Long-term clinical outcome in patients with high-grade soft tissue sarcoma who were treated with surgical adjuvant therapy using acridine orange after intra-lesional or marginal resection

Adequate surgical margins inhibit local tumor recurrence in high-grade soft tissue sarcomas (STSs) [1 –3]. However, if tumors are in close contact with major nerves, vessels, bones, or joints, patients can develop serious dysfunction of the affected limb after wide resection, which might involve the sacrifice of some or all those structures. Adjuvant radiotherapy (RT) may be performed when surgeon s perform dissection between tumors and these structures with marginal or intra-lesional resections to maintain limb function [1,4–6].

Source: Photodiagnosis and Photodynamic Therapy - June 7, 2018 Category: Laser Surgery Authors: Tomoki Nakamura, Katsuyuki Kusuzaki, Takao Matsubara, Hiroaki Murata, Tomohito Hagi, Kunihiro Asanuma, Akihiro Sudo Source Type: research