Melatonin promotes sorafenib induced apoptosis through synergistic activation of JNK/c ‐jun pathway in human hepatocellular carcinoma

This study demonstrates that melatonin in combination with sorafenib synergistically inhibits proliferation and induces apoptosis in human HCC cells; therefore, supplementation of sorafenib with melatonin may serve as a potential therapeutic choice for advanced HCC. This article is protected by copyright. All rights reserved.
Source: Journal of Pineal Research - Category: Research Authors: Tags: Original Article Source Type: research