A Study for the Detection of Kidney Cancer Using Fluorescence Emission Spectra and Synchronous Fluorescence Excitation Spectra of Blood and Urine
Kidney cancer is one of the ten most common cancers in both men and women worldwide. The risk of developing life-threatening kidney cancer is about 1.6%. Smoking is a main contributing cause of kidney cancer development, with men being at higher risk than women [1]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 22, 2018 Category: Laser Surgery Authors: M. Atif, M.S. AlSalhi, S. Devanesan, V. Masilamani, K. Farhat, D. Rabah Source Type: research

Analysis of hepatitis B virus infection in blood sera using Raman spectroscopy and machine learning
This study presents the analysis of hepatitis B virus (HBV) infection in human blood serum using Raman spectroscopy combined with pattern recognition technique. In total 119 confirmed samples of HBV infected sera, collected from Pakistan Atomic Energy Commission (PAEC) general hospital have been used for the current analysis. The differences between normal and HBV infected samples have been evaluated using support vector machine (SVM) algorithm. SVM model with two different kernels i.e. polynomial function and Gaussian radial basis function (RBF) have been investigated for the classification of normal blood sera from HBV i...
Source: Photodiagnosis and Photodynamic Therapy - May 19, 2018 Category: Laser Surgery Authors: Saranjam Khan, Rahat Ullah, Asifullah Khan, Ruby Ashraf, Hina Ali, Muhammad Bilal, Muhammad Saleem Source Type: research

Synthesis of axially disubstituted silicon phthalocyanines and investigation of photodynamic effects on HCT-116 colorectal cancer cell line
Photosynthesis is one of the most important natural events for life on earth. This operation includes the accumulating of solar energy and its subsequent conversion into useful chemical energy by supramolecular natural systems. These supramolecular systems absorbs the energy of photons by antenna complexes and transfers the energy to the corresponding reaction centers. Synthetic light absorber antennas are quite engaging for chemists [1,2]. Photodynamic therapy (PDT) is a promising treatment method that is clinically approved in the treatment of cancer [3,4]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 15, 2018 Category: Laser Surgery Authors: Ceren Sar ı, Figen Celep Eyüpoğlu, İsmail Değirmencioğlu, Rıza Bayrak Source Type: research

Antimicrobial effect of photodynamic therapy using erythrosine/methylene blue combination on Streptococcus mutans biofilm
Photodynamic therapy (PDT) has emerged as an effective and promising alternative for the treatment of several clinical conditions such as cancer of the lung, head, neck, breast and skin [1,2,3,4], macular degeneration and other ophthalmological diseases [5]. In dentistry, PDT, also known as photodynamic inactivation or antimicrobial photodynamic therapy (aPDT), has been used in the diagnosis of malignant oral lesions, treatment of oral cancer, as well as the inactivation of microorganisms in bacterial or fungal infections [6]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 12, 2018 Category: Laser Surgery Authors: La íse Midori Tokubo, Pedro Luiz Rosalen, Janaina de Cássia Orlandi Sardi, Irlan Almeida Freires, Mitsue Fujimaki, Josely Emiko Umeda, Patricia Magalhães Barbosa, Gabriela Ortolan Tecchio, Noboru Hioka, Camila Fabiano de Freitas, Raquel Sano Suga Terad Source Type: research

Antimicrobial effect of the photodynamic therapy using erythrosine/methylene blue combination on Streptococcus mutans biofilm
Photodynamic therapy (PDT) has emerged as an effective and promising alternative for the treatment of several clinical conditions such as cancer of the lung, head, neck, breast and skin [1,2,3,4], and macular degeneration and other ophthalmological diseases [5]. In dentistry, PDT, also known as photodynamic inactivation or antimicrobial photodynamic therapy (aPDT), has been used in the diagnosis of malignant oral lesions, treatment of oral cancer, as well as the inactivation of microorganisms in bacterial or fungal infections [6]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 12, 2018 Category: Laser Surgery Authors: La íse Midori Tokubo, Pedro Luiz Rosalen, Janaina de Cássia Orlandi Sardi, Irlan Almeida Freires, Mitsue Fujimaki, Josely Emiko Umeda, Patricia Magalhães Barbosa, Gabriela Ortolan Tecchio, Noboru Hioka, Camila Fabiano de Freitas, Raquel Sano Suga Terad Source Type: research

Combining Magnetic Resonance Imaging (MRI) and Medical Infrared Thermography (MIT) in the pre- and per-operating management of severe Hidradenitis Suppurativa (HS)
Hidradenitis suppurativa (HS) is a chronic, inflammatory, and recurrent skin disease characterized by painful nodules, multiple abscesses, fistulas, sinus tracts, and scarring that has a predilection for apocrine gland-bearing sites [1 –3]. Anogenital manifestations may occur in up to 32% of HS patients. HS treatment involves topical and systemic drugs, but surgical excision of the involved follicles seems to be the only effective curative treatment and has the lowest recurrence rate (0% to 15%) [3–7]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 12, 2018 Category: Laser Surgery Authors: St éphane Derruau, Yohann Renard, Hervé Pron, Redha Taiar, Ellie Abdi, Guillaume Polidori, Sandrine Lorimier Source Type: research

Prediction of early caries prognosis after fluoride application based on the severity of lesions: An in situ study
In recent years, the concept of healthcare has changed to prevention and control of disease. This trend has led to a paradigm shift in health services management. Many individuals need more personalized caries management strategies, which focus on specific patient needs. In dentistry, for the successful prevention and management of dental caries, it is essential to detect carious lesions at an early stage, assess the pattern of recovery after preventive interventions, and provide an accurate prognosis. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 12, 2018 Category: Laser Surgery Authors: Hee-Eun Kim, Baek-Il Kim Source Type: research

Effect of phototherapy on shear bond strength of resin cements to zirconia ceramics: a systematic review and meta-analysis of in-vitro studies
The requirement for dental restorations with high strength and improved esthetic characteristics has raised to such an extent that ceramic materials will eventually substitute metal restorations in dentistry. Among dental ceramics, zirconia has gained high acceptance, and holds a leading position in metal-free dental restorations because of properties such as high strength, chemical stability, biocompatibility, and nontoxicity [1]. Recent progress in computer-aided design and computer-aided manufacturing (CAD/CAM) techniques has made zirconia an ideal and convenient choice for indirect restorations [2]. (Source: Photodiagn...
Source: Photodiagnosis and Photodynamic Therapy - May 11, 2018 Category: Laser Surgery Authors: Khulud Abdulrahman Al-Aali Source Type: research

Confocal Fluorescence Imaging To Evaluate The Effect Of Antimicrobial Photodynamic Therapy Depth On P. Gingivalis And T. Denticola Biofilms
Periodontal disease which is characterized by inflammatory processes resulting in bone loss induced primarily by bacterial stimulation. Porphyromonas gingivalis and Treponema denticola are two species that are identified as contributing to the i incidence of periodontal disease as well as peri-implantitis [1]. Studies [2 –4] show that these bacteria exhibit symbiotic growth in vitro and a synergistic [5] virulence in co-infection of animal models, and present a significant challenge to traditional antimicrobial treatment modalities [6]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 10, 2018 Category: Laser Surgery Authors: Stephen Rogers, Kiyonobu Honma, Thomas S. Mang Source Type: research

Photodynamic therapy in combination with ranibizumab versus ranibizumab monotherapy for wet age-related macular degeneration: A systematic review and meta-analysis
Age-related macular degeneration (AMD) is one of the prevailing causes of serious vision loss, mostly in people older than 55 years old in Western countries [1,2]. Characterized by choroidal neovascularization (CNV) [3], wet AMD covers about 20% of AMD patients, but it is responsible for almost 80%-90% severe vision loss [4 –8]. The intractability of wet AMD, however, lies in its relationships with age, metabolic changes in the retinal pigment epithelium, oxidative damage, especially light injury, inflammatory and immune disorders, genetic factors and so forth [4], confirming that AMD is an irreversible, chronic, deg ene...
Source: Photodiagnosis and Photodynamic Therapy - May 9, 2018 Category: Laser Surgery Authors: Yongxian Su, Jiawei Wu, Yu Gu Source Type: research

Cell death mechanisms in Leishmania amazonensis triggered by methylene blue-mediated antiparasitic photodynamic therapy
Leishmaniasis is an infectious disease caused by species of protozoa of the Leishmania genus that is transmitted by phlebotomine sand flies. Despite the variety of clinical manifestations, the most common form is cutaneous leishmaniasis (CL) following visceral leishmaniasis and mucosal leishmaniasis. Nowadays, leishmaniasis is endemic in at least 97 nations and territories, and there are over one million cases per year. More than 87% of the cases are reported in Africa, Middle West and Latin America, mainly in Brazil. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 8, 2018 Category: Laser Surgery Authors: D ébora P. Aureliano, José Angelo Lauletta. Lindoso, Sandra Regina de Castro Soares, Cleusa Fumika Hirata Takakura, Thiago Martini Pereira, Martha Simões Ribeiro Source Type: research

Can red-light 5-aminolevulinic photodynamic therapy cure port wine stains on comb animal model?
The nevus flammeus, also named port wine stains(PWS), is congenital venous malformation and common congenital papillary telangiectasia [1,2]. Now, the pulsed dye laser (PDL) is the ‘gold standard’ for the treatment of PWS [3]. But it is mainly used in superficial PWS. For large area PWS, the curative effect is not ideal due to the defects of careless operation, easy scarring and recurring. With the development of technology, photodynamic therapy(PDT) is used successfully t o treat PWS. Compared with PDL, PDT has higher selectivity, which is especially suitable for the treatment of PWS in large area. (Source: Photodiagn...
Source: Photodiagnosis and Photodynamic Therapy - May 5, 2018 Category: Laser Surgery Authors: Yongxian Lai, Haiyan Zhang, Minglei Wei, Jie Ji, Lei Shi, Peiru Wang, Bo Wang, Zheng Huang, Xiuli Wang Source Type: research

Effect of antimicrobial photodynamic therapy in open flap debridement in the treatment of peri-implantitis: A randomized controlled trial
Peri-implant diseases are a group of inflammatory processes which are characterized by bleeding and/or suppuration (peri-implant mucositis) and if untreated, may lead to radiographic evidence of bone loss around dental implants [peri-implantitis (PI)] [1,2]. A group of bacteria has been associated with peri-implant destruction [3]. The complex microbiota poses a clinical challenge for clinicians in the treatment of PI. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 5, 2018 Category: Laser Surgery Authors: Abdulaziz M. Albaker, Aws S. ArRejaie, Mohammed Alrabiah, Khulud Abdulrahman Al-Aali, Sameer Mokeem, Mohammed N. Alasqah, Fahim Vohra, Tariq Abduljabbar Source Type: research

Photodynamic therapy of necrobiosis lipoidica using methyl aminolevulinate: a retrospective follow-up study
Necrobiosis lipoidica (NL) is a rare uncommon, granulomatous skin disease of unknown origin. Clinically, NL appears as irregular or circular lesions ranging in colour from brown to dark purple [1]. The disease is characterized by degenerative changes in dermal collagen, inflammation, and impaired microcirculation leading to thickening of the blood vessels [2]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 4, 2018 Category: Laser Surgery Authors: Jeanette Kaae, Peter Alshede Philipsen, Hans Christian Wulf Source Type: research

Photodynamic therapy as an alternative to antibiotic therapy for the treatment of infected leg ulcers
Chronic leg ulcers are a significant global problem affecting 1% of the adult population and occurring even in 4% of patients aged 65 years and older. Billions of dollars are spent every year to provide care to patients with these often difficult to heal and recurrent chronic wounds. Regardless of the etiology of chronic wounds, their treatment is usually a difficult, long-lasting process with a serious risk of microbial invasion that might finally lead to serious complications, such as slow healing, devastating pain, extension of wound size and systemic illness [1]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 3, 2018 Category: Laser Surgery Authors: Aleksandra Kawczyk-Krupka, Barbara Pucelik, Anna Mi ędzybrodzka, Aleksander Sieroń, Janusz M. Dąbrowski Tags: Review Source Type: research