aPDT for periodontitis treatment in ovariectomized rats under systemic nicotine
The simultaneous effects of nicotine and oestrogen deficiency on the periodontal repair are unknown. aPDT and LLLT were compared as adjunctive to SRP for the treatment of EP in ovariectomized rats under nicotine. LLLT and aPDT minimized the deleterious effects of nicotin to regulate the inflammatory response and RANK/RANKL/OPG system. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - February 23, 2018 Category: Laser Surgery Authors: Valdir Gouveia Garcia, Erivan Clementino Gualberto, Edilson Ervolino, Maria Jos é Hitomi Nagata, Juliano Milanezi de Almeida, Letícia Helena Theodoro Source Type: research

Multifunctional manganese-doped Prussian blue nanoparticles for two-photon photothermal therapy and magnetic resonance imaging
Prussian Blue (PB) type nanoparticles are a new family of inorganic nano-objects made of transition metal ions or lanthanides assembled through cyano-bridging ligands in nano-sized architectures. They have attracted a great deal of interest during the past ten years due to their specific molecule-based nature that is different compared to conventional inorganic nanoparticles [1 –4]. They present a remarkable potential for biomedical applications due to many advantages from their flexible molecule-based structure, adjustable composition, tunable physical and chemical properties, porosity, high stability in aqueous media e...
Source: Photodiagnosis and Photodynamic Therapy - February 22, 2018 Category: Laser Surgery Authors: Lamiaa M.A. Ali, Emna Mathlouthi, Marilyn Kajdan, Morgane Daurat, J érôme Long, Rahima Sidi-Boulenouar, Maïda Cardoso, Christophe Goze-Bac, Nourredine Amdouni, Yannick Guari, Joulia Larionova, Magali Gary-Bobo Source Type: research

How to choose among the multiple options to enhance the penetration of topically applied methyl aminolevulinate prior to photodynamic therapy
I have read with interest the paper by Osman-Ponchet et al. [1] comparing the in vitro penetration of methyl aminolevulinate (MAL) into ex vivo human skin pre-treated with an abrasive pad or a microneedling device. The authors have found that abrasion with skin preparation pad is superior to microneedling for increasing MAL penetration in ex vivo human skin. These observations seem to lead to the conclusion that skin should be pre-treated prior to MAL photodynamic therapy (PDT) with an abrasive pad instead of a microneedling device. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - February 22, 2018 Category: Laser Surgery Authors: Valerio De Vita Tags: Letter to the editor Source Type: research

Multifunctional manganese-doped Prussian blue nanoparticles for two-photon Photothermal Therapy and Magnetic Resonance Imaging
(Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - February 22, 2018 Category: Laser Surgery Authors: Lamiaa M.A. Ali, Emna Mathlouthi, Marilyn Kajdan, Morgane Daurat, J érôme Long, Rahima Sidi-Boulenouar, Maïda Cardoso, Christophe Goze-Bac, Nourredine Amdouni, Yannick Guari, Joulia Larionova, Magali Gary-Bobo Source Type: research

How to choose among the multiple options to enhance the penetration of topically applied methyl aminolevulinate prior to photodynamic therapy
(Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - February 22, 2018 Category: Laser Surgery Authors: Valerio De Vita Tags: Letter to the editor Source Type: research

Effective phthalocyanines mediated photodynamic therapy with doxorubicin or methotrexate combination therapy at sub-micromolar concentrations in vitro
One of the leading causes of death in developed countries is cancer, and it is currently at the second position in developing countries after cardiovascular diseases [1]. In 2015 in the United States a new diagnosis was given to up to 12,900 cervical-, 22,850 brain- and 234,190 breast-cancer patients alone, among the total of over 1.6 million cancers being diagnosed [2]. In Pakistan breast and cervical cancer combined are the leading causes of death in females, reaching 1 out of 9 women being affected by breast cancer. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - February 21, 2018 Category: Laser Surgery Authors: Safdar Ali, Saleh Muhammad, Ahmat Khurshid, Masroor Ikram, Muhammad Maqsood, Carl Fisher, Judy Cathcart, Lothar Lilge Source Type: research

Superficial resection combined with photodynamic therapy for successful treatment of facial lupus vulgaris with squamous cell carcinoma
A 65  year-old female presented with right facial patches for 30 years and a lump for half a year with slight itch and pain. She had accepted irregular topical steroid and antibiotic treatment in local hospital. Dermatological examination revealed a large area of dark red patches in the right face, w ith a 4cm × 3cm × 1 cm lump and blood scab on the surface (Fig. 1). The patient denied any history of other diseases. Pathology examination showed excessive epidermal cornification, mild acanthosis hyperplasia, partial ulcer formation, diffuse squamous-cell mass infiltration in dermal su perficial layer, distin...
Source: Photodiagnosis and Photodynamic Therapy - February 21, 2018 Category: Laser Surgery Authors: Qian Zhang, Xiulian Xu, Rong Zeng, Wenbo Bu, Fang Fang Tags: Case report Source Type: research

Effective Phthalocyanines mediated Photodynamic Therapy with Doxorubicin or Methotrexate combination therapy at sub-micromolar concentrations in vitro
(Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - February 21, 2018 Category: Laser Surgery Authors: Safdar Ali, Saleh Muhammad, Ahmat Khurshid, Masroor Ikram, Muhammad Maqsood, Carl Fisher, Judy Cathcart, Lothar Lilge Source Type: research

Superficial resection combined with photodynamic therapy for successful treatment of facial lupus vulgaris with squamous cell carcinoma
(Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - February 21, 2018 Category: Laser Surgery Authors: Qian Zhang, Xiulian Xu, Rong Zeng, Wenbo Bu, Fang Fang Tags: Case report Source Type: research

Photonic technology for the treatments of venous and arterial ulcers: Case report
In this report, we report a case study on a 50-year-old male patient with different chronic wounds, such as venous ulcer and arterial ulcer in both legs. These wounds have persisted for more than 10 years, despite the different treatments applied, including, different dressings, hyperbaric camera, as well as the used of several medicines of oral and topical application. The case is addressed with the aim to evaluate if treatment that uses combined techniques such as low level laser therapy (LLLT), photodynamic therapy and cellulose membrane is able to improve healing and reduction of time of treatment in those types of chr...
Source: Photodiagnosis and Photodynamic Therapy - February 19, 2018 Category: Laser Surgery Authors: Fernanda Mansano Carbinatto, Antonio Eduardo de Aquino, Vit ória Helena Maciel Coelho, Vanderlei S. Bagnato Tags: Case report Source Type: research

Blue light versus red light for photodynamic therapy of basal cell carcinoma in patients with Gorlin syndrome: A bilaterally controlled comparison study
Basal cell nevus syndrome (BCNS; Gorlin; Gorlin-Goltz) is a chronic genetic condition characterized by basal cell carcinoma (BCC) skin tumors and odontogenic jaw cysts before the age of 20 years, palmar/plantar pitting, brain calcifications, various skeletal and soft tissue abnormalities, and a high risk for developing medulloblastoma 1 –4. Surgical treatment of multiple BCC tumors, starting in childhood and often numbering into the hundreds over a lifetime, causes extensive scarring that can be highly debilitating both functionally and psychologically 5. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - February 19, 2018 Category: Laser Surgery Authors: Edward V. Maytin, Urvashi Kaw, Muneeb Ilyas, Judith A. Mack, Bo Hu Source Type: research

Is adjunctive photodynamic therapy more effective than scaling and root planing alone in the treatment of periodontal disease in hyperglycemic patients? A systematic review
Periodontal disease (PD) is an inflammatory disease resulting in destruction and degradation of periodontal tissues. It is well accepted that pathogenic microorganisms initiate and progress periodontal diseases [1]. Therefore, reducing the load of pathogenic microorganisms and inhabited irritants are the primary therapeutic goals in the management of periodontal disease [2]. Non-surgical debridement in the form of scaling and root planning (SRP) in order to remove bacterial plaques and local irritants has been a key to treatment of periodontal disease [3,4]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - February 19, 2018 Category: Laser Surgery Authors: Fawad Javed, Danial Salehpoor, Talal Al-Dhafeeri, Muhammad Yousuf, Hans Malmstrom, Junad Khan, Zohaib Akram Tags: Review Source Type: research

Photonic technology for the treatments of venous and arterial ulcers: Case report
In this report, we report a case study on a 50-year-old male patient with different chronic wounds, such as venous ulcer and arterial ulcer in both legs. These wounds have persisted for more than 10 years, despite the different treatments applied, including, different dressings, hyperbaric camera, as well as the used of several medicines of oral and topical application. The case is addressed with the aim to evaluate if treatment that uses combined techniques such as low level laser therapy (LLLT), photodynamic therapy and cellulose membrane is able to improve healing and reduction of time of treatment in those types of chr...
Source: Photodiagnosis and Photodynamic Therapy - February 19, 2018 Category: Laser Surgery Authors: Fernanda Mansano Carbinatto, Antonio Eduardo de Aquino, Vit ória Helena Maciel Coelho, Vanderlei S. Bagnato Tags: Case report Source Type: research

Photonic technology for the treatments of the venous and arterial ulcers: Case report
In this report, we recent a case study on a 50-year-old male patient with different chronic wounds, such as venous ulcer and arterial ulcer in both legs. These wounds have persisted for more than 10 years, despite the different treatments applied, between safenectomy, different dressings, hyperbaric camera, as well as the used of several medicines of oral and topical application. The case is addressed with the aim to evaluate if treatment that uses combined techniques such as low level laser therapy (LLLT), photodynamic therapy and cellulose membrane is able to improve healing and reduction of time of treatment in those ty...
Source: Photodiagnosis and Photodynamic Therapy - February 19, 2018 Category: Laser Surgery Authors: Fernanda Mansano Carbinatto, Antonio Eduardo de Aquino, Vit ória Helena Maciel Coelho, Vanderlei S. Bagnato Tags: Case report Source Type: research