. G., Bates, M., Vivian, G., Mulholland, N., Elias, D., Huang, D. Y., Deane, C., Cavale, N., Kavarthapu, V., Rashid, H., Edmonds, M. Tags: Clinical Research Source Type: research

How to Cope With the Increasing Burden of the Diabetic Foot: "Better Three Hours Too Soon Than a Minute Too Late"
(Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - September 16, 2014 Category: Surgery Authors: Papanas, N., Mani, R. Tags: Editorial Source Type: research

Genetic Alterations in Toll-Like Receptor 4 Signaling Pathway and Impairment of Wound Healing in Patients With Type 2 Diabetes
(Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - June 13, 2014 Category: Surgery Authors: Singh, K., Singh, V. K., Agrawal, N. K., Gupta, S. K., Singh, K. Tags: Letter to the Editor Source Type: research

Bosentan and Extracorporeal Photochemotherapy in Eosinophilic Fasciitis: Synergistic Action or Fortuitous Coincidence?
(Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - June 13, 2014 Category: Surgery Authors: Pileri, A., Odorici, G., Giudice, V., Patrizi, A., Bardazzi, F. Tags: Letter to the Editor Source Type: research

Management of a Patient With Faciocervical Burns and Inhalational Injury Due to Hydrofluoric Acid Exposure
Hydrofluoric acid, a highly dangerous substance, can cause tissue damage and systemic toxicity by its unique mechanisms. Many cases of severe faciocervical burns due to hydrofluoric acid exposure are lethal. Herein, we present a case of 37-year-old man who suffered from hydrofluoric acid burns to his face, anterior neck, lips, and nasal cavity. On admission, this patient coughed with much sputum, and the chest auscultation detected rough breath sounds, wheezes, and very weak heart sounds, indicating possible inhalation injury. This case highlights the extreme complexity of managing this kind of injury. Timely and accurate ...
Source: The International Journal of Lower Extremity Wounds - June 13, 2014 Category: Surgery Authors: Yuanhai, Z., Xingang, W., Liangfang, N., Chunmao, H. Tags: Case Report Source Type: research

Pretibial Myxedema: Case Presentation and Review of Treatment Options
We present a 57-year-old woman with 12-month history of PM, which occurred a year after treatment of Graves’ disease and improved with topical corticosteroids, support stockings, and intralesional steroid injections until recurrence with local erythema and woody edema. A literature review was undertaken of the evidence-based treatment modalities for symptomatic PM: although commonly asymptomatic and self-limited, severe cases of PM may be treated with topical corticosteroid, compressive therapy, and intralesional corticosteroid injections. (Source: The International Journal of Lower Extremity Wounds)
Source: The International Journal of Lower Extremity Wounds - June 13, 2014 Category: Surgery Authors: Kim, W. B., Mistry, N., Alavi, A., Sibbald, C., Sibbald, R. G. Tags: Case Report Source Type: research