Melatonin protects oocyte quality from Bisphenol A ‐induced deterioration in the mouse
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - February 7, 2017 Category: Research Authors: Mianqun Zhang, Xiaoxin Dai, Yajuan Lu, Yilong Miao, Changyin Zhou, Zhaokang Cui, Honglin Liu, Bo Xiong Tags: Original Article Source Type: research

Pre ‐ischemia melatonin treatment alleviated acute neuronal injury after ischemic stroke by inhibiting ER stress‐dependent autophagy via PERK and IRE1 signalings
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - February 7, 2017 Category: Research Authors: Dayun Feng, Bao Wang, Lei Wang, Neeta Abraham, Kai Tao, Lu Huang, Wei Shi, Yushu Dong, Yan Qu Tags: Original Article Source Type: research

Melatonin restores hippocampal neural precursor proliferation and prevents cognitive deficits induced by jet lag simulation in adult mice
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - February 7, 2017 Category: Research Authors: Deetje Iggena, York Winter, Barbara Steiner Tags: Original Article Source Type: research

Melatonin prevents mitochondrial dysfunction and promotes neuroprotection by inducing autophagy during oxaliplatin ‐evoked peripheral neuropathy
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - January 23, 2017 Category: Research Authors: Aparna Areti, Prashanth Komirishetty, Manasaveena Akuthota, Rayaz A Malik, Ashutosh Kumar Tags: Original Article Source Type: research

Long ‐term melatonin treatment delays ovarian aging
This study examined whether long‐term melatonin treatment would delay ovarian aging in mice. Female ICR mice (10 weeks old) were given melatonin‐containing water (100 μg/mL; melatonin) or water only until 43 weeks of age. Their oocytes were recovered from the oviduct, and in vitro fertilization was performed. The ovaries were used for a histological analysis of the number of follicles. The mRNA expression of the aging‐related sirtuin genes (SIRT1, SIRT3) and the autophagy‐related gene (LC3) and the telomere length of the ovarian chromosomes were analyzed. Transcriptome changes in the ovaries were also character...
Source: Journal of Pineal Research - January 22, 2017 Category: Research Authors: Hiroshi Tamura, Mai Kawamoto, Shun Sato, Isao Tamura, Ryo Maekawa, Toshiaki Taketani, Hiromi Aasada, Eiichi Takaki, Akira Nakai, Russel J. Reiter, Norihiro Sugino Tags: ORIGINAL ARTICLE Source Type: research

Melatonin alleviates cadmium ‐induced liver injury by inhibiting the TXNIP‐NLRP3 inflammasome
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - January 17, 2017 Category: Research Authors: Zhengwang Cao, Yiliang Fang, Yonghui Lu, Dunxian Tan, Changhong Du, Yuming Li, Qinlong Ma, Junmei Yu, Mengyan Chen, Chao Zhou, Liping Pei, Lei Zhang, Haiying Ran, Mindi He, Zhengping Yu, Zhou Zhou Tags: Original Article Source Type: research

Potentiation of biological effects of mesenchymal stem cells in ischemic conditions by melatonin via upregulation of cellular prion protein expression
In conclusion, melatonin‐treated MSCs could provide a therapeutic strategy for vessel regeneration in ischemic disease, and the targeting of PrPC levels may prove instrumental for MSC‐based therapies. This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - January 16, 2017 Category: Research Authors: Jun Hee Lee, Yong ‐Seok Han, Sang Hun Lee Tags: Original Article Source Type: research

Melatonin ameliorates alcohol ‐induced bile acid synthesis by enhancing miR‐497 expression
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - January 16, 2017 Category: Research Authors: Yong Deuk Kim, Seung ‐Lark Hwang, Eun‐Joo Lee, Hyeong‐Mi Kim, Myung‐Jin Chung, Ahmed K. Elfadl, Sung‐Eun Lee, Balachandar Nedumaran, Robert A. Harris, Kyu‐Shik Jeong Tags: Original Article Source Type: research

HsfA1a upregulates melatonin biosynthesis to confer cadmium tolerance in tomato plants
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - January 16, 2017 Category: Research Authors: Shu ‐Yu Cai, Yun Zhang, You‐Ping Xu, Zhen‐Yu Qi, Meng‐Qi Li, Golam Jalal Ahammed, Xiao‐Jian Xia, Kai Shi, Yan‐Hong Zhou, Russel J. Reiter, Jing‐Quan Yu, Jie Zhou Tags: Original Article Source Type: research

Melatonin prevents obesity through modulation of gut microbiota in mice
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - December 31, 2016 Category: Research Authors: Pengfei Xu, Jialin Wang, Fan Hong, Sheng Wang, Xi Jin, Tingting Xue, Li Jia, Yonggong Zhai Tags: Original Article Source Type: research

Melatonin promotes sorafenib induced apoptosis through synergistic activation of JNK/c ‐jun pathway in human hepatocellular carcinoma
This study demonstrates that melatonin in combination with sorafenib synergistically inhibits proliferation and induces apoptosis in human HCC cells; therefore, supplementation of sorafenib with melatonin may serve as a potential therapeutic choice for advanced HCC. This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - December 31, 2016 Category: Research Authors: Shibo Lin, Katrin Hoffmann, Chao Gao, Marius Petrulionis, Ingrid Herr, Peter Schemmer Tags: Original Article Source Type: research

Melatonin signaling in T cells: Functions and applications
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - December 31, 2016 Category: Research Authors: Wenkai Ren, Gang Liu, Shuai Chen, Jie Yin, Jing Wang, Bie Tan, Guoyao Wu, Fuller W. Bazer, Yuanyi Peng, Tiejun Li, Russel J. Reiter, Yulong Yin Tags: Review Source Type: research

Overexpression of rice serotonin N ‐acetyltransferase1 in transgenic rice plants confers resistance to cadmium and senescence and increases grain yield
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - December 31, 2016 Category: Research Authors: Kyungjin Lee, Kyoungwhan Back Tags: Original Article Source Type: research

Melatonin and sirtuins: a ‘not‐so unexpected’ relationship
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - December 31, 2016 Category: Research Authors: Juan C Mayo, Rosa M. Sainz, Pedro Gonz ález Menéndez, Vanesa Cepas, Dun‐Xian Tan, Russel J. Reiter Tags: Review Source Type: research

Human transporters, PEPT1/2, facilitate melatonin transportation into mitochondria of cancer cells: an implication of the therapeutic potential
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - December 31, 2016 Category: Research Authors: Xiaokui Huo, Chao Wang, Zhenlong Yu, Yulin Peng, Shumei Wang, Shengnan Feng, Shouji Zhang, Xiangge Tian, Chengpeng Sun, Kexin Liu, Sa Deng, Xiaochi Ma Tags: Original Article Source Type: research