A clinicoetiological analysis of patients with Stevens–Johnson syndrome and toxic epidermal necrolysis treated at Sohag University Hospital, Egypt
Conclusion: SJS and TEN are uncommon diseases. Most of the cases of SJS/TEN were drug-induced. The most common offending drugs were carbamazepine, NSAIDs, and antibiotics. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - January 1, 2017 Category: Dermatology Tags: Original articles Source Type: research
Psychiatric disorders associated with some chronic dermatologic diseases among a group of Egyptian dermatology outpatient clinic attendants
Conclusion: Patients with chronic dermatologic diseases are at high risk of developing psychological problems which may continue even after improvement of skin disease. The associated psychiatric disorders can range from short episodes of depression to major depression, anxiety, obsessive–compulsive disorders, and sleep disorders and can even extend to suicidal ideation and suicidal attempts. Management of the interaction between the mind and the skin can help to improve patients’ skin conditions and eventually their quality of life. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - January 1, 2017 Category: Dermatology Tags: Original articles Source Type: research
Half-side comparison between adipose tissue stem cell-enriched fat versus standard fat injection for hand rejuvenation
Conclusion: Adipose tissue-derived stem cell-enriched fat grafting is superior in longevity to traditional autologous fat transfer for hand rejuvenation. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - January 1, 2017 Category: Dermatology Tags: Original articles Source Type: research
Hair loss among a group of Egyptian children: a clinical and dermoscopic study
Conclusion: Hair loss is a common problem among Egyptian children, wherein tinea capitis showed the highest percentage. The routine use of dermoscopy in scalp and hair disorders improves diagnostic capability beyond simple clinical inspection, thus aiding in accurate diagnosis and better management of alopecia. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - January 1, 2017 Category: Dermatology Tags: Original articles Source Type: research
Emerging treatments for vitiligo: gaining insight from pathogenesis
Vitiligo is an under-recognized, devastating autoimmune skin disease with limited treatment options. There are currently no Food and Drug Administration-approved treatments for vitiligo that reverse the course of disease, and standard off-label treatments are limited in efficacy. Furthermore, the mechanisms of current treatments are largely unknown, although general, nontargeted immunosuppression is most likely. Indeed, lack of significant success in treatment is often the reason for a pessimistic outlook by both the treating physician and the patient, highlighting the need for better treatment options. Over the past three...
Source: Journal of the Egyptian Women’s Dermatologic Society - January 1, 2017 Category: Dermatology Tags: Review article Source Type: research
Comparative study between microneedling alone and microneedling combined with platelet-rich plasma in the treatment of striae distensae using clinical and histopathological assessment
Conclusion: Microneedling is safe and more effective when used with PRP for the treatment of striae distensae. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2016 Category: Dermatology Tags: Original articles Source Type: research
Serum thymic stromal lymphopoietin in pediatric atopic patients and its relation to the development of the atopic march
Conclusion: Serum TSLP was not found to be a specific marker of AD or atopic status in general in pediatric patients. It cannot be used as a marker of disease activity or severity, and also cannot be used as a predictive marker for the development of the atopic march. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2016 Category: Dermatology Tags: Original articles Source Type: research
Comparison between serum level of superoxide dismutase, malondialdehyde, and DNA damage in acne vulgaris and vitiligo patients
Background: Free radical-mediated reactions and oxidative stress have been implicated in the pathogenesis of acne, but their role in eliciting this response and contributing to disease progress remains unexplored.
Objective: To evaluate the extent of oxidative stress and DNA damage in patients with acne vulgaris in comparison with patients with vitiligo, a disease with a well-known and documented role of oxidative stress in its pathogenesis.
Patients and methods: Serum from 15 patients with acne vulgaris, 15 patients with vitiligo, and 15 age-matched and sex-matched controls were evaluated for serum levels of superoxide ...
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2016 Category: Dermatology Tags: Original articles Source Type: research
Autologous adipose-derived adult stem cells injection versus platelet-rich plasma injection in the treatment of rolling postacne scars
Conclusion: Both AT-ASCs and PRP are safe, effective, and tolerable methods for the treatment of rolling acne scars without serious complications. PRP was found to be superior to AT-ASCs. Optimization of the results may be achieved by combining AT-ASCs and PRP in the same session. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2016 Category: Dermatology Tags: Original articles Source Type: research
Evaluation of topical potassium hydroxide in the treatment of nongenital warts
Conclusion: Topical KOH solution is a promising treatment modality for warts. It seems to be an easy, effective, painless, inexpensive, and safe treatment option. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2016 Category: Dermatology Tags: Original articles Source Type: research
Intralesional injection of purified protein derivatives versus zinc sulfate 2% in recalcitrant palmar and/or plantar warts
Conclusion: IL immunotherapy with tuberculin PPD was more effective than zinc sulfate 2% in the treatment of cutaneous warts. It is a simple, effective, safe procedure, with tolerable pain, and it may represent an alternative treatment for multiple resistant palmar and/or plantar warts. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2016 Category: Dermatology Tags: Original articles Source Type: research
Reliability and validity of the Arabic version of the Psoriasis Disability Index questionnaire
Conclusion: The Arabic version of the PDI questionnaire was found to be a reliable and valid measure for evaluating the quality of life for Egyptian patients with psoriasis. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2016 Category: Dermatology Tags: Original articles Source Type: research
Is there an association between TNFR2 M196R polymorphism and acne vulgaris in Egyptian patients?
Conclusion: TNFR2 M196R polymorphism was not a risk factor for acne development or severity in this sample from the Egyptian population. However; it may have an influence on its severity. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2016 Category: Dermatology Tags: Original articles Source Type: research
Gene expression of FOXP3 and TGF-β1 in the blood of patients with mycosis fungoides, a hospital-based case–control study
Background: Regulatory T cells (Tregs) are FOXP3+ subpopulation of CD4+ T cells with transforming growth factor (TGF)-β1-mediated immunosuppressive effects. They play a role in the etiopathogenesis of various malignancies including cutaneous T-cell lymphomas.
Objectives: To study the gene expression of FOXP3 and TGF-β1 in the blood of mycosis fungoides (MF) patients compared with controls.
Patients and methods: Venous blood of 5 ml was taken from 25 MF patients and 25 healthy volunteers. Samples were subjected to real-time PCR for the measurement of FOXP3 and TGF-β1 mRNA expression.
Results: Although FOXP3 mRNA level...
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2016 Category: Dermatology Tags: Original articles Source Type: research
The angiotensin-converting enzyme insertion/deletion polymorphism of vitiligo in a population in upper Egypt: a hospital-based study
Background: Vitiligo is an acquired depigmentary disorder resulting from the loss of functional melanocytes and melanin from the skin. The causes of the nonfunctional effects on melanocytes remain unclear. There is considerable evidence that genes play a significant role in the pathogenesis of vitiligo. A few genes have been reported to contribute toward susceptibility to vitiligo. One of these is the angiotensin-converting enzyme (ACE) gene.
Objective: To investigate the distribution of the ACE genotype in vitiligo patients in upper Egypt to examine whether the insertion (I) and deletion (D) of the ACE polymorphism confe...
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2016 Category: Dermatology Tags: Original articles Source Type: research
