Plant mitochondria synthesize melatonin and enhance the tolerance of plants to drought stress
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - May 1, 2017 Category: Research Authors: Lin Wang, Chao Feng, Xiaodong Zheng, Yan Guo, Fangfang Zhou, Dongqian Shan, Xuan Liu, Jin Kong Tags: Original Article Source Type: research
Melatonin reduces endoplasmic reticulum stress and corneal dystrophy ‐associated TGFBIp through activation of endoplasmic reticulum‐associated protein degradation
In conclusion, this study provides new insights into the mechanisms by which melatonin confers its protective actions during ER stress. The results also indicate that melatonin might have potential as a therapeutic agent for ER stress‐related diseases including GCD2.
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - May 1, 2017 Category: Research Authors: Seung ‐il Choi, Eunhee Lee, Begum Akuzum, Jang Bin Jeong, Yong‐Sun Maeng, Tae‐im Kim, Eung Kweon Kim Tags: Original Article Source Type: research
Melatonin influences the sonic hedgehog signaling pathway in porcine cumulus oocyte complexes
In conclusion, our results suggest that Shh signaling mediates effects of melatonin to improve porcine cumulus expansion and subsequent embryo development.
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - May 1, 2017 Category: Research Authors: Sanghoon Lee, Jun ‐Xue Jin, Anukul Taweechaipaisankul, Geon A Kim, Curie Ahn, Byeong Chun Lee Tags: Original Article Source Type: research
Melatonin protects bone marrow mesenchymal stem cells against iron overload ‐induced osteogenic differentiation dysfunction and senescence
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - May 1, 2017 Category: Research Authors: Fan Yang, Lei Yang, Yuan Li, Gege Yan, Chao Feng, Tianyi Liu, Rui Gong, Ye Yuan, Ning Wang, Elina Idiiatullina, Timur Bikkuzin, Valentin Pavlov, Yang Li, Chaorun Dong, Dawei Wang, Yang Cao, Zhenbo Han, Lai Zhang, Qi Huang, Fengzhi Ding, Zhengang Bi, Benzh Tags: Original Article Source Type: research
Melatonin protects against diabetic cardiomyopathy through Mst1/Sirt3 signaling
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - May 1, 2017 Category: Research Authors: Mingming Zhang, Jie Lin, Shanjie Wang, Zheng Cheng, Jianqiang Hu, Tingting Wang, Wanrong Man, Tao Yin, Wenyi Guo, Erhe Gao, Russel J. Reiter, Haichang Wang, Dongdong Sun Tags: Original Article Source Type: research
Melatonin administration to wild ‐type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis
Abstract
The NLRP3 inflammasome is involved in the innate immune response during inflammation. Moreover, melatonin blunts the NF‐κB/NLRP3 connection during sepsis. Thus, we compared the roles of the NLRP3 inflammasome and/or melatonin treatment in the septic response of wild‐type and NLRP3−/− mice. Mouse myocardial tissue was used for this purpose. The nuclear turnover of NF‐κB was enhanced during sepsis, with an increase in TNFα, iNOS, and pro‐IL‐1β. The lack of inflammasome in NLRP3−/− mice significantly reduced that response and blunted IL‐1β maturation due to the lack of caspase‐1. Clock and ...
Source: Journal of Pineal Research - April 29, 2017 Category: Research Authors: Ibtissem Rahim, Bahia Djerdjouri, Ramy K. Sayed, Marisol Fern ández‐Ortiz, Beatriz Fernández‐Gil, Agustín Hidalgo‐Gutiérrez, Luis C. López, Germaine Escames, Russel J. Reiter, Darío Acuña‐Castroviejo Tags: ORIGINAL ARTICLE Source Type: research
Melatonin: a pleiotropic molecule that modulates DNA damage response and repair pathways
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - April 25, 2017 Category: Research Authors: Maryam Majidinia, Alireza Sadeghpour, Saeed Mehrzadi, Russel J. Reiter, Nasrin Khatami, Bahman Yousefi Tags: Review Source Type: research
Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - April 19, 2017 Category: Research Authors: Miguel Mendivil ‐Perez, Viviana Soto‐Mercado, Ana Guerra‐Librero, Beatriz I Fernandez‐Gil, Javier Florido, Ying‐Qiang Shen, Miguel A Tejada, Vivian Capilla‐Gonzalez, Iryna Rusanova, José M Garcia‐Verdugo, Darío Acuña‐Castroviejo, Luis C Tags: Original Article Source Type: research
Melatonin reverses H2O2 ‐induced senescence in SH‐SY5Y cells by enhancing autophagy via sirtuin 1 deacetylation of the RelA/p65 subunit of NF‐κB
This study focuses on the effect of melatonin on autophagy via the deacetylation activity of SIRT1 on RelA/p65, a subunit of NF‐ĸB, to determine whether melatonin can attenuate the aging condition. SH‐SY5Y cells were treated with H2O2 to induce the senescent state. These results demonstrated that melatonin reduced a number of beta‐galactosidase (SA‐βgal)‐positive cells, a senescent marker. In addition, melatonin increased the protein levels of SIRT1, Beclin1, and LC3‐II, a hallmark protein of autophagy, and reduced the levels of acetylated‐Lys310 in the p65 subunit of NF‐ĸB in SH‐SY5Y cells treated wit...
Source: Journal of Pineal Research - April 12, 2017 Category: Research Authors: Chutikorn Nopparat, Puritat Sinjanakhom, Piyarat Govitrapong Tags: ORIGINAL ARTICLE Source Type: research
Melatonin alleviates inflammasome ‐induced pyroptosis through inhibiting NF‐κB/GSDMD signal in mice adipose tissue
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - April 11, 2017 Category: Research Authors: Zhenjiang Liu, Lu Gan, Yatao Xu, Dan Luo, Qian Ren, Song Wu, Chao Sun Tags: Original Article Source Type: research
Melatonin protects cardiac microvasculature against ischemia/reperfusion injury via suppression of mitochondrial fission ‐VDAC1‐HK2‐mPTP‐mitophagy axis
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - April 11, 2017 Category: Research Authors: Hao Zhou, Ying Zhang, Shunying Hu, Chen Shi, Pingjun Zhu, Qiang Ma, Qinhua Jin, Feng Cao, Feng Tian, Yundai Chen Tags: Original Article Source Type: research
Issue Information
(Source: Journal of Pineal Research)
Source: Journal of Pineal Research - April 6, 2017 Category: Research Tags: ISSUE INFORMATION Source Type: research
Chloroplast overexpression of rice caffeic acid O ‐methyltransferase increases melatonin production in chloroplasts via the 5‐methoxytryptamine pathway in transgenic rice plants
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - April 1, 2017 Category: Research Authors: Geun ‐Hee Choi, Hyoung Yool Lee, Kyoungwhan Back Tags: Original Article Source Type: research
Melatonin administration to wild ‐type mice and non‐treated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - March 31, 2017 Category: Research Authors: Ibtissem Rahim, Bahia Djerdjouri, Ramy K. Sayed, Marisol Fern ández‐Ortiz, Beatriz Fernández‐Gil, Agustín Hidalgo‐Gutiérrez, Luis C López, Germaine Escames, Russel J Reiter, Dario Acuna‐Castroviejo Tags: Original Article Source Type: research
Melatonin: antioxidant and modulatory properties in age ‐related changes during Trypanosoma cruzi infection
This article is protected by copyright. All rights reserved. (Source: Journal of Pineal Research)
Source: Journal of Pineal Research - March 30, 2017 Category: Research Authors: V ânia Brazão, Fabricia Helena Santello, Rafaela Pravato Colato, Tamires Tesch Mazotti, Lucas Favaretto Tazinafo, Míriam Paula Alonso Toldo, Gabriel Tavares do Vale, Carlos Renato Tirapelli, José Clóvis do Prado Tags: Original Article Source Type: research
