Can red-light 5-aminolevulinic photodynamic therapy cure port wine stains on comb animal model?

The nevus flammeus, also named port wine stains(PWS), is congenital venous malformation and common congenital papillary telangiectasia [1,2]. Now, the pulsed dye laser (PDL) is the ‘gold standard’ for the treatment of PWS [3]. But it is mainly used in superficial PWS. For large area PWS, the curative effect is not ideal due to the defects of careless operation, easy scarring and recurring. With the development of technology, photodynamic therapy(PDT) is used successfully t o treat PWS. Compared with PDL, PDT has higher selectivity, which is especially suitable for the treatment of PWS in large area.

Source: Photodiagnosis and Photodynamic Therapy - May 5, 2018 Category: Laser Surgery Authors: Yongxian Lai, Haiyan Zhang, Minglei Wei, Jie Ji, Lei Shi, Peiru Wang, Bo Wang, Zheng Huang, Xiuli Wang Source Type: research