Bimatoprost: a potential therapeutic tool for alopecia areata of the scalp: Erratum
No abstract available (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2014 Category: Dermatology Tags: Erratum Source Type: research

Dermoscopy: an easy, noninvasive tool for distinguishing mycosis fungoides from other inflammatory mimics
BackgroundMycosis fungoides (MF), the most common type of cutaneous T-cell lymphoma, can sometimes be indistinguishable from plaque psoriasis (PP), chronic dermatitis, and lichen planus (LP). ObjectiveThe aim of the study was to assess the value of dermoscopy as a quick screening tool to distinguish MF from PP, chronic dermatitis, and LP. Patients and methodsThe dermoscopic profiles of 21 MF, 20 PP, 20 chronic dermatitis, and 20 LP patients were included in this study. ResultsAll 20 PP patients (100%) showed homogenous red globules on a red background with white scales. All 20 LP patients (100%) showed whitish projections....
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2014 Category: Dermatology Tags: Original articles Source Type: research

Expression of Langerhans cells, dermal dendritic cells, and plasmacytoid dendritic cells in early stage mycosis fungoides: a case–control study
ConclusionA possible role is played by LCs, DDCs, and pDCs in the pathogenesis of MF. However, whether the DCs appeared in reaction to tumor cells to antagonize their progression or to be a source for chronic antigenic stimulation resulting in the immune escape of tumor cells and perpetuation of the disease needs more clarification. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2014 Category: Dermatology Tags: Original articles Source Type: research

Apoptotic markers in spongiotic dermatitis
BackgroundKeratinocyte (KC) apoptosis is believed to play an important role in the pathogenesis of spongiotic dermatitis, in particular for the formation of spongiosis. ObjectiveTo investigate changes in the expression level of the apoptosis regulatory proteins cleaved caspase-3, Fas, Bcl-2, nuclear factor κB (NF-κB) and p53 in skin samples of patients with spongiotic dermatitis. Patients and methodsThe present study included a total of 50 patients with spongiotic dermatitis and 10 healthy controls. Patients were classified into five groups (10 patients each): group A, atopic dermatitis; group B, allergic contact dermati...
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2014 Category: Dermatology Tags: Original articles Source Type: research

Evaluation of bullous pemphigoid 180 ELISA in the diagnosis of bullous pemphigoid patients
ConclusionBP180 ELISA can be useful in the diagnosis and follow-up of some BP patients; however, DIF remains the standard method for diagnosis of this disease. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2014 Category: Dermatology Tags: Original articles Source Type: research

Clinical and dermoscopic evaluation of patients with periorbital darkening
ConclusionDermoscopic evaluation of periorbital darkening/melanosis appears valuable, particularly in the determination of the degree and pattern of pigmentation as well as the extent of vascular involvement, which in turn would reflect on the choice of therapy. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2014 Category: Dermatology Tags: Original articles Source Type: research

Evaluation of 25-hydroxy vitamin D and specific immunoglobulin E to Staphylococcus aureus in patients with atopic dermatitis and their correlation with the disease severity
ConclusionVitamin D may be insufficient or deficient in a subset of AD children, especially those with moderate and severe disease; these patients were sensitive to S. aureus. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2014 Category: Dermatology Tags: Original articles Source Type: research

Pattern of skin diseases among preschool and primary school-aged children in Dermatology Damietta Hospital
ConclusionThe present study sheds light on the most frequent dermatoses encountered in Damietta Hospital, and provides the basis for better health services in this hospital. Infectious skin diseases represent a large proportion of the cases analyzed. Community-based studies need to be carried out to confirm and explore our findings to determine the magnitude and pattern of different types of dermatoses in Damietta affecting that age group, which could be a basis for future health plans. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2014 Category: Dermatology Tags: Original articles Source Type: research

Photodynamic therapy using 5-aminolevulinic acid and intense pulsed light against intense pulsed light alone in the treatment of acne vulgaris
ConclusionAnalysis of the results revealed that both ALA-PDT with IPL as a light source and IPL alone are efficient and safe treatment modalities for acne vulgaris with superiority of ALA-PDT in reduction of inflammatory lesions. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2014 Category: Dermatology Tags: Original articles Source Type: research

Hyperpigmented and flesh-colored skin tags: what is the difference? A histopathological and immunohistochemical study
ConclusionWe attribute the change in STs color to melanocyte–mast cell interaction as well as to the degree of acanthosis/papillomatosis. Further studies are still required for a deeper understanding of reasons behind such change and for the clinical implications of such findings. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2014 Category: Dermatology Tags: Original articles Source Type: research

Safety and efficacy of modified Jessner’s solution versus 70% glycolic acid for the treatment of melasma in different skin types: a split-face study
BackgroundThe treatment of melasma has been challenging; numerous approaches have been used with variable results. Chemical peeling is an established technique for the treatment of pigmentary imperfections. ObjectiveThe aim of the study was to compare the efficacy and safety of glycolic acid (GA) 70% and a modified Jessner’s solution in the treatment of melasma in different skin types among a sample of Egyptian women. Patients and methodsThirty women with a clinical diagnosis of melasma were selected. Modified Jessner’s solution and GA 70% were applied on a split-face basis at a 2-week interval for a maximum of eight s...
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2014 Category: Dermatology Tags: Original articles Source Type: research

Vitiligo: a review of the pathogenesis
This article explains the most relevant findings for the five main theories that have been proposed as the underlying cause for vitiligo. It was concluded that while etiology of vitiligo is not fully understood, great strides have been made in gaining a better picture of the various causes of vitiligo. There is substantial amount of evidence supporting the genetic, neural, autoimmune, biochemical, and melanocytorrhagy theories of vitiligo which provides a solid foundation for future research. (Source: Journal of the Egyptian Women’s Dermatologic Society)
Source: Journal of the Egyptian Women’s Dermatologic Society - September 1, 2014 Category: Dermatology Tags: Review article Source Type: research