Photodiagnosis and Photodynamic Therapy This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Effect of Antimicrobial Photodynamic Therapy on Microleakage of Class V Cavities Restored with Composite Resin
Cariogenic bacteria are responsible for development of dental caries. They ferment the carbohydrates adhered to dental surfaces and produce acids, which cause demineralization and lead to development of carious lesions. Streptococcus mutans (S. mutans) and Lactobacillus acidophilus are commonly isolated from dental biofilms. Dental caries may be prevented by decreasing the count of these bacteria [1]. Chemical agents such as chlorhexidine and ethylenediaminetetraacetic acid are used to eliminate bacteria following cavity preparation or root canal instrumentation in order to prevent microbial reinfection [2]. (Source: Photo...
Source: Photodiagnosis and Photodynamic Therapy - June 12, 2018 Category: Laser Surgery Authors: Ladan Madani, Edwin Sarkisians, Nazanin Kiomarsi, Mohammad Javad Kharazi Fard, Nasim Chiniforush Source Type: research

Anti-angiogenic treatment (Bevacizumab) improves the responsiveness of photodynamic therapy in colorectal cancer
Photodynamic therapy (PDT) is a new treatment utilizing the combined action of photosensitizers and light for the treatment of various cancers. PDT for cancer involves the administration of photosensitizers to solid tumors and local illumination with light of a specific wavelength, depending on the photosensitizer. Generally, longer wavelengths are preferred because they are able to penetrate more deeply into tissues and singlet oxygen or superoxide is generated by the PDT from molecular oxygen to destroy the cancer cells. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - June 9, 2018 Category: Laser Surgery Authors: Cheng-Liang Peng, Hua-Ching Lin, Wei-Lun Chiang, Ying-Hsia Shih, Ping-Fang Chiang, Tsai-Yueh Luo, Chun-Chia Cheng, Ming-Jium Shieh Source Type: research

Assessment of the actual light dose in photodynamic therapy
The importance of photodynamic therapy (PDT) in medicine is indisputable. The fields of application of PDT are growing fast attracting many scientists with different backgrounds leading to a myriad of treatments protocols [1,2]. Concerning the pre-clinical studies, the Web of Science database shows more than one thousand articles only in the last three years, from the date of this manuscript, reporting in vitro studies with PDT. Such multidisciplinary field and the extensive number of protocols involving different photosensitizers and light sources are in the origin of one of the major concerns in PDT: the correct assessme...
Source: Photodiagnosis and Photodynamic Therapy - June 9, 2018 Category: Laser Surgery Authors: Fabio A. Schaberle Source Type: research

Long-term clinical outcome in patients with high-grade soft tissue sarcoma who were treated with surgical adjuvant therapy using acridine orange after intra-lesional or marginal resection
Adequate surgical margins inhibit local tumor recurrence in high-grade soft tissue sarcomas (STSs) [1 –3]. However, if tumors are in close contact with major nerves, vessels, bones, or joints, patients can develop serious dysfunction of the affected limb after wide resection, which might involve the sacrifice of some or all those structures. Adjuvant radiotherapy (RT) may be performed when surgeon s perform dissection between tumors and these structures with marginal or intra-lesional resections to maintain limb function [1,4–6]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - June 7, 2018 Category: Laser Surgery Authors: Tomoki Nakamura, Katsuyuki Kusuzaki, Takao Matsubara, Hiroaki Murata, Tomohito Hagi, Kunihiro Asanuma, Akihiro Sudo Source Type: research

A Clinical Study of HMME-PDT Therapy in Chinese Pediatric patients with Port-wine stain
To report our observations from a trial of the effectiveness and safety of hematoporphyrin monomethyl ether photodynamic therapy (HMME-PDT) in treating Chinese Pediatric patients port-wine stains (PWS). (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - June 7, 2018 Category: Laser Surgery Authors: Gan Li-qiang, Wang Hua, Ni Si-li, Tan Chun-hua Source Type: research

Targeted Photodynamic-Induced Singlet Oxygen Production by Peptide-Conjugated Biodegradable Nanoparticles for Treatment of Skin Melanoma
(Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - June 7, 2018 Category: Laser Surgery Authors: Aya Ahmed Sebak, Iman Imam Gomaa, Aliaa Nabil ElMeshad, Mahmoud Hashem AbdelKader Source Type: research

Resolution of Herpes Simplex in the Nose Wing Region using Photodynamic Therapy and Photobiomodulation
Herpes simplex virus-1 (HSV-1) is a DNA virus in the family Herpes viridae that causes primary herpetic gingivostomatitis and mucocutaneous lesions in the orofacial region including lips, nose, mouth and eyes [1,2,3]. The patients notice distinct stages as prodrome due to tingling, itching or burning followed by a papule that progresses to being vesicular, crusted and healing [1,4]. The infection could affect children, adolescents and young adults [3] by being transmitted via direct contact with infected secretions [1]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - June 7, 2018 Category: Laser Surgery Authors: Andr éa Dias Neves Lago, Guilherme Silva Furtado, Odalace Chaves Ferreira, Rafael Soares Diniz, Letícia Machado Gonçalves Tags: Case report Source Type: research

Adjunctive use of antimicrobial photodynamic therapy in the treatment of medication-related osteonecrosis of the jaws: A case report
Antiresorptive agents and angiogenesis inhibitors are commonly administered to the osteoporosis patient population. Despite numerous advantages, bisphosphonates and human monoclonal antibodies have been associated with medication-related osteonecrosis of the jaws (MRONJ) in osteoporotic patients who underwent oral surgery procedures [1]. In addition to the intake of antiresorptive or antiangiogenic agents, MRONJ is characterized by exposed bone or bone that can be probed through intraoral or extraoral fistulae in the maxillofacial region that has persisted for more than 8 weeks, with no history of radiation therapy or obvi...
Source: Photodiagnosis and Photodynamic Therapy - June 6, 2018 Category: Laser Surgery Authors: Pier Paolo Poli, Francisley Ávila Souza, Carlo Maiorana Tags: Case report Source Type: research

Enhanced photocytotoxicity induced by a platinum diimine complex employing amine-functionalized magnetite-silica nanocomposites as delivery vehicles
Photodynamic therapy (PDT) is a therapeutic modality for cancer diagnosis and treatment of various types of tumors [1]. PDT usually consists of three components: a photosensitizer, light, and tissue oxygen. The light-activated photosensitizer transfers its excited-state energy to the surrounding oxygen, leading to the generation of cytotoxic singlet oxygen or other reactive oxygen species in targeted cells and consequently to cancer cell death and tissue devastation. In comparison with the conventional cancer treatment methods, PDT has some unique advantages such as minimal invasiveness and repeatability without cumulative...
Source: Photodiagnosis and Photodynamic Therapy - June 2, 2018 Category: Laser Surgery Authors: Zhigang Zhang, Yantao Zhu, Ruihui Dai, Yinghong Zhang, Hongfei Wang, Jiangang Li Source Type: research

Improved photodynamic efficacy of thiophenyl sulfonated zinc phthalocyanine loaded in lipid nano-carriers as new formulation for hepatocellular carcinoma cancer cells
Photodynamic therapy (PDT) is a modality for malignant and non-malignant disorders that has attracted a great interest in the last decades due to its high degree of specificity and selectivity [1 –3]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - June 2, 2018 Category: Laser Surgery Authors: Doaa A. Abdel Fadeel, Ghada Muneer, Asma M. Elsharif, Suhailah S. Al-Jameel, Hanan H. Mohamed, Tamer E. Youssef Source Type: research

Optical diagnosis of dentin caries lesions using Quantitative Light-induced Fluorescence technology
The precise diagnosis of dental caries and determination of their severity are very important factors when planning for treatment. For the assessment of caries, traditional diagnostic techniques have low sensitivities of only 30% for early occlusal surface caries and 50% for dentin caries. This low diagnostic power of traditional methods could increase in the ambiguity of clinical decision about some borderline lesions. For example, there is a large variation in removing the extent of the residual caries lesions which is closed to the pulp tissue. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 25, 2018 Category: Laser Surgery Authors: Jeong-Woo Lee, Eun-Song Lee, Baek-Il Kim Tags: Case report Source Type: research

The benefits of targeted endoscopic biopsy performed using the autofluorescence based diagnostic technique in 67 cases of diagnostically difficult gastrointestinal tumors
The search for new diagnostic and therapeutic procedures is an essential task in contemporary oncology [1 –3]. The prevention of the development of gastrointestinal cancer, in particular the detection and resection of polyps, is the reason why screening endoscopy is conducted. Endoscopic methods are, and will continue to be, the gold standard diagnostic tool in the diagnosis of organic gastrointestina l diseases as, apart from the actual imaging of available sections of the gastrointestinal tract, they also allow for targeted biopsy of pathological changes. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 25, 2018 Category: Laser Surgery Authors: Wojciech Latos, Aleksander Siero ń, Grzegorz Cieślar, Aleksandra Kawczyk-Krupka Source Type: research

Evaluation of red light scattering in gingival tissue – in vivo study
Rua Vergueiro 235/249 - Liberdade - S ão Paulo – Brazil – ZIP: 01504-001 (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 25, 2018 Category: Laser Surgery Authors: Let ícia Heineck Alvarenga, Martha Simões Ribeiro, Ilka Tiemy Kato, Silvia Cristina Núñez, Renato Araujo Prates Tags: Short Communication Source Type: research

Proteomic analysis reveals that pheophorbide a-mediated photodynamic treatment inhibits prostate cancer growth by hampering GDP-GTP exchange of ras-family proteins
Photodynamic treatment (PDT) is a promising modality in delivering focused treatment in primary and post-radiotherapy prostate cancer patients. It aims to eradicate cancer lesion but minimise damage to adjacent structures and hence helps in the preservation of urinary, sexual, and bowel functions [1]. PDT involves activation of a photosensitizer (PS) by light of a specific wavelength, generating transient levels of reactive oxygen species (ROS). PSs that have been studied, mainly include hematoporphyrin derivatives (Photofrin), aminolevulinic acid (5-ALA), verteporfin (visudyne), and chlorophyll derivatives (pheophorbide a...
Source: Photodiagnosis and Photodynamic Therapy - May 22, 2018 Category: Laser Surgery Authors: Dan Dan Xu, Chong Bing Xu, Hon Ming Lam, Fuk-Ling Wong, Albert Wing Nang Leung, Merrin Man Long Leong, William Chi Shing Cho, Robin Hoeven, Lv Qing Tao, Rong Rong Source Type: research

Antimicrobial photodynamic therapy associated with partial removal of carious tissue in a patient with amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) may have both spinal and bulbar manifestations, affects upper and lower limbs, resulting in respiratory insufficiency [1], difficulty gait and muscle paralysis [2]. In this way, functional alterations characterize ALS. Initially occurs in the lower limbs, progressing to the upper limbs until reaching the bulbar muscles [3]. This condition is often debilitating preventing the affected person of performing daily tasks on its own. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - May 22, 2018 Category: Laser Surgery Authors: Elizi ário Vitoriano de Araújo Neto, Alinne Patierry Oliveira Pacífico Feitosa, Giovanni Iury Martins Pontes, Luiz Carlos Costa Madeira Alves Tags: Case report Source Type: research