Photodynamic inactivation assisted by localized surface plasmon resonance of silver nanoparticles: in vitro evaluation on Escherichia coli and Streptococcus mutans

Light-based therapy and diagnosis are essential non-invasive tools on medical and biomedical applications. The interaction of light with biological tissue can be prompted with the use of external agents, as photosensitizers, dyes, scatters, and fluorescent particles [1,2]. In particular, photodynamic inactivation (PDI) has been extensively used as a promising antimicrobial approach since it does not promote the selection of mutant resistant strains [3,4]. PDI explores the light-interaction with specific photosensitizers (PSs) to induce oxidative stress on microorganism, leading to cell death via different targets [5,6].

Source: Photodiagnosis and Photodynamic Therapy - April 17, 2018 Category: Laser Surgery Authors: Martha S. Ribeiro, Luciana S.A. de Melo, Sajid Farooq, Alessandra Baptista, Ilka T. Kato, Silvia C. N úñez, Renato E. de Araujo Source Type: research