Serum and tissue levels of total antioxidant capacity in nonsegmental vitiligo
Conclusion
We proved a defective antioxidant system in vitiligo in the form of abnormally low serum and tissue levels of TAC. These findings provide further support for a free radical-mediated damage, especially on the tissue level, as an initial pathogenic event in destruction of melanocytes in vitiligo. Therefore, these findings support the role of antioxidant therapy in vitiligo. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - January 1, 2018 Category: Dermatology Tags: Original articles Source Type: research
Is vitamin D a participant in narrow-band ultraviolet B-induced pigmentation in patients with vitiligo?
Conclusion
Low vitamin D level may play an active role in vitiligo development. Furthermore, vitamin D may participate partially in photo-induced melanogenesis. Therefore, the mechanism of NBUVB-induced pigmentation in vitiligo needs to be clarified. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - January 1, 2018 Category: Dermatology Tags: Original articles Source Type: research
Comparison of matrix metalloproteinase-1 expression in tumor-associated and nontumor-associated skin in patients with basal cell carcinoma
This study included 24 BCC patients, who also represented the controls by taking punch biopsies from normal skin on the dorsa of their hands (as sun-exposed areas). Immunohistochemical assessment of MMP-1 in lesional skin biopsy and control biopsies was carried out.
Results
MMP-1 expression in peritumoral area of BCC was significantly higher than the tumoral area, safety margin, and control (P60 years) showed greater MMP-1 expression compared to their counterparts in younger age group (P (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - January 1, 2018 Category: Dermatology Tags: Original articles Source Type: research
TOX as a diagnostic and prognostic marker for mycosis fungoides
Conclusion
TOX may participate in the pathogenesis of MF. It could be considered a diagnostic and prognostic marker for MF. TOX expression correlates with increased risks of disease progression and a poor prognosis. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - January 1, 2018 Category: Dermatology Tags: Original articles Source Type: research
Expression of soluble and membrane-bound programmed death protein 1 in psoriasis vulgaris patients: a case-controlled study
The objective of this study was to assess both soluble programmed cell death-1 (sPD1) and membrane-bound PD1 levels in psoriatic patients, and to correlate them with disease severity.
Patients and methods
Twenty-one psoriatic patients and 20 age-matched and sex-matched controls were included. Full clinical examination was done and tissue and blood levels of PD1 were measured by enzyme-linked immunosorbent assay.
Results
Levels of sPD1 were significantly lower in patients than in controls (P (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - January 1, 2018 Category: Dermatology Tags: Original articles Source Type: research
Acute and chronic radiodermatitis: clinical signs, pathophysiology, risk factors and management options
Radiodermatitis (RD) is a cutaneous reaction that occurs as a side-effect of radiotherapy during cancer treatment or sometimes after interventional radiology. There are two forms of RD depending on the time the skin reaction occurs. Acute skin reactions develop a few hours to weeks after the first exposure to radiation, whereas chronic RD can develop months, years or even decades after radiation. Both acute and chronic RD can substantially affect the patients’ quality of life and cosmetic outcome. Therefore, a proper prevention and treatment strategy for RD is needed. However, the scientific evidence for effective manage...
Source: Journal of the Egyptian Women’s Dermatologic Society - January 1, 2018 Category: Dermatology Tags: Review article Source Type: research
Obituary
No abstract available (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - January 1, 2018 Category: Dermatology Tags: Obituary Source Type: research
What is your diagnosis?
No abstract available (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2017 Category: Dermatology Tags: Quiz Source Type: research
Case report: lymphedema vulva secondary to hidradenitis suppurativa
Lymphedema of vulva is a rare entity characterized by chronic and progressive engorgement of tissues. It is a diagnostic challenge which is frequently untreated or treated at a late stage. The condition is highly debilitating because of the physical difficulty and mental agony associated with it. There are various underlying causes of lymphedema vulva but the association of lymphedema vulva and hidradenitis suppurativa (HS) is not well recognized. We would like to share the case report of a 35 year old female patient who developed vulval lymphoedema as a complication of longstanding HS. (Source: Journal of the Egyptian Wom...
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2017 Category: Dermatology Tags: Case report Source Type: research
Serum vitamin D level in Egyptian children with atopic dermatitis and efficacy of vitamin D supplementation
Conclusion
Serum levels of 25(OH)D were significantly lower in patients than the controls and vitamin D deficiency is related to the severity of AD, suggesting a therapeutic benefit from oral vitamin D supplementation in improvement of disease severity. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2017 Category: Dermatology Tags: Original articles Source Type: research
Evaluation of efficacy of an intralesional injection of Candida antigen in the treatment of molluscum contagiosum
Background
Different treatment modalities are available for molluscum contagiosum (MC). However, these modalities are often traumatic for children and associated with frequent recurrence.
Objective
To evaluate the efficacy and safety of an intralesional injection of Candida antigen in the treatment of MC.
Patients and methods
Sixteen patients with multiple MC lesions were subjected to intralesional immunotherapy with 0.3 ml of Candida albicans antigen after previous intradermal skin testing for existing immunity. Also, 16 MC patients were subjected to an intralesional neutral saline injection as a control group. Al...
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2017 Category: Dermatology Tags: Original articles Source Type: research
Endocan level in serum and lesional skin of psoriasis vulgaris patients
Background
It is proven that severe psoriasis might be associated with an increased mortality rate because of a higher prevalence of metabolic syndrome and cardiovascular disorders. Endocan is a human cell-specific molecule that is expressed by the vascular endothelium. Endothelial dysfunction is widely accepted as being involved in the development of psoriasis, as well as atherosclerosis.
Objective
To investigate serum and tissue levels of endocan in psoriatic patients versus nonpsoriatic controls, as it may have a role in the pathogenesis of psoriasis, and to correlate these levels to psoriasis area severity index s...
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2017 Category: Dermatology Tags: Original articles Source Type: research
Levels of osteopontin in plasma and tissue in relation to metabolic status in patients with lichen planus
Conclusion
The presence of LP in patients was associated strongly with MetS parameters, most probably because of long-standing inflammation. OPN may be a critical regulator of chronic inflammation in patients with LP and may explain its association with components of the MetS such as diabetes mellitus and dyslipidemia. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2017 Category: Dermatology Tags: Original articles Source Type: research
Relationship between lipase enzyme and antimicrobial susceptibility of Staphylococcus aureus-positive and Staphylococcus epidermidis-positive isolates from acne vulgaris
Conclusion
Although, Staphylococci spp. isolated from acne lesions showed lipase activity and high prevalent rates of antimicrobial resistance, the association between lipase enzyme and antibiotic susceptibility was statistically insignificant. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2017 Category: Dermatology Tags: Original articles Source Type: research
Increased density of CD1a+ Langerhans cells and CD86+ cells in perilesional and lesional psoriatic skin: an immunohistochemical study
Conclusion
The prominent density of CD1a+ and CD86+ DC in the perilesional skin compared with the lesional psoriatic skin suggests the pathogenetic role of these cells in the initiation of plaque psoriasis. The simultaneous presence and close localization of CD1a+ and CD86+ cells in the psoriatic dermal and epidermal compartments suggests that their interaction potentially contributes to the development of psoriasis. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2017 Category: Dermatology Tags: Original articles Source Type: research
