Photodynamic inactivation assisted by localized surface plasmon resonance of silver nanoparticles: in vitro evaluation on Escherichia coli and Streptococcus mutans
Light-based therapy and diagnosis are essential non-invasive tools on medical and biomedical applications. The interaction of light with biological tissue can be prompted with the use of external agents, as photosensitizers, dyes, scatters, and fluorescent particles [1,2]. In particular, photodynamic inactivation (PDI) has been extensively used as a promising antimicrobial approach since it does not promote the selection of mutant resistant strains [3,4]. PDI explores the light-interaction with specific photosensitizers (PSs) to induce oxidative stress on microorganism, leading to cell death via different targets [5,6]. (S...
Source: Photodiagnosis and Photodynamic Therapy - April 17, 2018 Category: Laser Surgery Authors: Martha S. Ribeiro, Luciana S.A. de Melo, Sajid Farooq, Alessandra Baptista, Ilka T. Kato, Silvia C. N úñez, Renato E. de Araujo Source Type: research

Photodynamic inactivation of Candida ssp. on denture stomatitis. A clinical trial involving palatal mucosa and prosthesis disinfection
Candida-associated denture stomatitis (DS), also known as chronic atrophic candidiasis, is the most common oral fungal infection in individuals with dentures [1,2]. The etiology of DS is multifactorial and its occurrence is associated with poor adaptation of the removable denture (complete or partial), non-removal of it for long periods (e.g. during the night) and its inadequate hygiene. However, the presence of Candida spp. biofilm on the prosthesis is considered the most important factor for the establishment of DS [3]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - April 17, 2018 Category: Laser Surgery Authors: Andr é M. de Senna, Martha M.F. Vieira, Rosa Maria Machado-de-Sena, Aparecido O. Bertolin, Silvia C. Núñez, Martha S. Ribeiro Source Type: research

Photodynamic inactivation assisted by localized surface plasmon resonance of silver nanoparticles: in vitro evaluation on Escherichia coli and Streptococcus mutans
Light-based therapy and diagnosis are essential non-invasive tools on medical and biomedical applications. The interaction of light with biological tissue can be prompted with the use of external agents, as photosensitizers, dyes, scatters, and fluorescent particles [1,2]. In particular, photodynamic inactivation (PDI) has been extensively used as a promising antimicrobial approach since it does not promote the selection of mutant resistant strains [3,4]. PDI explores the light-interaction with specific photosensitizers (PSs) to induce oxidative stress on microorganism, leading to cell death via different targets [5,6]. (S...
Source: Photodiagnosis and Photodynamic Therapy - April 17, 2018 Category: Laser Surgery Authors: Martha S. Ribeiro, Luciana S.A. de Melo, Sajid Farooq, Alessandra Baptista, Ilka T. Kato, Silvia C. N úñez, Renato E. de Araujo Source Type: research

Photodynamic inactivation of Candida ssp. on denture stomatitis. A clinical trial involving palatal mucosa and prosthesis disinfection
Candida-associated denture stomatitis (DS), also known as chronic atrophic candidiasis, is the most common oral fungal infection in individuals with dentures [1,2]. The etiology of DS is multifactorial and its occurrence is associated with poor adaptation of the removable denture (complete or partial), non-removal of it for long periods (e.g. during the night) and its inadequate hygiene. However, the presence of Candida spp. biofilm on the prosthesis is considered the most important factor for the establishment of DS [3]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - April 17, 2018 Category: Laser Surgery Authors: Andr é M. de Senna, Martha M.F. Vieira, Rosa Maria Machado-de-Sena, Aparecido O. Bertolin, Silvia C. Núñez, Martha S. Ribeiro Source Type: research

Photodynamic therapy with topical photosensitizers in mucosal and semimucosal areas: review from a dermatologic perspective
Photodynamic therapy (PDT) has been defined a “2-step” procedure based on the interaction between a Photo Sensitizer (PS), a light source with a wavelength specific for that PS and environmental oxygen. PS, after being internalised into cells, activates in response to energy received from the light source and produces cytotoxic species in t he presence of oxygen. These radicals induce a plethora of biochemical intracellular processes that secondarily lead to cell death, either by apoptosis or by necrosis [1–3]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - April 15, 2018 Category: Laser Surgery Authors: Vieri Grandi, Maurizio Sessa, Luigi Pisano, Riccardo Rossi, Arturo Galvan, Riccardo Gattai, Moira Mori, Luana Tiradritti, Stefano Bacci, Giuliano Zuccati, Pietro Cappugi, Nicola Pimpinelli Source Type: research

Optical techniques for the diagnosis and treatment of lesions induced by the human papillomavirus — A resource letter
Human papillomaviruses (HPV) are the most common sexually-transmitted virus, and are responsible for diseases such as non-oncologic condyloma acuminatum. Carcinogenic HPV strains, are reported to be responsible for virtually all cases of cervical cancer and its precursor, the cervical intraepithelial neoplasia (CIN), due to the tropism of this virus for the squamocolumnar junction. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - April 11, 2018 Category: Laser Surgery Authors: Natalia Mayumi Inada, Hilde Harb Buzza, Fernanda Mansano Carbinatto, Kate Cristina Blanco, Cintia Teles de Andrade, Jos é Dirceu Vollet-Filho, Vanderlei Salvador Bagnato, Ron R. Allison Source Type: research

Treatment of Periodontitis in Smokers with Multiple Sessions of Antimicrobial Photodynamic Therapy or Systemic Antibiotics: A Randomized Clinical Trial
Clinical studies have repeatedly demonstrated that metronidazole (MTZ) plus amoxicillin (AMX) in conventional mechanical therapy is beneficial [1 –8]. Despite the proven benefits, this specific indication remains controversial in different clinical situations, especially in relation to other elements of periodontal therapy [9]. Restraint in the antibiotics use in periodontal therapy has been recommended. Nevertheless, further research is ne eded to assess the true impact of antibiotics use in periodontal therapy on the development of antibiotics resistance [10]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - April 10, 2018 Category: Laser Surgery Authors: Let ícia Helena Theodoro, Naida Zanini Assem, Mariéllen Longo, Márcio Luiz Ferro Alves, Cristiane Duque, Rafael Nobrega Stipp, Natália Leal Vizoto, Valdir Gouveia Garcia Source Type: research

ALA-PDT as palliative care in a patient with secondary perineum EMPD
Extramammary Paget ’s disease (EMPD) is an uncommon intra-epidermal carcinoma of apocrine gland-bearing skin, which is divided into primary and secondary EMPD based on whether there is an underlying malignancy [1,2]. Exploring the valuable immunological markers of primary and secondary EMPD is of great significance. Asking about the patient's past medical history in detail and proper auxiliary means of inspection also count for a lot, which may help find out the root cause of the disease and opt for appropriate treatment strategy. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - April 5, 2018 Category: Laser Surgery Authors: Shuzhan Shen, Guolong Zhang, Peiru Wang, Yunfeng Zhang, Uma Keyal, Jie Ji, Xiuli Wang Tags: Case report Source Type: research

In vitro photodynamic inactivation effects of benzylidene cyclopentanone photosensitizers on clinical fluconazole-resistant Candida albicans
Candida infection is a serious threat to public health that affecting immunocompetent and immunocompromised individuals at different levels of severity worldwide [1]. Within the genus Candida, C. albicans is the most virulent and predominant species in oral mucosal layers, vaginal infections, and invasive bloodstream infections [2,3]. Only a few drugs, such as azoles, polyenes, pyrimidines and echinocandins, are available to treat these types of infections. Fluconazole, in particular, is used extensively in clinical practice because of its high efficacy and reduced toxicity [4]. (Source: Photodiagnosis and Photodynamic Therapy)
Source: Photodiagnosis and Photodynamic Therapy - April 4, 2018 Category: Laser Surgery Authors: Shaona Zhou, Zhiyuan Sun, Zulin Ye, Ying Wang, Leili Wang, Limei Xing, Haixia Qiu, Naiyan Huang, Yanping Luo, Yuxia Zhao, Ying Gu Source Type: research