Melatonin promotes sorafenib induced apoptosis through synergistic activation of JNK/c ‐jun pathway in human hepatocellular carcinoma
This study demonstrates that melatonin in combination with sorafenib synergistically inhibits proliferation and induces apoptosis in human HCC cells; therefore, supplementation of sorafenib with melatonin may serve as a potential therapeutic choice for advanced HCC.
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Source: Journal of Pineal Research - Category: Research Authors: Shibo Lin, Katrin Hoffmann, Chao Gao, Marius Petrulionis, Ingrid Herr, Peter Schemmer Tags: Original Article Source Type: research
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