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Drinking status but not acute alcohol consumption influences delay discounting
ConclusionsOur data suggest that heavier drinkers discount the value of delayed rewards more steeply than lighter drinkers. Delay discounting may therefore be a promising marker of heavy alcohol consumption in social drinkers. (Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - July 1, 2017 Category: Psychiatry Authors: Sally Adams, Angela S. Attwood, Marcus R. Munaf ò Tags: RESEARCH ARTICLE Source Type: research

Resting ‐state fMRI and social cognition: An opportunity to connect
Abstract Many psychiatric disorders are characterized by altered social cognition. The importance of social cognition has previously been recognized by the National Institute of Mental Health Research Domain Criteria project, in which it features as a core domain. Social task‐based functional magnetic resonance imaging (fMRI) currently offers the most direct insight into how the brain processes social information; however, resting‐state fMRI may be just as important in understanding the biology and network nature of social processing. Resting‐state fMRI allows researchers to investigate the functional relationships b...
Source: Human Psychopharmacology: Clinical and Experimental - July 1, 2017 Category: Psychiatry Authors: Alex Doruyter, Nynke A. Groenewold, Patrick Dupont, Dan J. Stein, James M. Warwick Tags: SHORT COMMUNICATION Source Type: research

The impact of alcohol hangover symptoms on cognitive and physical functioning, and mood
In conclusion, whereas severity and impact scores usually correspond well, some frequently reported symptoms with moderate to high severity scores had little impact on mood, and cognitive and physical functioning (i.e., reduced appetite, regret, and thirst). (Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - July 1, 2017 Category: Psychiatry Authors: Marith Schrojenstein Lantman, Marlou Mackus, Aurora J.A.E. Loo, Joris C. Verster Tags: RESEARCH ARTICLE Source Type: research

Impairment due to combined sleep restriction and alcohol is not mitigated by decaying breath alcohol concentration or rest breaks
ConclusionsThese findings suggest that (a) falling BrACs are an inadequate guide for performance/safety and (b) rest breaks without sleep are not a safety measure for mitigating performance impairment when consuming alcohol following restricted sleep. (Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - July 1, 2017 Category: Psychiatry Authors: Jessica E. Manousakis, Clare Anderson Tags: RESEARCH ARTICLE Source Type: research

Diagnostic clusters associated with an early onset schizophrenia diagnosis among children and adolescents
(Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - June 28, 2017 Category: Psychiatry Tags: ERRATUM Source Type: research

Effectiveness of agomelatine on anhedonia in depressed patients: An outpatient, open ‐label, real‐world study
(Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - June 28, 2017 Category: Psychiatry Tags: CORRIGENDUM Source Type: research

Patterns of use and toxicity of new para ‐halogenated substituted cathinones: 4‐CMC (clephedrone), 4‐CEC (4‐chloroethcatinone) and 4‐BMC (brephedrone)
ConclusionSince the emergence of these substances could prove to be the next step to the cat‐and‐mouse game existing between drug producers and legislation, further clinical and epidemiological research should be carried out in order to build evidence to support policy for public health issues. (Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - June 28, 2017 Category: Psychiatry Authors: Marc Grifell, Mireia Ventura, Xo án Carbón, Pol Quintana, Liliana Galindo, Álvaro Palma, Ivan Fornis, Cristina Gil, Magi Farre, Marta Torrens Tags: SPECIAL ISSUE ON NOVEL PSYCHOACTIVE SUBSTANCES Source Type: research

Utility of Web search query data in testing theoretical assumptions about mephedrone
ConclusionsThe results might provide support for the hypothesis that mephedrone's popularity was highly correlated with its legal status as well as it functioned as a potential substitute for MDMA. Google Trends was found to be a useful tool for testing theoretical assumptions about NPS. (Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - June 28, 2017 Category: Psychiatry Authors: M áté Kapitány‐Fövény, Zsolt Demetrovics Tags: SPECIAL ISSUE ON NOVEL PSYCHOACTIVE SUBSTANCES Source Type: research

The use of supplements and performance and image enhancing drugs in fitness settings: A exploratory cross ‐sectional investigation in the United Kingdom
ConclusionThis pilot study identified the emergence of a new drug trend in fitness settings and showed a potential relationship to exercise addiction, anxiety disorders and low self‐esteem. The Internet played a crucial role in disseminating often untested products, including PIEDs without medical supervision and unwanted side‐effects were reported. More studies in the field are required in order to safeguard public health and inform policy making. (Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - June 28, 2017 Category: Psychiatry Authors: Roisin Mooney, Pierluigi Simonato, Risha Ruparelia, Andres Roman ‐Urrestarazu, Giovanni Martinotti, Ornella Corazza Tags: SPECIAL ISSUE ON NOVEL PSYCHOACTIVE SUBSTANCES Source Type: research

Intended and unintended use of cathinone mixtures
ConclusionRaising awareness of NPS, education, and training of health care professionals are paramount in reducing harms related to cathinone use. (Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - June 28, 2017 Category: Psychiatry Authors: Amira Guirguis, John Martin Corkery, Jacqueline Leslie Stair, Stewart Brian Kirton, Mire Zloh, Fabrizio Schifano Tags: SPECIAL ISSUE ON NOVEL PSYCHOACTIVE SUBSTANCES Source Type: research

4,4 ′‐Dimethylaminorex (“4,4′‐DMAR”; “Serotoni”) misuse: A Web‐based study
ConclusionsAlthough being characterized by a number of methodological limitations, the social networks' Web monitoring approach (netnography) may be helpful to better understand some of the clinical and psychopharmacological issues pertaining to a range of novel psychoactive substances, including 4,4′‐DMAR, for which only extremely little, if any, scientific knowledge is available. (Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - June 28, 2017 Category: Psychiatry Authors: Barbara Loi, Mire Zloh, Maria Antonietta De Luca, Nicholas Pintori, John Corkery, Fabrizio Schifano Tags: SPECIAL ISSUE ON NOVEL PSYCHOACTIVE SUBSTANCES Source Type: research

An insight into the deep web; why it matters for addiction psychiatry?
ConclusionsThis paper represents a complete or systematical guideline about the deep web, specifically focusing on practical information on online drug marketplaces, useful for addiction's professionals. (Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - June 28, 2017 Category: Psychiatry Authors: Laura Orsolini, Duccio Papanti, John Corkery, Fabrizio Schifano Tags: SPECIAL ISSUE ON NOVEL PSYCHOACTIVE SUBSTANCES Source Type: research

Repeated subcutaneous administrations of krokodil causes skin necrosis and internal organs toxicity in Wistar rats: putative human implications
ConclusionsThese findings contribute notably to comprehension of the local and systemic toxicological impact of this complex drug mixture on major organs and will hopefully be useful for the development of appropriate treatment strategies towards the human toxicological effects of krokodil. (Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - June 28, 2017 Category: Psychiatry Authors: Emanuele Amorim Alves, Pedro Brand ão, João Filipe Neves, Sara Manuela Cravo, José Xavier Soares, Jean‐Paul C. Grund, José Alberto Duarte, Carlos M.M. Afonso, Annibal Duarte Pereira Netto, Félix Carvalho, Ricardo Jorge Dinis‐Oliveira Tags: SPECIAL ISSUE ON NOVEL PSYCHOACTIVE SUBSTANCES Source Type: research

From concept(ion) to life after death/the grave: The ‘natural’ history and life cycle(s) of novel psychoactive substances (NPS)
Abstract A range of information needs should be met in order to better understand and predict the longevity/existence of novel psychoactive substances (NPS). This conceptual paper argues that one way of assessing how long a molecule may be around is to document how the life cycles or natural histories of ‘traditional’ drugs and NPS evolve. The earliest indication of the possible appearance of a new substance might be evidenced on the DeepWeb. However, this means they are less visible, in line with the clandestine nature of drug use and supply. Therefore, monitoring discussion groups/fora needs the development of new me...
Source: Human Psychopharmacology: Clinical and Experimental - June 28, 2017 Category: Psychiatry Authors: John Martin Corkery, Laura Orsolini, Duccio Papanti, Fabrizio Schifano Tags: SPECIAL ISSUE ON NOVEL PSYCHOACTIVE SUBSTANCES Source Type: research

1 ‐cyclohexyl‐x‐methoxybenzene derivatives, novel psychoactive substances seized on the internet market. Synthesis and in vivo pharmacological studies in mice
ConclusionsFor the first time, this study demonstrates that systemic administration of 1‐cyclohexyl‐x‐methoxybenzene compounds markedly inhibit visual response, promote analgesia, and induce core temperature alterations in mice. This data, although obtained in animal model, suggest their possible hazard for human health (i.e., hyperthermia and sensorimotor alterations). In particular, these novel psychoactive substances may have a negative impact in many daily activities, greatly increasing the risk factors for workplace accidents and traffic injuries. (Source: Human Psychopharmacology: Clinical and Experimental)
Source: Human Psychopharmacology: Clinical and Experimental - June 28, 2017 Category: Psychiatry Authors: Anna Fantinati, Andrea Ossato, Sara Bianco, Isabella Canazza, Fabio De Giorgio, Claudio Trapella, Matteo Marti Tags: SPECIAL ISSUE ON NOVEL PSYCHOACTIVE SUBSTANCES Source Type: research