Identification, transcriptional and functional analysis of heat ‐shock protein 90s in banana (Musa acuminata L.) highlight their novel role in melatonin‐mediated plant response to Fusarium wilt
In this study, nine 90 kDa heat‐shock proteins (HSP90s) were genomewide identified. Moreover, the expression profile of them in different organs, developmental stages, and in response to abiotic and fungal pathogen Foc were systematically analyzed. Notably, we found that the transcripts of 9 MaHSP90s were commonly regulated by melatonin (N‐acetyl‐5‐methoxytryptamine) and Foc infection. Further studies showed that exogenous application of melatonin improved banana resistance to Fusarium wilt, but the effect was lost when cotreated with HSP90 inhibitor (geldanamycin, GDA). Moreover, melatonin and GDA had opposite e...
Source: Journal of Pineal Research - October 11, 2016 Category: Research Authors: Yunxie Wei, Wei Hu, Qiannan Wang, Hongqiu Zeng, Xiaolin Li, Yu Yan, Russel J. Reiter, Chaozu He, Haitao Shi Tags: Original Article Source Type: research
Cancer metastasis: mechanisms of inhibition by melatonin
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - October 4, 2016 Category: Research Authors: Shih ‐Chi Su, Ming‐Ju Hsieh, Wei‐En Yang, Wen‐Hung Chung, Russel J. Reiter, Shun‐Fa Yang Tags: Review Source Type: research
Melatonin and the pathologies of weakened or dysregulated circadian oscillators
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - September 30, 2016 Category: Research Authors: R üdiger Hardeland Tags: Review Source Type: research
Melatonin rescues cardiac thioredoxin system during ischemia ‐reperfusion injury in acute hyperglycemic state by restoring Notch1/Hes1/Akt signaling in a membrane receptor‐dependent manner
This study aimed to investigate the protective effect of melatonin against myocardial ischemia‐reperfusion (MI/R) injury in acute hyperglycemic state with a focus on Notch1/Hes1/Akt signaling and intracellular thioredoxin (Trx) system. Sprague‐Dawley rats were subjected to MI/R surgery and high glucose (HG, 500 g/L) infusion (4 ml/kg/h) to induce temporary hyperglycemia. Rats were treated with or without melatonin (10 mg/kg/d) during the operation. Furthermore, HG (33mM) incubated H9c2 cardiomyoblasts were treated in the presence or absence of Luzindole (a competitive melatonin receptor antagonist), DAPT (a γ‐Secret...
Source: Journal of Pineal Research - September 30, 2016 Category: Research Authors: Liming Yu, Chongxi Fan, Zhi Li, Jian Zhang, Xiaodong Xue, Yinli Xu, Guolong Zhao, Yang Yang, Huishan Wang Tags: Original Article Source Type: research
Melatonin attenuates post ‐myocardial infarction injury via increasing Tom70 expression
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - September 30, 2016 Category: Research Authors: Hai ‐Feng Pei, Juan‐Ni Hou, Fei‐Peng Wei, Qiang Xue, Fan Zhang, Cheng‐Fei Peng, Yi Yang, Yue Tian, Juan Feng, Jin Du, Lei He, Xiu‐Chuan Li, Er‐He Gao, De Li, Yong‐Jian Yang Tags: Original Article Source Type: research
Melatonin prevents deregulation of the sphingosine kinase/sphingosine 1 ‐phosphate signaling pathway in a mouse model of diethylnitrosamine‐induced hepatocellular carcinoma
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - September 30, 2016 Category: Research Authors: Diana I S ánchez, Bárbara González‐Fernández, Beatriz San‐Miguel, Juan Ortiz de Urbina, Irene Crespo, Javier González‐Gallego, María J Tuñón Tags: Original Article Source Type: research
Melatonin alleviates post ‐infarction cardiac remodeling and dysfunction by inhibiting Mst1
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - September 30, 2016 Category: Research Authors: Jianqiang Hu, Lei Zhang, Yang Yang, Yanjie Guo, Yanhong Fan, Mingming Zhang, Wanrong Man, Erhe Gao, Wei Hu, Russel J. Reiter, Haichang Wang, Dongdong Sun Tags: Original Article Source Type: research
Identification, transcriptional and functional analysis of heat shock protein 90s in banana (Musa acuminata L.) highlight their novel role in melatonin ‐mediated plant response to Fusarium wilt
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - September 15, 2016 Category: Research Authors: Yunxie Wei, Wei Hu, Qiannan Wang, Hongqiu Zeng, Xiaolin Li, Yu Yan, Russel J. Reiter, Chaozu He, Haitao Shi Tags: Original Article Source Type: research
Issue Information
(Source: Journal of Pineal Research)
Source: Journal of Pineal Research - September 8, 2016 Category: Research Tags: Issue Information Source Type: research
Melatonin biosynthesis in plants: multiple pathways catalyze tryptophan to melatonin in the cytoplasm or chloroplasts
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - September 6, 2016 Category: Research Authors: Kyoungwhan Back, Dun ‐Xian Tan, Russel J. Reiter Tags: Review Source Type: research
Melatonin suppresses TPA ‐induced metastasis by downregulating matrix metalloproteinase‐9 expression through JNK/SP‐1 signaling in nasopharyngeal carcinoma
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - September 6, 2016 Category: Research Authors: Hsin ‐Yu Ho, Chiao‐Wen Lin, Ming‐Hsien Chien, Russel J. Reiter, Shih‐Chi Su, Yi‐Hsien Hsieh, Shun‐Fa Yang Tags: Original Article Source Type: research
Melatonin promotes cardiomyogenesis of embryonic stem cells via inhibition of HIF ‐1alpha stabilization
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - August 31, 2016 Category: Research Authors: Jana Kudov á, Ondřej Vašíček, Milan Číž, Lukáš Kubala Tags: Original Article Source Type: research
Apoptosis signaling pathways in osteoarthritis and possible protective role of melatonin
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - August 24, 2016 Category: Research Authors: Azam Hosseinzadeh, Seyed Kamran Kamrava, Mohammad Taghi Joghataei, Radbod Darabi, Ali Shakeri ‐Zadeh, Mansour Shahriari, Russel J. Reiter, Habib Ghaznavi, Saeed Mehrzadi Tags: Review Source Type: research
Melatonin modulates neonatal brain inflammation through endoplasmic reticulum stress, autophagy, and miR ‐34a/silent information regulator 1 pathway
Abstract
Maternal infection/inflammation represents one of the most important factors involved in the etiology of brain injury in newborns. We investigated the modulating effect of prenatal melatonin on the neonatal brain inflammation process resulting from maternal intraperitoneal (i.p.) lipopolysaccharide (LPS) injections. LPS (300 μg/kg) was administered to pregnant rats at gestational days 19 and 20. Melatonin (5 mg/kg) was administered i.p. at the same time as LPS. Melatonin counteracted the LPS sensitization to a second ibotenate‐induced excitotoxic insult performed on postnatal day (PND) 4. As melatonin succeed...
Source: Journal of Pineal Research - August 12, 2016 Category: Research Authors: Silvia Carloni, G éraldine Favrais, Elie Saliba, Maria Cristina Albertini, Sylvie Chalon, Mariangela Longini, Pierre Gressens, Giuseppe Buonocore, Walter Balduini Tags: Original Article Source Type: research
Molecular cloning of melatonin 3 ‐hydroxylase and its production of cyclic 3‐hydroxymelatonin in rice (Oryza sativa)
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - August 8, 2016 Category: Research Authors: Kyungjin Lee, Zbigniew Czarnocki, Russel J. Reiter, Kyoungwhan Back Tags: Original Article Source Type: research
