Comparison of matrix metalloproteinase-1 expression in tumor-associated and nontumor-associated skin in patients with basal cell carcinoma

This study included 24 BCC patients, who also represented the controls by taking punch biopsies from normal skin on the dorsa of their hands (as sun-exposed areas). Immunohistochemical assessment of MMP-1 in lesional skin biopsy and control biopsies was carried out. Results MMP-1 expression in peritumoral area of BCC was significantly higher than the tumoral area, safety margin, and control (P60 years) showed greater MMP-1 expression compared to their counterparts in younger age group (P
Source: Journal of the Egyptian Women’s Dermatologic Society - Category: Dermatology Tags: Original articles Source Type: research